Otwarty dostęp

Exenatide improves antioxidant capacity and reduces the expression of LDL receptors and PCSK9 in human insulin-secreting 1.1E7 cell line subjected to hyperglycemia and oxidative stress

Łukasz Bułdak

Łukasz Bułdak

Department of Internal Medicine and Clinical Pharmacology, School of Medicine in Katowice, Medical University of SilesiaKatowice, Poland
Profil Orcid
Wyszukaj tego autora
Sciendo|Google Scholar
Bułdak, Łukasz
, 
Estera Skudrzyk

Estera Skudrzyk

Department of Internal Medicine and Clinical Pharmacology, School of Medicine in Katowice, Medical University of SilesiaKatowice, Poland
Profil Orcid
Wyszukaj tego autora
Sciendo|Google Scholar
Skudrzyk, Estera
, 
Grzegorz Machnik

Grzegorz Machnik

Department of Internal Medicine and Clinical Pharmacology, School of Medicine in Katowice, Medical University of SilesiaKatowice, Poland
Profil Orcid
Wyszukaj tego autora
Sciendo|Google Scholar
Machnik, Grzegorz
, 
Aleksandra Bołdys

Aleksandra Bołdys

Department of Internal Medicine and Clinical Pharmacology, School of Medicine in Katowice, Medical University of SilesiaKatowice, Poland
Profil Orcid
Wyszukaj tego autora
Sciendo|Google Scholar
Bołdys, Aleksandra
, 
Rafał Jakub Bułdak

Rafał Jakub Bułdak

Institute of Medical Sciences, University of OpoleOpole, Poland
Profil Orcid
Wyszukaj tego autora
Sciendo|Google Scholar
Bułdak, Rafał Jakub
 oraz 
Bogusław Okopień

Bogusław Okopień

Department of Internal Medicine and Clinical Pharmacology, School of Medicine in Katowice, Medical University of SilesiaKatowice, Poland
Profil Orcid
Wyszukaj tego autora
Sciendo|Google Scholar
Okopień, Bogusław
  
20 lut 2022
Exenatide improves antioxidant capacity and reduces the expression of LDL receptors and PCSK9 in human insulin-secreting 1.1E7 cell line subjected to hyperglycemia and oxidative stress's Cover Image
O artykule
Poprzedni artykuł
Następny artykuł
Zacytuj
Pobierz okładkę
Kategoria artykułu: Original Article
Data publikacji: 20 lut 2022
Zakres stron: 16 - 23
Otrzymano: 01 sty 2021
Przyjęty: 16 lip 2021
DOI: https://doi.org/10.2478/ahem-2021-0037
Słowa kluczowe
© 2022 Łukasz Bułdak et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Fig. 1

The impact of exenatide on the level of expression of p22 (a), catalase (b), glutathione peroxidase (c) and superoxide dismutase 1 (d). Data are expressed as means ± SEM. Asterisks indicate the level of statistical significance: * - p<0.05, ** - p<0.01
The impact of exenatide on the level of expression of p22 (a), catalase (b), glutathione peroxidase (c) and superoxide dismutase 1 (d). Data are expressed as means ± SEM. Asterisks indicate the level of statistical significance: * - p<0.05, ** - p<0.01

Fig. 2

The impact of exenatide on the level of expression of inducible nitric oxide (a), and the concentration of nitrite in culture media (b). Data are expressed as means ± SEM. Asterisks indicate the level of statistical significance: * - p<0.05, ** - p<0.01
The impact of exenatide on the level of expression of inducible nitric oxide (a), and the concentration of nitrite in culture media (b). Data are expressed as means ± SEM. Asterisks indicate the level of statistical significance: * - p<0.05, ** - p<0.01

Fig. 3

The impact of exenatide on the concentration of insulin in culture media (a), the level of expression of LDL receptor (b) and PCSK9 (c). Data are expressed as means ± SEM. Asterisks indicate the level of statistical significance: * - p<0.05, ** - p<0.01
The impact of exenatide on the concentration of insulin in culture media (a), the level of expression of LDL receptor (b) and PCSK9 (c). Data are expressed as means ± SEM. Asterisks indicate the level of statistical significance: * - p<0.05, ** - p<0.01
Język:
Angielski
Częstotliwość wydawania:
1 razy w roku
Dziedziny czasopisma:
Nauki biologiczne, Biologia molekularna, Mikrobiologia i wirusologia, Medycyna, Podstawowe nauki medyczne, Immunologia
Kanał RSS czasopisma