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Application potential of modulation of cyclooxygenase-2 activity: a cognitive approach

Katarzyna Stachowicz

Katarzyna Stachowicz

Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of SciencesKraków, Poland
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Stachowicz, Katarzyna
  
13 dic 2021
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Categoria dell'articolo: Review
Pubblicato online: 13 dic 2021
Pagine: 837 - 846
Ricevuto: 18 dic 2020
Accettato: 07 giu 2021
DOI: https://doi.org/10.2478/ahem-2021-0022
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© 2021 Katarzyna Stachowicz, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Figure 1

Schematic diagram of omega-6 and omega-3 PUFA pathways, taking into account diet and diseases in case of imbalance between omega-6 and omega-3.
Schematic diagram of omega-6 and omega-3 PUFA pathways, taking into account diet and diseases in case of imbalance between omega-6 and omega-3.

Figure 2

Basic differences and similarities between COX isoenzymes (COX-1 and COX-2). Cellular and organ expression.
Basic differences and similarities between COX isoenzymes (COX-1 and COX-2). Cellular and organ expression.

Figure 3

Participation of COX in prostanoid biosynthesis and transformations. PGG2 (prostaglandin G2) and PGH2 (prostaglandin H2) as products of COX activity.
Participation of COX in prostanoid biosynthesis and transformations. PGG2 (prostaglandin G2) and PGH2 (prostaglandin H2) as products of COX activity.

Figure 4

Schematic diagram of pathways influencing COX/COX-2 expression in the pathomechanism of cognitive abnormalities/AD.
Schematic diagram of pathways influencing COX/COX-2 expression in the pathomechanism of cognitive abnormalities/AD.
Lingua:
Inglese
Frequenza di pubblicazione:
1 volte all'anno
Argomenti della rivista:
Scienze biologiche, Biologia molecolare, Microbiologia e virologia, Medicina, Scienze medicali di base, Immunologia
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