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Application potential of modulation of cyclooxygenase-2 activity: a cognitive approach

Katarzyna Stachowicz

Katarzyna Stachowicz

Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of SciencesKraków, Poland
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Stachowicz, Katarzyna
  
13 dic 2021
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Categoría del artículo: Review
Publicado en línea: 13 dic 2021
Páginas: 837 - 846
Recibido: 18 dic 2020
Aceptado: 07 jun 2021
DOI: https://doi.org/10.2478/ahem-2021-0022
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© 2021 Katarzyna Stachowicz, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Figure 1

Schematic diagram of omega-6 and omega-3 PUFA pathways, taking into account diet and diseases in case of imbalance between omega-6 and omega-3.
Schematic diagram of omega-6 and omega-3 PUFA pathways, taking into account diet and diseases in case of imbalance between omega-6 and omega-3.

Figure 2

Basic differences and similarities between COX isoenzymes (COX-1 and COX-2). Cellular and organ expression.
Basic differences and similarities between COX isoenzymes (COX-1 and COX-2). Cellular and organ expression.

Figure 3

Participation of COX in prostanoid biosynthesis and transformations. PGG2 (prostaglandin G2) and PGH2 (prostaglandin H2) as products of COX activity.
Participation of COX in prostanoid biosynthesis and transformations. PGG2 (prostaglandin G2) and PGH2 (prostaglandin H2) as products of COX activity.

Figure 4

Schematic diagram of pathways influencing COX/COX-2 expression in the pathomechanism of cognitive abnormalities/AD.
Schematic diagram of pathways influencing COX/COX-2 expression in the pathomechanism of cognitive abnormalities/AD.
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Temas de la revista:
Ciencias de la vida, Biología molecular, Microbiología y virología, Medicina, Ciencias médicas básicas, Inmunología
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