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Accuracy of transthoracic echocardiography in diagnosis of cardiac myxoma: single center experience

Polona Kacar

Polona Kacar

Department of Cardiology, University Medical Center LjubljanaLjubljana, Slovenia
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Kacar, Polona
, 
Nejc Pavsic

Nejc Pavsic

Department of Cardiology, University Medical Center LjubljanaLjubljana, Slovenia
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Pavsic, Nejc
, 
Mojca Bervar

Mojca Bervar

Department of Cardiology, University Medical Center LjubljanaLjubljana, Slovenia
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Bervar, Mojca
, 
Zvezdana Dolenc Strazar

Zvezdana Dolenc Strazar

Faculty of Medicine, University of LjubljanaLjubljana, Slovenia
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Strazar, Zvezdana Dolenc
 and 
Katja Prokselj

Katja Prokselj

  • Department of Cardiology, University Medical Center LjubljanaLjubljana, Slovenia
  • Faculty of Medicine, University of LjubljanaLjubljana, Slovenia
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Prokselj, Katja
  
Jan 22, 2025
Accuracy of transthoracic echocardiography in diagnosis of cardiac myxoma: single center experience's Cover Image
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Article Category: research article
Published Online: Jan 22, 2025
Page range: 63 - 68
Received: Feb 10, 2024
Accepted: Dec 08, 2024
DOI: https://doi.org/10.2478/raon-2025-0007
Keywords
© 2025 Polona Kacar et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.

FIGURE 1.

(A) Transthoracic echocardiography, apical 4-chamber view. Cardiac mass in left atrium is attached to the interatrial septum in the region of the fossa ovalis (arrow). Histopathological characterization confirmed cardiac myxoma. (B) Abundant myxoid stroma with clusters of myxoma cells forming cords and ring structures (HE 100×). LA = left atrium; LV = left ventricle; RA = right atrium; RV = right ventricle
(A) Transthoracic echocardiography, apical 4-chamber view. Cardiac mass in left atrium is attached to the interatrial septum in the region of the fossa ovalis (arrow). Histopathological characterization confirmed cardiac myxoma. (B) Abundant myxoid stroma with clusters of myxoma cells forming cords and ring structures (HE 100×). LA = left atrium; LV = left ventricle; RA = right atrium; RV = right ventricle

FIGURE 2.

Flow diagram showing the diagnostic accuracy of preoperative TTE in patients with suspected CM. The predictive value and accuracy of preoperative TTE was calculated using the results of pathohistological examination as the gold FN = false negative; FP = false positive; TP = true positive; TN = true negative; TTE = transthoracic echocardiography
Flow diagram showing the diagnostic accuracy of preoperative TTE in patients with suspected CM. The predictive value and accuracy of preoperative TTE was calculated using the results of pathohistological examination as the gold FN = false negative; FP = false positive; TP = true positive; TN = true negative; TTE = transthoracic echocardiography

Comparison of demographic and echocardiographic characteristics between pathohistologically confirmed cardiac myxoma (CM) and non-myxoma (NM) groups

Characteristic CM (n= 39) NM (n = 14) p value
Age (years) 63.1 ± 13.6 66.6 ± 15.1 0.434
Sex (female) 25 (64) 10 (71) 0.620
Location
    Typical 28 (72) 0 P < 0.001
    Atypical 11 (28) 14 (100) P < 0.001
Size (mm) 37.9 ± 18.3 24.3 ± 13.2 0.017

Preoperative echocardiographic characteristics of the cardiac myxoma (CM) and non-myxoma (NM) group

Echocardiographic characteristics CM (n=45) NM (n =8)
Mean size (mm) 35.3 ± 18.6 (range: 10–81) 30.3 ± 16.9 (range: 8–50)
Location
  Left atrium 36 (80) 2 (25)
    Fossa ovalis 27 (75)
    Mitral valve 4 (11) 1 (50)
    Posterior interatrial septum 3 (8)
    Free left atrial wall 1 (3) 1 (50)
    Left atrial appendage 1 (3)
  Right atrium 8 (18) 4 (50)
  Left ventricle 1 (2) 1 (12)
  Aortic valve 1 (12)
Mobility
  Mobile 32 (71) 7 (88)
  Non-mobile 5 (11)
  No data available 8 (18) 1 (12)
Surface
  Smooth or lobulated 28 (62) 1 (12)
  Villous 8 (18) 3 (38)
  No data available 9 (20) 4 (50)
Obstruction (present) 11 (24) 2 (25)
  Mitral valve 10 (21) 1 (50)
  Tricuspid valve 1 (9) 1 (50)
Language:
English
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4 times per year
Journal Subjects:
Medicine, Clinical Medicine, Internal Medicine, Haematology, Oncology, Radiology
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