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Accuracy of transthoracic echocardiography in diagnosis of cardiac myxoma: single center experience

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,

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Zvezdana Dolenc Strazar

Strazar, Zvezdana Dolenc

und

Prokselj, Katja

22. Jan. 2025

Accuracy of transthoracic echocardiography in diagnosis of cardiac myxoma: single center experience's Cover Image

Radiology and Oncology

Band 59 (2025): Heft 1 (März 2025)

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Artikel-Kategorie: research article

Online veröffentlicht: 22. Jan. 2025

Seitenbereich: 63 - 68

Eingereicht: 10. Feb. 2024

Akzeptiert: 08. Dez. 2024

DOI: https://doi.org/10.2478/raon-2025-0007

Schlüsselwörter
cardiac mass, cardiac myxoma, cardiovascular imaging, echocardiography

© 2025 Polona Kacar et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

(A) Transthoracic echocardiography, apical 4-chamber view. Cardiac mass in left atrium is attached to the interatrial septum in the region of the fossa ovalis (arrow). Histopathological characterization confirmed cardiac myxoma. (B) Abundant myxoid stroma with clusters of myxoma cells forming cords and ring structures (HE 100×).
LA = left atrium; LV = left ventricle; RA = right atrium; RV = right ventricle — (A) Transthoracic echocardiography, apical 4-chamber view. Cardiac mass in left atrium is attached to the interatrial septum in the region of the fossa ovalis (arrow). Histopathological characterization confirmed cardiac myxoma. (B) Abundant myxoid stroma with clusters of myxoma cells forming cords and ring structures (HE 100×). LA = left atrium; LV = left ventricle; RA = right atrium; RV = right ventricle

Flow diagram showing the diagnostic accuracy of preoperative TTE in patients with suspected CM. The predictive value and accuracy of preoperative TTE was calculated using the results of pathohistological examination as the gold
FN = false negative; FP = false positive; TP = true positive; TN = true negative; TTE = transthoracic echocardiography — Flow diagram showing the diagnostic accuracy of preoperative TTE in patients with suspected CM. The predictive value and accuracy of preoperative TTE was calculated using the results of pathohistological examination as the gold FN = false negative; FP = false positive; TP = true positive; TN = true negative; TTE = transthoracic echocardiography

Comparison of demographic and echocardiographic characteristics between pathohistologically confirmed cardiac myxoma (CM) and non-myxoma (NM) groups

Characteristic	CM (n= 39)	NM (n = 14)	p value
Age (years)	63.1 ± 13.6	66.6 ± 15.1	0.434
Sex (female)	25 (64)	10 (71)	0.620
Location
Typical	28 (72)	0	P < 0.001
Atypical	11 (28)	14 (100)	P < 0.001
Size (mm)	37.9 ± 18.3	24.3 ± 13.2	0.017

Preoperative echocardiographic characteristics of the cardiac myxoma (CM) and non-myxoma (NM) group

Echocardiographic characteristics	CM (n=45)	NM (n =8)
Mean size (mm)	35.3 ± 18.6 (range: 10–81)	30.3 ± 16.9 (range: 8–50)
Location
Left atrium	36 (80)	2 (25)
Fossa ovalis	27 (75)
Mitral valve	4 (11)	1 (50)
Posterior interatrial septum	3 (8)
Free left atrial wall	1 (3)	1 (50)
Left atrial appendage	1 (3)
Right atrium	8 (18)	4 (50)
Left ventricle	1 (2)	1 (12)
Aortic valve		1 (12)
Mobility
Mobile	32 (71)	7 (88)
Non-mobile	5 (11)
No data available	8 (18)	1 (12)
Surface
Smooth or lobulated	28 (62)	1 (12)
Villous	8 (18)	3 (38)
No data available	9 (20)	4 (50)
Obstruction (present)	11 (24)	2 (25)
Mitral valve	10 (21)	1 (50)
Tricuspid valve	1 (9)	1 (50)

Sprache:: Englisch

Zeitrahmen der Veröffentlichung:: 4 Hefte pro Jahr
Fachgebiete der Zeitschrift:: Medizin, Klinische Medizin, Allgemeinmedizin, Innere Medizin, Hämatologie, Onkologie, Radiologie

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