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Fig. 1
Components of the cDNA biosensor system.
Fig. 2
Diagram of functionalized gold surface quartz crystal and representation of the cDNA anchorage and hybridization.
Fig. 3
Nyquiste plot EBiS spectra for the three genes studied (NLRP3, IL-1B and Caspase 1) as well as control (vehicle) and negative control (non-specific gene) conditions.
Fig. 4
Relative integrated EBiS vs relative qPCR expression of the genes NLRP3, IL-1β, and Casp-1. One-way ANOVA test *p<0.01, **p<0.05.
Fig. 5
Numerical modelling of a simple DNA molecule anchoring on an electrode surface. Frequency response of the RC equivalent circuit calculated by LTspice IV.