1. bookTom 66 (2022): Zeszyt 4 (December 2022)
Informacje o czasopiśmie
Pierwsze wydanie
30 Mar 2016
Częstotliwość wydawania
4 razy w roku
Otwarty dostęp

Toxic Effects of Cadmium on the Female Reproductive Organs a Review

Data publikacji: 30 Dec 2022
Tom & Zeszyt: Tom 66 (2022) - Zeszyt 4 (December 2022)
Zakres stron: 56 - 66
Otrzymano: 06 Oct 2022
Przyjęty: 14 Nov 2022
Informacje o czasopiśmie
Pierwsze wydanie
30 Mar 2016
Częstotliwość wydawania
4 razy w roku

1. Akar, Y., Ahmad, N., Khalıd, M., 2018: The effect of cadmium on the bovine in vitro oocyte maturation and early embryo development. Int. J. Vet. Sci. Med., 6, 73. DOI: 10. 1016/j.ijvsm.2018. Search in Google Scholar

2. Ali, I., Penttinen-Damdimopoulou, P. E., Mäkelä, S. I., Berglund, M., Stenius, U., Akesson, A., et al., 2010: Estrogen-like effects of cadmium in vivo do notappear to be mediated via the classical estrogen receptor transcriptional pathway. Environ. Health Perspect., 118, 1389–1394. DOI: 10.1289/ehp.1001967.10.1289/ehp.1001967295791720525538 Search in Google Scholar

3. Angenard, G., Muczynski, V., Coffigny, H., Pairault, C., Duquenne, C., Frydman, R., et al., 2010: Cadmium increases human foetal germ cell apoptosis. Environ. Health Perspect., 118, 331–337. DOI: 10.1289/ehp.0900975.10.1289/ehp.0900975285475920064782 Search in Google Scholar

4. Aoyagi, T., Ishikawa, H., Miyaji, K., Hayakawa, K., Hata, M., 2002: Cadmium-induced testicular damage in a rat model of subchronic intoxication. Reprod. Med. Biol., 1, 59–63. DOI: 10.1046/j.1445-5781.2002.00010.x.10.1046/j.1445-5781.2002.00010.x589178429662348 Search in Google Scholar

5. Belani, M., Shah, P., Banker, M., Gupta, S., 2016: Dual effect of insulin resistance and cadmium on human granulosa cells ‒ In vitro study. Toxicol. Appl. Pharmacol., 15, 119–130. DOI: 10.1016/j.taap.2016. Search in Google Scholar

6. Bernhoft, R. A., 2013: Cadmium toxicity and treatment. Sci. World J., 3, 2013 : 394652. DOI: 10.1155/2013/394652.10.1155/2013/394652368608523844395 Search in Google Scholar

7. Bertin, G., Averbeck, D., 2006: Cadmium: Cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences. Biochimie, 88, 1549–1559. DOI: 10.1016/j.biochi.2006. Search in Google Scholar

8. Beyersmann, D., Hechtenberg, S., 1997: Cadmium, gene regulation, and cellular signalling in mammalian cells. Toxicol. Appl. Pharmacol.,144, 247–261. DOI: 10.1006/taap. 1997.8125. Search in Google Scholar

9. Byrne, C., Divekar, S. D., Storchan, G. B., 2009: Parodi-gene regulation, and cellular signalling in mammalian cells. Toxicol. Appl. Pharmacol., 144, 247–261.10.1006/taap.1997.81259194408 Search in Google Scholar

10. Chedrese, P. J., Rodway, M. R., Swan, C. L., Gillio-Meina, C., 1998: Establishment of a stable steroidogenic porcine granulosa cell line. J. Molec. Endocrinol., 20, 287–292. DOI: 10.1677/jme.0.0200287.10.1677/jme.0.02002879584843 Search in Google Scholar

11. Cheng, Y., Zhang, J., Wu, T., Jiang, X., Jia, H., Qing, S., et al., 2019: Reproductive toxicity of acute Cd exposure in mouse: Resulting in oocyte defects and decreased female fertility. Toxicol. Appl. Pharmacol., 379, 114684. DOI: 10.1016/j.taap.2019.114684.10.1016/j.taap.2019.11468431325558 Search in Google Scholar

12. Copius, Peereboom-Stegeman, J. H., Jongstra-Spaapen, E., Leene, W., Oosting, H., Venema, H., de Moor, E., Gerrisen, W. J., 1987: The effects of long-term exposure to cadmium on the small blood vessels in the rat uterus: A light microscopic study. Ecotoxicol. Environ. Saf., 14, 288–297. DOI: 10.1016/0147-6513(87)90072-8.10.1016/0147-6513(87)90072-83691381 Search in Google Scholar

13. Copius, Peereboom-Stegeman, J. H., 1989: Cadmium effects on the female reproductive tract. Toxicol. Environ. Chem., 23, 91–99. DOI: 10.1080/02772248909357454.10.1080/02772248909357454 Search in Google Scholar

14. Cuypers, M., Plusquin, T., Remans,T., et al., 2010: Cadmium stress: An oxidative challenge. Biometals, 23, 927–940. DOI: 10.1007/s10534-010-9329-x.10.1007/s10534-010-9329-x20361350 Search in Google Scholar

15. Deckert, J., 2005: Cadmium toxicity in plants: Is there any analogy to its carcinogenic effect in mammalian cells. Biometals, 18, 475–481. DOI: 10.1007/s10534-005-1245-0.10.1007/s10534-005-1245-016333748 Search in Google Scholar

16. Diao, S. Y., Zhang, L. Z., Yuan, H., 2005: Progress in the toxicity mechanism of cadmium. Prog. Vet. Med., 26, 49–51. Search in Google Scholar

17. Dong, F., Li, J., Lei, W. L., Wang, F., Wang, Y., Ouyang, Y. Ch., et al., 2020: Chronic cadmium exposure causes oocyte meiotic arrest by disrupting spindle assembly checkpoint and maturation promoting factor. Reprod. Toxicol., 96, 141–149. DOI: 10.1016/j.reprotox.2020. Search in Google Scholar

18. Habbeebu, S. S., Liu, J., Klaassen, C. D., 1998: Cadmium-induced apoptosis in mouse liver. Toxicol. Appl. Pharmacol., 149, 203–209. DOI: 10.1006/taap.1997.8334.10.1006/taap.1997.83349571989 Search in Google Scholar

19. Hartwig, A., 2013: Cadmium and cancer. Met. Ions Life Sci., 11, 491–507. DOI: 10.1007/978-94-007-5179-815. Search in Google Scholar

20. Henson, M. C., Chedrese, P. J., 2004: Endocrine disruption by cadmium a common environmental toxicant with paradoxical effects on reproduction. Exp. Biol. Med., 229, 383–392. DOI: 10.1177/153537020422900506.10.1177/15353702042290050615096650 Search in Google Scholar

21. Henson, M. C., Anderson, M. B., 2000: The effects of cadmium on placental endocrine function. Recent Res. Dev. Endo crinol., 1, 37–47. Search in Google Scholar

22. Höfer, N., Diel, P., Wittsiepe, J., Wilhelm, M., Degen, G. H., 2009: Dose- and route-dependent hormonal activity of the metalloestrogen cadmium in the rat uterus. Toxicol. Lett., 191, 123–131.10.1016/j.toxlet.2009.08.01419703529 Search in Google Scholar

23. Huff, J., Lunn, R. M., Waalkes, M. P., Tomatis, L., Infante, P. F., 2007: Cadmium-induced cancers in animals and in humans. Intern. J. Occup. Environ. Health., 13, 202–212. DOI: 10.1179/oeh.2007. Search in Google Scholar

24. Järup, L., Berglund, M., Elinder, C. G., Nordberg, G., Vahter, M., 1998: Health effects of cadmium exposure. A review of the literature and a risk estimate. Scand. J. Work. Environ. Health, 24, 1–51. Search in Google Scholar

25. Järup, L., Hellström, L., Alfvén, T., Carlsson, M. D., Grubb, A., Persson, B., et al., 2000: Low level exposure to cadmium and early kidney damage: The OSCAR study. Occup. Environ. Med., 57, 668–672.10.1136/oem.57.10.668173987410984338 Search in Google Scholar

26. Jin, T., Kong, Q., Ye, T., Wu, X., Nordberg, G. F., 2004: Renal dysfunction of cadmium-exposed workers residing in a cadmium-polluted environment. Biometals, 17, 513–518.10.1023/B:BIOM.0000045730.01633.4515688855 Search in Google Scholar

27. Jin, L., Luo, L., Wang, D., Wang, W., Zhu, J., Chen, N., et al., 2019: Cadmium induces ovarian granulosa cell damage by activating PERK-eIF2α-ATF4 through endoplasmic reticulum stress. Biol. Reprod., 100, 292–299. DOI: 10.1093/biol re/ioy169. Search in Google Scholar

28. Johnson, M. D., Kenney, N., Stoica, A., Hilakivi-Clarke, L., Singh, B., Chepko, G., et al., 2003: Cadmium mimics the in vivo effects of oestrogen in the uterus and mammary gland. Nat. Med., 9, 1081–1084. DOI: 10.1038/nm902.10.1038/nm90212858169 Search in Google Scholar

29. Kar, I., Patra, A. K., 2021: Tissue bioaccumulation and toxicopathological effects of cadmium and its dietary amelioration in poultry. Biol. Trace Elem. Res., 199, 3846–3868. DOI: 10.1007/s12011-020-02503-2.10.1007/s12011-020-02503-233405085 Search in Google Scholar

30. Kasuya, M., 2000: Recent epidemiological studies on itaiitai disease as a chronic cadmium poisoning in Japan. Water Sci. Technol., 42, 147–154. DOI: 10.2166/wst.2000.0563.10.2166/wst.2000.0563 Search in Google Scholar

31. Kim, J. L., Lim, W., Ko, Y., Kwon, H., Kim, S., Kim, O., et al., 2012: The effects of cadmium on VEGF-mediated angiogenesis in HUVECs. J. Appl. Toxicol., 32, 342–349.10.1002/jat.167721425301 Search in Google Scholar

32. Klaassen, C. D., Liu, J., Choudhuri, S., 1999: Metallothionein: an intracellular protein to protect against cadmium toxicity. Annu. Rev. Pharmacol. Toxicol., 39, 267–294. DOI: 10. 1146/annurev.pharmtox. Search in Google Scholar

33. Lafuente, A., Cano, P., Esquifino, A. I., 2003: Are cadmium effects on plasma gonadotropins, prolactin, ACTH, GH and TSH levels, dose-dependent ? Biometals, 16, 243–250. DOI: 10.1023/a:1020658128413.10.1023/A:102065812841312572682 Search in Google Scholar

34. Leoni, G., Bogliolo, L., Deiana, G., Berlinguer, F., Rosati, I., Pintus, P. P., et al., 2002: Influence of cadmium exposure on in vitro ovine gamete dysfunction. Reprod. Toxicol., 16, 371–377.10.1016/S0890-6238(02)00040-0 Search in Google Scholar

35. Li, H. Y., Wu, S. Y., 2002: Review of the female reproductive toxicity by cadmium. China Public Health, 18, 379–381. Search in Google Scholar

36. Li, Q., 2009: The effect of cadmium on oocyte apoptosis and DNA damage of female mice. In 6th OAPS Working Paper Series, Paper No. 2009-035. Search in Google Scholar

37. Li, Z., Li, T., Leng, Y., Chen, S., Liu, Q., Feng, J., et al., 2018: Hormonal changes and folliculogenesis in female off-spring of rats exposed to cadmium during gestation and lactation. Environ. Pollut., 238, 336–347. DOI: 10.1016/j.envpol. 2018.03.023. Search in Google Scholar

38. Liu, J., Wei, Qu., Kadiiska, M. B., 2009: Role of oxidative stress in cadmium toxicity and carcinogenesis. Toxicol. Appl. Pharmacol., 238, 209–214. DOI: 10.1016/j.taap.2009. Search in Google Scholar

39. Liu, J., Zhang, W., Li, H., 2010: Cadmium-induced increase in uterine wet weight and its mechanism. Birth Defects Res., 89, 43–49.10.1002/bdrb.2023320151473 Search in Google Scholar

40. Liu, J., Luo, L., Wang, D., Wang, W., Zhu, J., Li, Y., et al., 2019: Cadmium induces ovarian granulosa cell damage by activating PERK-eIF2α-ATF4 through endoplasmic reticulum stress. Biol. Reprod., 100, 1, 292–299. DOI: 10.1093/biolre/ioy169.10.1093/biolre/ioy16930137227 Search in Google Scholar

41. Liu, Y., Wen, X., Wang, D., Liao, X., 2021: Maternal exposure to trace cadmium affects gonadal differentiation and development in male offspring rats though a star pathway. Food Sci. Technol. Campinas, 41, 3, 635–642.10.1590/fst.24420 Search in Google Scholar

42. Lubo-Palma, A., Nava-Leal, C., Villasmil, V., Quevedo, A. L., Montiel, M., Simoes, D., Faría, C., 2006: Effects of cadmium on the ovarian parenchyma in Swiss albino mice. Invest. Clin., 47, 219–231. Search in Google Scholar

43. Luciano, A. M., Franciosi, F., Lodde, V., Corbani, D., Lazzari, G., Crotti, G., 2010: Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte maturation (IVM) test within ReProTect. Reprod. Toxicol., 30, 81–88. DOI: 10.1016/j.reprotox.2010.01.015. 44.10.1016/j.reprotox.2010.01.01520156549 Search in Google Scholar

44. Luevano, J., Damodaran, C., 2014: A review of molecular events of cadmium-induced carcinogenesis. J. Environ. Pathol. Toxicol. Oncol., 33, 183–194. DOI: 10.1615/jenviron patholtoxicoloncol.2014011075. Search in Google Scholar

45. Marettová, E., Maretta, M., Legáth, J., 2015: Toxic effects of cadmium on testis of birds and mammals: A review. Anim. Reprod. Sci.,155, 1–10. DOI: 10.1016/j.anireprosci.2015. 01.007. Search in Google Scholar

46. Markstrom, E., Svensson, E. Ch., Shao, R., et al., 2002: Survival factors regulating ovarian apoptosis ‒ dependence on follicle differentiation. Reproduction, 123, 23–30. DOI: 10.1530/rep.0.1230023. 47.10.1530/rep.0.123002311869183 Search in Google Scholar

47. Massányi, P., Uhrín, V., 1997: Histological changes in the uterus of rabbits after an administration of cadmium. J. Environ. Sci. Health Part A. Environ. Sci. Engin. Toxicol., 32, 1459–1466. DOI: 10.1080/10934529709376621.10.1080/10934529709376621 Search in Google Scholar

48. Nasiadek, M., Danilewicz, M., Sitarek, K., Świątkowska, E., Daragó, A., Stragierowicz, J., Kilanowicz, A., 2018: The effect of repeated cadmium oral exposure on the level of sex hormones, oestrous cyclicity, and endometrium morphometry in female rats. Environ. Sci. Pollut. Res. Int., 25, 28025–28038.10.1007/s11356-018-2821-5615367030066076 Search in Google Scholar

49. Nampoothiri, L. P., Gupta, S., 2006: Simultaneous effect of lead and cadmium on granulosa cells: A cellular model for ovarian toxicity. Reprod. Toxicol., 21, 179–185. DOI: 10. 1016/j.reprotox.2005. Search in Google Scholar

50. Nampoothiri, L., P., Agarwal, A., Gupta, S., 2007: Effect of coexposure to lead and cadmium on antioxidant status in rat ovarian granulose cells. Arch. Toxicol., 81, 145–150. DOI: 10.1007/s00204-006-0133-x.10.1007/s00204-006-0133-x16897041 Search in Google Scholar

51. Nandi, S., Gupta, P. S. P., Selvaraju, S., Roy, S. C., Ravindra, J. P., 2010: Effects of exposure to heavy metals on viability, maturation, fertilization, and embryonic development of buffalo (Bubalus bubalis) oocytes in vitro. Arch. Environ. Contam. Toxicol., 58, 194–204.10.1007/s00244-009-9342-719475365 Search in Google Scholar

52. Nna, V. U., Usman, U. Z., Ofutet, E. O., Owu, D. U., 2017: Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride-induced oxidative stress in the uterus and ovaries of female Wistar rats. Food Chem. Toxicol., 102, 143–155. DOI: 10.1016/j.fct.2017. Search in Google Scholar

53. Paksy, K., Varga, B., Naray, M., Kiss, I., Folly, G., Ung-vary, G., 1990: Uptake and distribution of Cd in the ovaries, adrenals and pituitary in pseudopregnant rats. Effects of Cd on progesterone levels. Environ. Res., 51, 83–89. DOI: 10. 1016/s0013-9351(05)80184-7.10.1016/S0013-9351(05)80184-7 Search in Google Scholar

54. Paksy, K., Varga, B., Lázár, P., 1992: Cadmium interferes with steroid biosynthesis in rat granulosa and luteal cells in vitro. Biometals, 5, 245–250.10.1007/BF01061225 Search in Google Scholar

55. Paksy, K., Rajczy, K., Forgacs, Z., Lazár, P., Bernard, A., Gati, I., et al., 1997: Effect of cadmium on morphology and steroidogenesis of cultured human ovarian granulosa cells. J. Appl. Toxicol., 17, 321–327. DOI: 10.1002/(sici)1099-1263 (199709)17:5<321:aid-jat443>3.0.co;2-e. Search in Google Scholar

56. Patra, R. C., Rautray, A. K., Swarup, D., 2011: Oxidative stress in lead and cadmium toxicity and its amelioration. Vet. Med. Int., 2011, 457327. DOI: 10.4061/2011/457327.10.4061/2011/457327 Search in Google Scholar

57. Piasek, M., Blanusa, M., Kostial, K., Laskey, J. W., 2001: Placental cadmium and progesterone concentrations in cigarette smokers. Reprod. Toxicol., 15, 673–681. DOI: 10.1016/s0890-6238(01)00174-5.10.1016/S0890-6238(01)00174-5 Search in Google Scholar

58. Piasek, M., Laskey, J. W., 1994: Acute cadmium exposure and ovarian steroidogenesis in cycling and pregnant rats. Re-prod. Toxicol., 8, 495–507.10.1016/0890-6238(94)90032-9 Search in Google Scholar

59. Piasek, M., Laskey, J. W., 1999: Effects of in vitro exposure on ovarian steroidogenesis in rats. J. Appl. Toxicol., 19, 211–217.10.1002/(SICI)1099-1263(199905/06)19:3<211::AID-JAT568>3.0.CO;2-4 Search in Google Scholar

60. Pillai, P., Pandya, C., Gupta, S., Gupta, S., 2010: Biochemical and molecular effects of gestational and lactational coexposure to lead and cadmium on ovarian steroidogenesis are associated with oxidative stress in F1 generation rats. J. Biochem. Mol. Toxicol., 24, 384–394. DOI: 10.1002/jbt. 20351. Search in Google Scholar

61. Prozialeck, W. C., Edwards, J. R., Nebert, D. W., Woods, J. M., Barchowsky, A., Atchison, W. D., 2008: The vascular system as a target of metal toxicity. Toxicol. Sci., 102, 207–218. DOI: 10.1093/toxsci/kfm263.10.1093/toxsci/kfm263 Search in Google Scholar

62. Qu, J., Wang, Q. X., Li, Y., 2022: The environment and female reproduction: Potential mechanism of cadmium poisoning to the growth and development of ovarian follicle. Ecotoxicol. Environ. Saf., 244, 114029. DOI: 10.1016/j.ecoenv. 2022.114029. Search in Google Scholar

63. Rani, A., Kumar, A., Lal, A., Pant, M., 2014:Cellular mechanisms of cadmium-induced toxicity: A review. Intern. J. Environ. Health Res., 24, 378–399. DOI: 10.1080/09603123. 2013.835032. Search in Google Scholar

64. Rehm, S., Waalkes, M. P., 1988: Cadmium-induced ovarian toxicity in hamsters, mice and rats. Fundam. Appl. Toxicol., 10, 635–647.10.1093/toxsci/10.4.635 Search in Google Scholar

65. Ronchetti, S. A., Miler, E. A., Duvilanski, B. H., Cabilla, J. P., 2013: Cadmium mimics oestrogen-driven cell proliferation and prolactin secretion from anterior pituitary cells. PLOS ONE, 8, e81101.10.1371/journal.pone.0081101 Search in Google Scholar

66. Rzymski, P., Tomczyk, K., Rzymski, P., Poniedzialek, B., Opala, T., Wilczak, M., 2015: Impact of heavy metals on the female reproductive system. Ann. Agric. Environ. Med., 22, 259–264. DOI: 10.5604/12321966.115207. Search in Google Scholar

67. Saksena, S. K., Salmonsen, R., 1983: Effects of cadmium chloride on ovulation and on induction of sterility in the female golden hamster. Biol. Reprod., 29, 249–256.10.1095/biolreprod29.1.249 Search in Google Scholar

68. Samuel, J. B. L., Stanley, J. A., Princess, R. A., Shanthi, P., Sebastian, M. S., 2011: Gestational cadmium exposure-induced ovotoxicity delays puberty through oxidative stress and impaired steroid hormone levels. J. Med. Toxicol., 7, 195–204. DOI: 10.1007/s13181-011-0143-9.10.1007/s13181-011-0143-9355021121373971 Search in Google Scholar

69. Shen, L. J., Zhou, I. F., Jin, T. I., 2001: Experimental study on the oestrogen-like effect of cadmium. J. Labour Med., 18, 67–69. Search in Google Scholar

70. Siu, E. R., Mruk, D. D., Porto, C. S., Cheng, C. Y., 2009: Cadmium-induced testicular injury. Toxicol. Appl. Pharmacol., 238, 240–249. DOI: 10.1016/j.taap.2009. Search in Google Scholar

71. Smida, A. D., Valderrama, X. P., Agostini, M. C., Furlan, M. A., Chedrese, J., 2004: Cadmium stimulates transcription of the cytochrome p450 side chain cleavage gene in genetically modified stable porcine granulosa cells. Biol. Reprod., 70, 25–31. DOI: 10.1016/j.taap.2009. Search in Google Scholar

72. Stohs, S. J., Bagchi, D., Hassoun, E., Bagchi, M., 2000: Oxidative mechanisms in the toxicity of chromium and cadmium ions. J. Environ. Pathol. Toxicol. Oncol., 19, 201–213. Search in Google Scholar

73. Stohs, S. J., Bagchi, D., Hassoun, E., Bagchi, M., 2001: Oxidative mechanisms in the toxicity of chromium and cadmium ions. J. Environ. Pathol. Toxicol. Oncol., 20, 77–88.10.1615/JEnvironPatholToxicolOncol.v20.i2.10 Search in Google Scholar

74. Stoica, A., Katzenellenbogen, B. S., Martin, M. B., 2000: Activation of estrogen receptor-α by the heavy metal cadmium. Mol. Endocrinol., 14, 545–552. DOI: 10.1210/mend.14.4.0441.10.1210/mend.14.4.044110770491 Search in Google Scholar

75. Takiguchi, M., Yoshihara, S., 2006: New aspects of cadmium as endocrine disruptor. J. Environ. Sci., 13, 107–116. Search in Google Scholar

76. Templeton, D. M., Liu, Y., 2010: Multiple roles of cadmium in cell death and survival. Chemico-Biological Interact., 188, 267–275. DOI: 10.1016/j.cbi.2010. Search in Google Scholar

77. Thévenod, F., 2009: Cadmium and cellular signalling cascades: To be or not to be ? Toxicol. Appl. Pharmacol., 2, 238–239. DOI: 10.1016/j.taap.2009. Search in Google Scholar

78. Thévenod, F., 2010: Catch me if you can ! Novel aspects of cadmium transport in mammalian cells. Biometals, 23, 857–875. DOI: 10.1007/s10534-010-9309-1.10.1007/s10534-010-9309-120204475 Search in Google Scholar

79. Thévenod, F., Lee, W. K., 2013: Cadmium and cellular signalling cascades: Interactions between cell death and survival pathways. Arch. Toxicol., 87, 1743–1786.10.1007/s00204-013-1110-923982889 Search in Google Scholar

80. Thompson J., Bannigan, J., 2008: Cadmium: toxic effects on the reproductive system and the embryo. Reprod. Toxicol., 25, 304–315. DOI: 10.1016/j.reprotox.2008. Search in Google Scholar

81. Van Kerkhove, E., Pennemans, V., Swennen, Q., 2010: Cadmium and transport of ions and substances across cell membranes and epithelia. Biom etals, 23, 823–855. DOI: 10. 1007/s10534-010-9357-6.10.1007/s10534-010-9357-620582616 Search in Google Scholar

82. Varga, B., Paksy, K., Náray, M., 1991: Distribution of cadmium in ovaries, adrenals and pituitary gland after chronic administration in rats. Acta Physiol. Hung.,78, 221–226. Search in Google Scholar

83. Vaskivuo, T. E., Anttonen, M., Herva, R., et al., 2001: Survival of human ovarian follicles from foetal to adult life: Apoptosis, apoptosis-related proteins, and transcription factor GATA-4. J. Clin. Endocrinol. Metab., 86, 3421–3429. DOI: 10.1210/jcem.86.7.7679.10.1210/jcem.86.7.767911443219 Search in Google Scholar

84. Vrsanska, S., Nagyova, E., Mlynarcikova, A., Fickova, M., Kolena, J., 2003: Components of cigarette smoke inhibit expansion of oocyte-cumulus complexes from porcine follicles. Physiol. Res., 52, 383–387. Search in Google Scholar

85. Waalkes, M. P., Anver, M. R., Diwan, B., 1999: Chronic toxic and carcinogenic effects of oral cadmium in the Noble (NBL/Cr) rat: Induction of neoplastic and proliferative lesions of the adrenal, kidney, prostate, and testes. J. Toxicol. Environ. Health., 58, 199–214. DOI: 10.1080/009841099157296.10.1080/00984109915729610591488 Search in Google Scholar

86. Waalkes, M. P., 2003: Cadmium carcinogenesis. Mutat. Res., 533, 107–120. DOI: 10.1016/j.mrfmmm.2003. Search in Google Scholar

87. Waisberg, M., Joseph, P., Hale, B., Beyersmann, D., 2003: Molecular and cellular mechanisms of cadmium carcinogen-esis. Toxicology, 192, 95–117. DOI: 10.1016/s0300-483x(03) 00305-6. Search in Google Scholar

88. Wan, X., Zhu, J.., Zhu, Y., Zhu, Y., Ma, X., Zheng, Y, et al., 2010: Rat ovarian follicle bioassay reveals adverse effects of cadmium chloride (CdCl2) exposure on follicle development and oocyte maturation. Toxicol. Industr. Health., 26, 9, 609–618. DOI: 10.1177/0748233710375949.10.1177/074823371037594920630984 Search in Google Scholar

89. Wan, L., Zhang, H., 2012: Cadmium toxicity: Effects on cytoskeleton, vesicular trafficking and cell wall reconstruction. Plant Signal. Behav., 7, 345–348.10.4161/psb.18992344391622499203 Search in Google Scholar

90. Wang, B., Shao, C., Li, Y., Tan, Y., Cai, L., 2012: Cadmium and its epigenetic effects. Curr. Med. Chem., 19, 2611–2620. DOI: 10.2174/092986712800492913.10.2174/09298671280049291322471978 Search in Google Scholar

91. Wang, Y., Wang, X., Wang, Y., Fan, R., Qiu, C., Zhong, S., et al., 2015: Effect of cadmium on cellular structure in mouse ovary. Ultrastruct. Pathol., 39, 324–328.10.3109/01913123.2015.102743626107819 Search in Google Scholar

92. World Health Organisation (WHO), 1992: Environmental Health Criteria 134, Cadmium. International Programme on Chemical Safety (IPCS), Geneva 4. 280 pp. Search in Google Scholar

93. Yang, X. J., Yao, H. J., Wang, Y. F., 2004: Advances in the research of oocyte apoptosis in mammals. Zoology, 39, 101–106. Search in Google Scholar

94. Yu, R. A., 2000: Cadmium and DNA damage, cancer gene expression as well as cell apoptosis. Overseas Med. Health Fascicl., 27, 359–363. Search in Google Scholar

95. Zenzes, M. T., Krishnan, S., Krishnan, B., Zhang, H., Casper, R. F., 1995: Cadmium accumulation in follicular fluid of women in in vitro fertilization-embryo transfer is higher in smokers. Fertil. Steril., 64, 599–603. DOI: 10.1016/s0015-0282(16)57799-1.10.1016/S0015-0282(16)57799-17641916 Search in Google Scholar

96. Zhang, W., Jia, H., 2007: Effect and mechanism of cadmium on the progesterone synthesis of ovaries. Toxicology, 239, 204–212. DOI: 10.1016/j.tox.2007. Search in Google Scholar

97. Zhang, W. C., Wu, Z. R., Li, H. Y., et al., 2002: Studies on the stimulating reaction of pituitary and ovary to sexual hormones in cadmium-induced rats. J. Health Toxicol., 16, 24–26. DOI: 10.1016/j.toxlet.2008. Search in Google Scholar

98. Zhang, W., Pang, F., Huang, Y., Yan, P., Lin, W., 2008: Cadmium exerts toxic effects on ovarian steroid hormone release in rats. Toxicol. Lett., 182, 18–23.10.1016/j.toxlet.2008.07.016 Search in Google Scholar

99. Zhang, W., Wu, T., Zhang, C., Luo, L., Xie, M., Huang, H., 2017: Cadmium exposure in newborn rats ovary induces developmental disorders of primordial follicles and the differential expression of SCF/c-kit gene. Toxicol. Lett., 280, 20–28. DOI: 10.1016/j.toxlet.2017. Search in Google Scholar

100. Zhang, T., Gao, X., Luo, X., Li, L., Ma, M., Zhu, Y., et al., 2019: The effects of long-term exposure to low doses of cadmium on the health of the next generation of mice. Chem. Biol. Interact., 1, 312. DOI: 10.1016/j.cbi.2019.108792.10.1016/j.cbi.2019.10879231491373 Search in Google Scholar

101. Zhang, W., Yang, J., Wang, J., Xia, P., Xu, Y., Jia, H., et al., 2007: Comparative studies on the increase of uterine weight and related mechanisms of cadmium and p-nonylphenol. Toxicology, 241, 84–91. DOI: 10.1016/j.tox.2007. Search in Google Scholar

102. Zhou, C., Zhang, X.,Chen, Y., Liu, X., Sun, Y., Xiong, B., 2019: Glutathione alleviates the cadmium exposure-caused porcine oocyte meiotic defects via eliminating the excessive ROS. Environ. Pollut., 255, 113194. DOI: 10.1016/j.envpol. 2019.113194. Search in Google Scholar

103. Zhu, J. Q., Liu, Y., Zhang, J. H., Liu, Y. F., Cao, J. Q., Huang, Z. T., et al., 2018: Cadmium exposure of female mice impairs the meiotic maturation of oocytes and subsequent embryonic development. Toxicol. Sci., 164, 289–299. DOI: 10.1093/toxsci/kfy089.10.1093/toxsci/kfy08929684212 Search in Google Scholar

Polecane artykuły z Trend MD

Zaplanuj zdalną konferencję ze Sciendo