8 Articles
Open Access | Jul 03, 2025
Design, synthesis, and evaluation of a novel fluorescent probe for competitive fluorescence polarization assay to screen galectin-8 inhibitors
Edvin Purić
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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, Marina Marinović
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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, Zala Kojek
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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, , Hakon Leffler
Section MIG (Microbiology, Immunology, Glycobiology), Department of Laboratory Medicine, Lund UniversityLund, Sweden
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, Ulf J. Nilsson
Department of Chemistry, Lund UniversityLund, Sweden
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, Marko Anderluh
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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and Janez Mravljak
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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Open Access | Jul 03, 2025
Optimization of 6-(trifluoromethyl)pyrimidine derivatives as TLR8 antagonists
Nika Strašek Benedik
University of Ljubljana, Faculty of Pharmacy, Department of Pharmaceutical ChemistryLjubljana, Slovenia
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, Valerij Talagayev
Freie Universität Berlin, Institute of Pharmacy, Pharmaceutical and Medicinal ChemistryBerlin, Germany
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, , , Izidor Sosič
University of Ljubljana, Faculty of Pharmacy, Department of Pharmaceutical ChemistryLjubljana, Slovenia
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, Günther Weindl
University of Bonn, Pharmaceutical Institute, Pharmacology and Toxicology SectionBonn, Germany
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, Gerhard Wolber
University of Ljubljana, Faculty of Pharmacy, Department of Pharmaceutical ChemistryLjubljana, Slovenia
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and Matej Sova
University of Ljubljana, Faculty of Pharmacy, Department of Pharmaceutical ChemistryLjubljana, Slovenia
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Open Access | Jul 03, 2025
Development and evaluation of novel InhA inhibitors inspired by thiadiazole and tetrahydropyran series of inhibitors
Martina Hrast Rambaher
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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, Nina Gradišek
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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, Rok Frlan
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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, Izidor Sosič
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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, Aljoša Bolje
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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, Jakob Kljun
University of Ljubljana, Faculty of Chemistry and Chemical TechnologyLjubljana, Slovenia
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, Martin Juhás
- University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
- Charles University, Faculty of Pharmacy in Hradec KrálovéCzech Republic
- University of Hradec Králové, Faculty of ScienceCzech Republic
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, Stanislav Gobec
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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and Stane Pajk
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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Open Access | Jul 03, 2025
Biochemical characteristics of the 6-nitro regioisomer of nitroxoline and its 1,2,3,4-tetrahydroquinoline analogues
Ana Mitrović
- Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
- Department of Biotechnology, Jožef Stefan InstituteLjubljana, Slovenia
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, Damijan Knez
Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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, Martina Hrast Rambaher
Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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, Jakob Kljun
Faculty of Chemistry and Chemical Technology, University of LjubljanaLjubljana, Slovenia
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, Janko Kos
- Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
- Department of Biotechnology, Jožef Stefan InstituteLjubljana, Slovenia
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, Stanislav Gobec
Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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and Izidor Sosič
Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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Open Access | Jul 03, 2025
Exploration of the chemical space of benzamide-based voltage-gated potassium channel Kv1.3 inhibitors
Marzia Fois
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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, Špela Pelcar
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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, , Heike Wulff
University of California, Davis Department of PharmacologyDavis CA, USA
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, Lucija Peterlin Mašič
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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and Tihomir Tomašič
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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Open Access | Jul 03, 2025
Impact of peroxide content in excipients and antioxidants on famotidine oxidative stability
, , Orcid profile and Orcid profile
Janez Ilaš
Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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and Stane Pajk
Faculty of Pharmacy, University of LjubljanaLjubljana, Slovenia
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Open Access | Jul 03, 2025
α-Heteroarylthiomethyl ketones: Small molecule inhibitors of 3CLpro
Damijan Knez
University of Ljubljana, Department of Pharmaceutical Chemistry, Faculty of PharmacyLjubljana, Slovenia
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, Matic Proj
University of Ljubljana, Department of Pharmaceutical Chemistry, Faculty of PharmacyLjubljana, Slovenia
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, Krištof Bozovičar
University of Ljubljana, Department of Pharmaceutical Biology, Faculty of PharmacyLjubljana, Slovenia
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and Stanislav Gobec
University of Ljubljana, Department of Pharmaceutical Chemistry, Faculty of PharmacyLjubljana, Slovenia
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Open Access | Jul 03, 2025
SARS-CoV-2 structural proteins affect the expression of IL-8 and TNF-α cytokines and APOBEC genes in human lung A549 and liver Huh-7 cells
Martina Bergant Marušič
University of Nova GoricaNova Gorica, Slovenia
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, , and Nika Lovšin
University of Ljubljana, Faculty of PharmacyLjubljana, Slovenia
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Volume 75 (2025)