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Acta Pharmaceutica

Volume 71 (2021): Issue 4 (December 2021)

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12 Articles
Open Access | Apr 03, 2021
Quality-by-design in pharmaceutical development: From current perspectives to practical applications
Béla Kovács

Béla Kovács

Department F1, Faculty of Pharmacy, George Emil Palade University of Medicine Pharmacy, Science, and Technology of Târgu MureșTârgu Mures, Romania
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Kovács, Béla
, 
Orsolya Péterfi

Orsolya Péterfi

Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy Science, and Technology of Târgu MureșTârgu Mures, Romania
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Péterfi, Orsolya
, 
Boglárka Kovács-Deák

Boglárka Kovács-Deák

Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy Science, and Technology of Târgu MureșTârgu Mures, Romania
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Kovács-Deák, Boglárka
, 
István Székely-Szentmiklósi

István Székely-Szentmiklósi

Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy Science, and Technology of Târgu MureșTârgu Mures, Romania
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Székely-Szentmiklósi, István
, 
Ibolya Fülöp

Ibolya Fülöp

Department F2, Faculty of Pharmacy, George Emil Palade University of Medicine Pharmacy, Science, and Technology of TârguTârgu Mures, Romania
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Fülöp, Ibolya
, 
László-István Bába

László-István Bába

Department F2, Faculty of Pharmacy, George Emil Palade University of Medicine Pharmacy, Science, and Technology of TârguTârgu Mures, Romania
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Bába, László-István
 and 
Francisc Boda

Francisc Boda

Department F1, Faculty of Pharmacy, George Emil Palade University of Medicine Pharmacy, Science, and Technology of Târgu MureșTârgu Mures, Romania
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Boda, Francisc
  
Open Access | Apr 03, 2021
Recent advancements to enhance the therapeutic efficacy of antiepileptic drugs
Fuquan Li

Fuquan Li

Zhangqiu District Maternal and Child Health HospitalJinan City, China
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Li, Fuquan
 and 
Akhilesh Vikram Singh

Akhilesh Vikram Singh

School of Epidemiology and Public Health, Datta Meghe Institute of Medical SciencesWardha, India
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Singh, Akhilesh Vikram
  
Open Access | Apr 03, 2021
New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation
Dima A. Sabbah

Dima A. Sabbah

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanJordan
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Sabbah, Dima A.
, 
Bara’a A. Al-Azaideh

Bara’a A. Al-Azaideh

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanJordan
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Al-Azaideh, Bara’a A.
, 
Wamidh H. Talib

Wamidh H. Talib

Department of Clinical Pharmacy and Therapeutics, Applied Science Private UniversityJordan
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Talib, Wamidh H.
, 
Rima Hajjo

Rima Hajjo

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanJordan
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Hajjo, Rima
, 
Kamal Sweidan

Kamal Sweidan

Department of Chemistry, The University of JordanJordan
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Sweidan, Kamal
, 
Aya M. Al-Zuheiri

Aya M. Al-Zuheiri

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanJordan
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Al-Zuheiri, Aya M.
, 
Ghassan Abu Sheikha

Ghassan Abu Sheikha

  • Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanJordan
  • Visiting Professor Scholar, Skaggs School of Pharmacy and Pharmaceutical Science, University of California
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Sheikha, Ghassan Abu
 and 
Sawsan Shraim

Sawsan Shraim

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanJordan
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Shraim, Sawsan
  
Open Access | Apr 03, 2021
Identification and pharmacokinetics of saponins in Rhizoma Anemarrhenae after oral administration to rats by HPLC-Q-TOF/MS and HPLC-MS/MS
Hai-Qiao Wang

Hai-Qiao Wang

Renji Hospital, School of Medicine, Shanghai Jiaotong UniversityShanghai, China
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Wang, Hai-Qiao
, 
Fen Lan

Fen Lan

Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical UniversityShanghai, China
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Lan, Fen
, 
Yi-Han Zhang

Yi-Han Zhang

Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical UniversityShanghai, China
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Zhang, Yi-Han
, 
Jin-Er Xia

Jin-Er Xia

Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical UniversityShanghai, China
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Xia, Jin-Er
, 
Xiao-Mei Gong

Xiao-Mei Gong

Department of Radiation Oncology, Shanghai Pulmonary Hospital, Tongji University, School of MedicineShanghai, China
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Gong, Xiao-Mei
 and 
Min Liu

Min Liu

Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical UniversityShanghai, China
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Liu, Min
  
Open Access | Apr 03, 2021
Upregulation of p53 by tannic acid treatment suppresses the proliferation of human colorectal carcinoma
Serdar Karakurt

Serdar Karakurt

Selcuk University, Faculty of Science, Department of BiochemistryKonya, Turkey
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Karakurt, Serdar
, 
Sinan Kandir

Sinan Kandir

Cukurova University, Ceyhan Faculty of Veterinary Medicine, Department of PhysiologyAdana, Turkey
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Kandir, Sinan
 and 
Çiğdem Gökçek-Saraç

Çiğdem Gökçek-Saraç

Faculty of Engineering, Department of Biomedical Engineering, Akdeniz UniversityAntalya, Turkey
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Gökçek-Saraç, Çiğdem
  
Open Access | Apr 03, 2021
Antioxidant and antihyperglycemic activities of Scorzonera cinerea radical leaves in streptozocin-induced diabetic rats
Mehmet Ali Temiz

Mehmet Ali Temiz

Programme of Medicinal and Aromatic Plants, Vocational School of Technical Sciences, Karamanoğlu Mehmetbey UniversityKaraman, Turkey
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Temiz, Mehmet Ali
  
Open Access | Apr 03, 2021
Determination of penicillamine, tiopronin and glutathione in pharmaceutical formulations by kinetic spectrophotometry
Lea Kukoc-Modun

Lea Kukoc-Modun

Department of Analytical Chemistry, Faculty of Chemistry and Technology, University of SplitSplit, Croatia
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Kukoc-Modun, Lea
, 
Maja Biocic

Maja Biocic

Department of Analytical Chemistry, Faculty of Chemistry and Technology, University of SplitSplit, Croatia
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Biocic, Maja
 and 
Njegomir Radić

Njegomir Radić

Department of Analytical Chemistry, Faculty of Chemistry and Technology, University of SplitSplit, Croatia
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Radić, Njegomir
  
Open Access | Apr 03, 2021
Piperazine sulfonamides as DPP-IV inhibitors: Synthesis, induced-fit docking and in vitro biological evaluation
Reema Abu Khalaf

Reema Abu Khalaf

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanAmman, Jordan
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Khalaf, Reema Abu
, 
Ebtisam Alwarafi

Ebtisam Alwarafi

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanAmman, Jordan
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Alwarafi, Ebtisam
 and 
Dima Sabbah

Dima Sabbah

Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of JordanAmman, Jordan
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Sabbah, Dima
  
Open Access | Apr 03, 2021
Anticancer effects of 7,8-dihydromethysticin in human leukemia cells are mediated via cell-cycle dysregulation, inhibition of cell migration and invasion and targeting JAK/STAT pathway
Yi Xiao

Yi Xiao

Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, China
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Xiao, Yi
, 
Taoran Deng

Taoran Deng

Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, China
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Deng, Taoran
, 
Lijun Jiang

Lijun Jiang

Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, China
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Jiang, Lijun
 and 
Di Wang

Di Wang

Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyWuhan, China
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Wang, Di
  
Open Access | Apr 03, 2021
Propolis – quality analysis and use in topical formulations
Kristina Ramanauskiene

Kristina Ramanauskiene

Department of Clinical Pharmacy, Lithuanian University of Health SciencesKaunas, Lithuania
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Ramanauskiene, Kristina
, 
Asta Marija Inkeniene

Asta Marija Inkeniene

Department of Clinical Pharmacy, Lithuanian University of Health SciencesKaunas, Lithuania
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Inkeniene, Asta Marija
, 
Kristina Perminaite

Kristina Perminaite

Department of Clinical Pharmacy, Lithuanian University of Health SciencesKaunas, Lithuania
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Perminaite, Kristina
, 
Modestas Zilius

Modestas Zilius

Department of Clinical Pharmacy, Lithuanian University of Health SciencesKaunas, Lithuania
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Zilius, Modestas
 and 
Daiva Majiene

Daiva Majiene

Neuroscience Institute, Lithuanian University of Health SciencesKaunas, Lithuania
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Majiene, Daiva
  
Open Access | Apr 03, 2021
Pinocembrin flavanone inhibits cell viability in PC-3 human prostate cancer by inducing cellular apoptosis, ROS production and cell cycle arrest
Linhai Shao

Linhai Shao

Department of Urology, Hanzhong Central HospitalChina
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Shao, Linhai
, 
Yajun Shao

Yajun Shao

Department of Ultrasound, Xi’an NO.1 HospitalChina
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Shao, Yajun
 and 
Yu Yuan

Yu Yuan

Department of Ophthalmology, Hanzhong Central HospitalChina
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Yuan, Yu
  
Open Access | Apr 03, 2021
Pharmacokinetics study of a supersaturatable self-microemulsifying drug delivery system for ellagic acid by UHPLC-Q-TOF-MS
Jinglong Wang

Jinglong Wang

College of Food Sciences and Pharmaceutical Engineering, Zaozhuang University277160, China
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Wang, Jinglong
, 
Liqun Fan

Liqun Fan

College of Food Sciences and Pharmaceutical Engineering, Zaozhuang University277160, China
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Fan, Liqun
, 
Lihua Zhang

Lihua Zhang

College of Food Sciences and Pharmaceutical Engineering, Zaozhuang University277160, China
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Zhang, Lihua
, 
Dandan Zheng

Dandan Zheng

College of Food Sciences and Pharmaceutical Engineering, Zaozhuang University277160, China
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Zheng, Dandan
, 
Yingzi Wang

Yingzi Wang

School of Chinese Materia Medica, Beijing University of Traditional Chinese MedicineBeijing, China
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Wang, Yingzi
, 
Xiao Sun

Xiao Sun

School of Pharmaceutical Sciences, Shandong UniversityJinan, China
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Sun, Xiao
 and 
Yonghui Ji

Yonghui Ji

College of Food Sciences and Pharmaceutical Engineering, Zaozhuang University277160, China
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Ji, Yonghui
  

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