Puffing regime | Puff count | Volume (mL/min) | Nicotine (mg/cig) | ACM (mg/cig) | Water (mg/cig) | Nicotine (mg/puff) | ACM (mg/puff) | Water (mg/puff) |
---|---|---|---|---|---|---|---|---|
55 / 3 / 30 | 60 | 110 | 1.2 | 73.2 | 12.5 | 0.020 | 1.22 | 0.21 |
55 / 3 / 60 | 60 | 55 | 1.0 | 63.9 | 11.0 | 0.016 | 1.07 | 0.18 |
Sample | Total PG | Total nicotine | Total glycerin | Total water |
---|---|---|---|---|
Lab 1-Rechargeable | 47–48 | 1.2–1.2 | 26–27 | 11–13 |
Lab 2-Disposable | 56–58 | 1.8–1.9 | 28–29 | 8–11 |
Lab 2-Rechargeable | 57–59 | 1.8–1.9 | 28–29 | 8–12 |
Lab 3-Disposable | NA |
1.6–1.6 | 71–76 | 20–20 |
Lab 3-Rechargeable | NA | 1.3–1.4 | 72–76 | 15–16 |
Lab 4-Disposable | 42–47 | 1.0–1.2 | 33–39 | 15–18 |
Lab 4-Rechargeable | 34–41 | 1.4–1.5 | 41–44 | 11–13 |
Lab 1-Rechargeable | 3 % | 2 % | 4 % | 21 % |
Lab 2-Disposable | 4 % | 4 % | 5 % | 33 % |
Lab 2-Rechargeable | 3 % | 3 % | 4 % | 32 % |
Lab 3-Disposable | NA | 1 % | 6 % | 3 % |
Lab 3-Rechargeable | NA | 2 % | 7 % | 9 % |
Lab 4-Disposable | 10 % | 22 % | 16 % | 21 % |
Lab 4-Rechargeable | 19 % | 8 % | 6 % | 17 % |
Sample | Profile | Puff numbers |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
0–25 | 26–50 | 51–75 | 76–100 | 101–125 | 126–150 | 151–175 | 176–200 | 201–225 | 226–250 | 251–275 | ||
Lab 2-Disposable | 55 / 3 / 30 / Sq | 19 | 22 | 24 | 29 | 34 | ||||||
55 / 4 / 30 / Sq | 6 | 6 | 5 | 7 | ||||||||
70 / 3 / 30 / Sq | 6 | 9 | 9 | 15 | ||||||||
70 / 4 / 30 / Sq | 6 | 6 | 7 | 7 | ||||||||
Lab 3-Disposable | 55 / 3 / 30 / Sq | 6 | 8 | 9 | 9 | 11 | 13 | 9 | 9 | 19 | ||
55 / 4 / 30 / Sq | 12 | 13 | 11 | 12 | 12 | 13 | 15 | |||||
70 / 3 / 30 / Sq | 8 | 11 | 14 | 17 | 18 | 20 | 15 | 18 | 18 | |||
70 / 4 / 30 / Sq | 7 | 11 | 12 | 13 | 17 | 18 | 19 | |||||
Lab 4-Disposable | 55 / 3 / 30 / Sq | 10 | 8 | 6 | 8 | 6 | 8 | 5 | 5 | 9 | ||
55 / 4 / 30 / Sq | 6 | 6 | 8 | 5 | 8 | 7 | 4 | 5 | ||||
70 / 3 / 30 / Sq | 3 | 5 | 4 | 4 | 4 | 4 | 6 | 5 | 22 | 8 | 20 | |
70 / 4 / 30 / Sq | 13 | 13 | 12 | 11 | 7 | 12 | 14 |
Sample | Profile | Puff numbers |
||||||||
---|---|---|---|---|---|---|---|---|---|---|
0–25 | 26–50 | 51–75 | 76–100 | 101–125 | 126–150 | 151–175 | 176–200 | 201–225 | ||
Lab 1-Rechargeable | 55 / 3 / 30 / Sq | 7 | 8 | 9 | 9 | 7 | 10 | 9 | 9 | |
55 / 4 / 30 / Sq | 7 | 10 | 11 | 11 | 11 | 11 | ||||
70 / 3 / 30 / Sq | 10 | 8 | 8 | 10 | 8 | 9 | 8 | 7 | ||
70 / 4 / 30 / Sq | 14 | 14 | 14 | 14 | 14 | 11 | ||||
Lab 2-Rechargeable | 55 / 3 / 30 / Sq | 17 | 17 | 20 | 18 | 18 | 18 | 16 | 13 | |
55 / 4 / 30 / Sq | 11 | 7 | 6 | 5 | 7 | 9 | ||||
70 / 3 / 30 / Sq | 18 | 18 | 18 | 18 | 19 | 19 | 20 | 24 | 6 | |
70 / 4 / 30 / Sq | 14 | 11 | 9 | 9 | 9 | 6 | ||||
Lab 3-Rechargeable | 55 / 3 / 30 / Sq | 11 | 16 | 17 | 26 | |||||
55 / 4 / 30 / Sq | 10 | 8 | 7 | |||||||
70 / 3 / 30 / Sq | 11 | 12 | 13 | 17 | ||||||
70 / 4 / 30 / Sq | 11 | 7 | 8 | |||||||
Lab 4-Rechargeable | 55 / 3 / 30 / Sq | 6 | 5 | 7 | 6 | |||||
55 / 4 / 30 / Sq | 7 | 6 | 5 | 4 | ||||||
70 / 3 / 30 / Sq | 7 | 6 | 7 | 5 | ||||||
70 / 4 / 30 / Sq | 7 | 7 | 5 |
Lab 1-Rechargeable | Lab 2-Disposable | Lab 2-Rechargeable | Lab 3-Disposable | Lab 3-Rechargeable | Lab 4-Disposable | Lab 4-Rechargeable | |
---|---|---|---|---|---|---|---|
Test 1 | 1.0 | 1.0 | 1.0 | 1.1 | 1.0 | 1.0 | 0.9 |
Test 2 | 0.4 | 1.0 | 1.0 | 1.1 | 1.1 | 1.0 | 1.0 |
Test 3 | 1.0 | 1.0 | 1.0 | 1.1 | 1.1 | 1.0 | 0.9 |
Test 4 | 1.0 | 1.0 | 1.0 | 1.1 | 1.0 | 1.0 | 1.0 |
Sample ID | Sample Description |
---|---|
Lab 1-Rechargeable | Rechargeable product tested by Laboratory 1 |
Lab 2-Rechargeable | Rechargeable product tested by Laboratory 2 |
Lab 2-Disposable | Disposable product tested by Laboratory 2 |
Lab 3-Rechargeable | Rechargeable product tested by Laboratory 3 |
Lab 3-Disposable | Disposable product tested by Laboratory 3 |
Lab 4-Rechargeable | Rechargeable product tested by Laboratory 4 |
Lab 4-Disposable | Disposable product tested by Laboratory 4 |
Sample | Regime 1 | Regime 2 | Regime 3 | Regime 4 | Range |
|
---|---|---|---|---|---|---|
Lab 1-Rechargeable | Avg | 647 | 677 | 621 | 629 | 9% |
SD | 46 | 60 | 45 | 74 | ||
%RSD | 7% | 9% | 7% | 12% | ||
Lab 2-Rechargeable | Avg | 253 | 289 | 226 | 279 | 24% |
SD | 60 | 14 | 25 | 13 | ||
%RSD | 24% | 5% | 11% | 5% | ||
Lab 2-Disposable | Avg | 537 | 590 | 542 | 611 | 13% |
SD | 79 | 30 | 79 | 48 | ||
%RSD | 15% | 5% | 15% | 8% | ||
Lab 3-Rechargeable | Avg | 377 | 416 | 370 | 369 | 12% |
SD | 35 | 52 | 50 | 44 | ||
%RSD | 9% | 13% | 14% | 12% | ||
Lab 3-Disposable | Avg | 234 | 267 | 268 | 270 | 14% |
SD | 46 | 30 | 39 | 22 | ||
%RSD | 20% | 11% | 14% | 8% | ||
Lab 4-Rechargeable | Avg | 258 | 303 | 265 | 284 | 16% |
SD | 9 | 17 | 17 | 11 | ||
%RSD | 4% | 6% | 6% | 4% | ||
Lab 4-Disposable | Avg | 891 | 924 | 870 | 942 | 8% |
SD | 118 | 70 | 111 | 162 | ||
%RSD | 13% | 8% | 13% | 17% |
Regime | Code | Puff volume (mL) | Duration (s) | Shape | Frequency | Mean flow (mL/s) |
---|---|---|---|---|---|---|
Regime 1 | 55 / 3 / 30 / Sq | 55 | 3 | Square | Every 30 s | 18.3 |
Regime 2 | 55 / 4 / 30 / Sq | 55 | 4 | Square | Every 30 s | 13.8 |
Regime 3 | 70 / 3 / 30 / Sq | 70 | 3 | Square | Every 30 s | 23.3 |
Regime 4 | 70 / 4 / 30 / Sq | 70 | 4 | Square | Every 30 s | 17.5 |
ISO-like |
35 / 2 / 60 / B | 35 | 2 | Bell | Every 60 s | 17.5 |
CI-like |
55 / 2 / 30 / B | 55 | 2 | Bell | Every 30 s | 27.5 |
Pad | Profile |
||
---|---|---|---|
Bell-shaped | Triangle-shaped | Square-shaped | |
1st 50 puffs | 0.48 ± 0.12 | 0.58 ± 0.19 | 0.69 ± 0.14 |
2nd 50 puffs | 0.38 ± 0.11 | 0.33 ± 0.12 | 0.54 ± 0.14 |
3rd 50 puffs | 0.24 ± 0.10 | 0.28 ± 0.10 | 0.34 ± 0.11 |
4th 50 puffs | 0.29 ± 0.08 | 0.24 ± 0.09 | 0.38 ± 0.10 |
5th 50 puffs | 0.25 ± 0.07 | 0.22 ± 0.07 | 0.38 ± 0.07 |
6th 50 puffs | 0.20 ± 0.06 | 0.19 ± 0.07 | 0.30 ± 0.07 |
7th 50 puffs | 0.19 ± 0.06 | 0.19 ± 0.06 | 0.28 ± 0.06 |
8th 50 puffs | 0.17 ± 0.05 | 0.15 ± 0.05 | 0.23 ± 0.05 |
400 puffs total | 2.19 ± 0.64 | 2.17 ± 0.74 | 3.14 ± 0.69 |
Puff blocks | 35 mL, 1 day | 55 mL, 1 day | 65 mL, 1 day | 35 mL, 1 week | 55 mL, 1 week | 65 mL, 1 week |
---|---|---|---|---|---|---|
1st 90 puffs | 116.9 | 133.5 | 140.9 | 115.8 | 130.4 | 137.9 |
2nd 90 puffs | 101.2 | 109.6 | 115.6 | 100.1 | 107.9 | 116.3 |
3rd 90 puffs | 88.9 | 94.2 | 97.4 | 84.7 | 89.4 | 97.8 |
4th 90 puffs | 71.7 | 80.0 | 80.8 | 72.8 | 76.0 | 83.5 |
Total | 378.6 | 417.2 | 434.7 | 373.3 | 403.7 | 435.5 |