Disorders in blood circulation as a probable cause of death in dogs infected with Babesia canis

1Adaszek L., Górna M., Klimiuk P., Kalinowski M., Winiarczyk S.: A presumptive case of cerebral babesiosis in a dog in Poland caused by a virulent Babesia canis strain. Tierärztl Prax Ausg K Kleintiere Heimtiere 2012, 40, 367–371, doi: 10.1055/s-0038-1623660. Adaszek L. Górna M. Klimiuk P. Kalinowski M. Winiarczyk S. A presumptive case of cerebral babesiosis in a dog in Poland caused by a virulent Babesia canis strain Tierärztl Prax Ausg K Kleintiere Heimtiere 2012 40 367 371 10.1055/s-0038-1623660Open DOISearch in Google Scholar

2Barić Rafaj R., Kuleš J., Selanec J., Vrkić N., Zovko V., Zupančič M., Trampuš Bakija A., Matijatko V., Crnogaj M., Mrljak V.: Markers of Coagulation Activation, Endothelial Stimulation, and Inflammation in Dogs with Babesiosis. J Vet Intern Med 2013, 27, 1172–1178, doi: 10.1111/jvim.12146. Barić Rafaj R. Kuleš J. Selanec J. Vrkić N. Zovko V. Zupančič M. Trampuš Bakija A. Matijatko V. Crnogaj M. Mrljak V. Markers of Coagulation Activation, Endothelial Stimulation, and Inflammation in Dogs with Babesiosis J Vet Intern Med 2013 27 1172 1178 10.1111/jvim.1214623875771Open DOISearch in Google Scholar

3Bartnicki M., Łyp P., Dębiak P., Staniec M., Winiarczyk S., Buczek K., Adaszek Ł.: Cardiac disorders in dogs infected with Babesia canis. Pol J Vet Sci 2017, 20, 573–581, doi: 10.1515/pjvs-2017-0070. Bartnicki M. Łyp P. Dębiak P. Staniec M. Winiarczyk S. Buczek K. Adaszek Ł. Cardiac disorders in dogs infected with Babesia canis Pol J Vet Sci 2017 20 573 581 10.1515/pjvs-2017-007029166283Open DOISearch in Google Scholar

4Bonfanti U., Zini E., Minetti E., Zatelli A.: Free light-chain proteinuria and normal renal histopathology and function in 11 dogs exposed to Leishmania infantum Ehrlichia canis, and Babesia canis. J Vet Intern Med 2004, 18, 618–624, doi: 10.1111/j.1939-1676.2004.tb02596.x. Bonfanti U. Zini E. Minetti E. Zatelli A. Free light-chain proteinuria and normal renal histopathology and function in 11 dogs exposed to Leishmania infantum Ehrlichia canis, and Babesia canis J Vet Intern Med 2004 18 618 624 10.1111/j.1939-1676.2004.tb02596.xOpen DOISearch in Google Scholar

5Bosman A.M., Oosthuizen M.C., Venter E.H., Steyl J.C.A., Gous T.A., Penzhorn B.L.: Babesia lengau associated with cerebral and haemolytic babesiosis in two domestic cats. Parasit Vectors 2013, 6, 128, doi: 10.1186/1756-3305-6-128. Bosman A.M. Oosthuizen M.C. Venter E.H. Steyl J.C.A. Gous T.A. Penzhorn B.L. Babesia lengau associated with cerebral and haemolytic babesiosis in two domestic cats Parasit Vectors 2013 6 128 10.1186/1756-3305-6-128365274623634743Open DOISearch in Google Scholar

6Bouyssou S., Specchi S., Desquilbet L., Pey P.: Radiographic appearance of presumed noncardiogenic pulmonary edema and correlation with the underlying cause in dogs and cats. Vet Radiol Ultrasound 2017, 58, 259–265, doi: 10.1111/vru.12468. Bouyssou S. Specchi S. Desquilbet L. Pey P. Radiographic appearance of presumed noncardiogenic pulmonary edema and correlation with the underlying cause in dogs and cats Vet Radiol Ultrasound 2017 58 259 265 10.1111/vru.1246828005303Open DOISearch in Google Scholar

7Buob S., Johnston A.N., Webster C.R.L.: Portal Hypertension: Pathophysiology, Diagnosis, and Treatment. J Vet Intern Med 2011, 25, 169–186, doi: 10.1111/j.1939-1676.2011.00691.x. Buob S. Johnston A.N. Webster C.R.L. Portal Hypertension: Pathophysiology, Diagnosis, and Treatment J Vet Intern Med 2011 25 169 186 10.1111/j.1939-1676.2011.00691.x21382073Open DOISearch in Google Scholar

8Cullen J.M.: Liver, Biliary System, and Exocrine Pancreas. In: Pathologic Basis of Veterinary Disease, edited by M.D. McGavin, J.F. Zachary, Mosby Elsevier, St. Louis, 2007, pp. 393–461. Cullen J.M. Liver, Biliary System, and Exocrine Pancreas In Pathologic Basis of Veterinary Disease edited by McGavin M.D. Zachary J.F. Mosby Elsevier, St. Louis 2007 pp 393 461Search in Google Scholar

9Damas J., Remacle-Volon G., Adam A.: Mechanism of the congestion of lymph nodes induced by ellagic acid in rats. Agents Actions 1987, 22, 202–208, doi: 10.1007/BF02009047. Damas J. Remacle-Volon G. Adam A. Mechanism of the congestion of lymph nodes induced by ellagic acid in rats Agents Actions 1987 22 202 208 10.1007/BF020090473445816Open DOISearch in Google Scholar

10Damman K., Navis G., Smilde T.D.J., Voors A.A., van der Bij W., van Veldhuisen D.J., Hillege H.L.: Decreased cardiac output, venous congestion and the association with renal impairment in patients with cardiac dysfunction. Eur J Heart Fail 2007, 9, 872–878, doi: 10.1016/j.ejheart.2007.05.010. Damman K. Navis G. Smilde T.D.J. Voors A.A. van der Bij W. van Veldhuisen D.J. Hillege H.L. Decreased cardiac output, venous congestion and the association with renal impairment in patients with cardiac dysfunction Eur J Heart Fail 2007 9 872 878 10.1016/j.ejheart.2007.05.01017586090Open DOISearch in Google Scholar

11Daste T., Lucas M.N., Aumann M.: Cerebral babesiosis and acute respiratory distress syndrome in a dog. J Vet Emerg Crit Care 2013, 23, 615–623, doi: 10.1111/vec.12114. Daste T. Lucas M.N. Aumann M. Cerebral babesiosis and acute respiratory distress syndrome in a dog J Vet Emerg Crit Care 2013 23 615 623 10.1111/vec.1211424238090Open DOISearch in Google Scholar

12Dvir E., Lobetti R.G., Jacobson L.S., Pearson J., Becker P.J.: Electrocardiographic changes and cardiac pathology in canine babesiosis. J Vet Cardiol 2004, 6, 15–23, doi: 10.1016/S1760-2734(06)70060-1. Dvir E. Lobetti R.G. Jacobson L.S. Pearson J. Becker P.J. Electrocardiographic changes and cardiac pathology in canine babesiosis J Vet Cardiol 2004 6 15 23 10.1016/S1760-2734(06)70060-1Open DOISearch in Google Scholar

13Dvorin J.D.: Getting Your Head around Cerebral Malaria. Cell Host Microbe 2017, 22, 586–588, doi: 10.1016/j.chom. 2017.10.017. Dvorin J.D. Getting Your Head around Cerebral Malaria Cell Host Microbe 2017 22 586 588 10.1016/j.chom.2017.10.017Open DOISearch in Google Scholar

14Fanelli V., Vlachou A., Ghannadian S., Simonetti U., Slutsky A.S., Zhang H.: Acute respiratory distress syndrome: new definition, current and future therapeutic options. J Thorac Dis 2013, 5, 326–334, doi: 10.3978/j.issn.2072-1439.2013.04.05. Fanelli V. Vlachou A. Ghannadian S. Simonetti U. Slutsky A.S. Zhang H. Acute respiratory distress syndrome: new definition, current and future therapeutic options J Thorac Dis 2013 5 326 334 10.3978/j.issn.2072-1439.2013.04.05Open DOISearch in Google Scholar

15Fraga E., Barreiro J.D., Goicoa A., Espino L., Fraga G., Barreiro A.: Abdominal ultrasonographic findings in dogs naturally infected with babesiosis. Vet Radiol Ultrasound 2011, 52, 323–329, doi: 10.1111/j.1740-8261.2010.01775.x. Fraga E. Barreiro J.D. Goicoa A. Espino L. Fraga G. Barreiro A. Abdominal ultrasonographic findings in dogs naturally infected with babesiosis Vet Radiol Ultrasound 2011 52 323 329 10.1111/j.1740-8261.2010.01775.xOpen DOISearch in Google Scholar

16Goddard A., Leisewitz A.L., Kjelgaard-Hansen M., Kristensen A.T., Schoeman J.P.: Excessive Pro-Inflammatory Serum Cytokine Concentrations in Virulent Canine Babesiosis. PLoS One 2016, 11, e0150113, doi: 10.1371/journal.pone.0150113. Goddard A. Leisewitz A.L. Kjelgaard-Hansen M. Kristensen A.T. Schoeman J.P. Excessive Pro-Inflammatory Serum Cytokine Concentrations in Virulent Canine Babesiosis PLoS One 2016 11 e0150113 10.1371/journal.pone.0150113Open DOISearch in Google Scholar

17Goddard A., Leisewitz A.L., Kristensen A.T., Schoeman J.P.: Platelet indices in dogs with Babesia rossi infection. Vet Clin Pathol 2015, 44, 493–497, doi: 10.1111/vcp.12306. Goddard A. Leisewitz A.L. Kristensen A.T. Schoeman J.P. Platelet indices in dogs with Babesia rossi infection Vet Clin Pathol 2015 44 493 497 10.1111/vcp.12306Open DOISearch in Google Scholar

18Habela M.A., Reina D., Navarrete I., Redondo E., Hernández S.: Histopathological changes in sheep experimentally infected with Babesia ovis. Vet Parasitol 1991, 38, 1–12, doi: 10.1016/0304-4017(91)90002-D. Habela M.A. Reina D. Navarrete I. Redondo E. Hernández S. Histopathological changes in sheep experimentally infected with Babesia ovis Vet Parasitol 1991 38 1 12 10.1016/0304-4017(91)90002-DOpen DOISearch in Google Scholar

19Irwin P.J.: Canine babesiosis: from molecular taxonomy to control. Parasit. Vectors 2009, 2 (Suppl 1), S4, doi: 10.1186/1756-3305-2-S1-S4. Irwin P.J. Canine babesiosis: from molecular taxonomy to control Parasit. Vectors 2009 2 Suppl 1 S4 10.1186/1756-3305-2-S1-S4267939619426443Open DOISearch in Google Scholar

20Irwin P.J., Hutchinson G.W.: Clinical and pathological findings of Babesia infection in dogs. Aust Vet J 1991, 68, 204–209, doi: 10.1111/j.1751-0813.1991.tb03194.x. Irwin P.J. Hutchinson G.W. Clinical and pathological findings of Babesia infection in dogs Aust Vet J 1991 68 204 209 10.1111/j.1751-0813.1991.tb03194.x1888313Open DOISearch in Google Scholar

21Jacobson L.S.: The South African form of severe and complicated canine babesiosis: Clinical advances 1994–2004. Vet Parasitol 2006, 138, 126–139, doi: 10.1016/j.vetpar.2006.01.047. Jacobson L.S. The South African form of severe and complicated canine babesiosis: Clinical advances 1994–2004 Vet Parasitol 2006 138 126 139 10.1016/j.vetpar.2006.01.04716503090Open DOISearch in Google Scholar

22Jacobson L.S., Clark I.A.: The pathophysiology of canine babesiosis: new approaches to an old puzzle. J S Afr Vet Assoc 1994, 65, 134–145, doi: 10520/AJA00382809_1498. Jacobson L.S. Clark I.A. The pathophysiology of canine babesiosis: new approaches to an old puzzle J S Afr Vet Assoc 1994 65 134 145 10520/AJA00382809_1498Open DOISearch in Google Scholar

23Joubert K.E., Oglesby P.A., Downie J., Serfontein T.: Abdominal compartment syndrome in a dog with babesiosis. J Vet Emerg Crit Care 2007, 17, 184–190, doi: 10.1111/j.1476-4431.2006.00219.x. Joubert K.E. Oglesby P.A. Downie J. Serfontein T. Abdominal compartment syndrome in a dog with babesiosis J Vet Emerg Crit Care 2007 17 184 190 10.1111/j.1476-4431.2006.00219.xOpen DOISearch in Google Scholar

24Kuroda T., Hirooka M., Koizumi M., Ochi H., Hisano Y., Bando K., Matsuura B., Kumagi T., Hiasa Y.: Pancreatic congestion in liver cirrhosis correlates with impaired insulin secretion. J Gastroenterol 2015, 50, 683–693, doi: 10.1007/s00535-014-1001-8. Kuroda T. Hirooka M. Koizumi M. Ochi H. Hisano Y. Bando K. Matsuura B. Kumagi T. Hiasa Y. Pancreatic congestion in liver cirrhosis correlates with impaired insulin secretion J Gastroenterol 2015 50 683 693 10.1007/s00535-014-1001-825283134Open DOISearch in Google Scholar

25Leisewitz A., Goddard A., De Gier J., Van Engelshoven J., Clift S., Thompson P., Schoeman J.P.: Disease severity and blood cytokine concentrations in dogs with natural Babesia rossi infection. Parasite Immunol 2019, 41, e12630, doi: 10.1111/ pim.12630. Leisewitz A. Goddard A. De Gier J. Van Engelshoven J. Clift S. Thompson P. Schoeman J.P. Disease severity and blood cytokine concentrations in dogs with natural Babesia rossi infection Parasite Immunol 2019 41 e12630 10.1111/pim.1263031063593Open DOISearch in Google Scholar

26Leisewitz A., Turner G., Clift S., Pardini A.: The neuropathology of canine cerebral babesiosis compared to human cerebral malaria. Malaria J 2014, 13 (Suppl 1), P55, doi: 10.1186/1475-2875-13-S1-P55. Leisewitz A. Turner G. Clift S. Pardini A. The neuropathology of canine cerebral babesiosis compared to human cerebral malaria Malaria J 2014 13 Suppl 1 P55 10.1186/1475-2875-13-S1-P55Open DOISearch in Google Scholar

27Lobetti R.G., Reyers F., Nesbit J.W.: The comparative role of haemoglobinaemia and hypoxia in the development of canine babesial nephropathy. J S Afr Vet Assoc 1996, 67, 188–198, doi: 10520/AJA00382809_1681. Lobetti R.G. Reyers F. Nesbit J.W. The comparative role of haemoglobinaemia and hypoxia in the development of canine babesial nephropathy J S Afr Vet Assoc 1996 67 188 198 10520/AJA00382809_1681Open DOISearch in Google Scholar

28López A.: Respiratory System. In: Pathologic Basis of Veterinary Disease, edited by M.D. McGavin, J.F. Zachary, Mosby Elsevier, St. Louis, 2007, pp. 463–558. López A. Respiratory System In Pathologic Basis of Veterinary Disease edited by McGavin M.D. Zachary J.F. Mosby Elsevier, St. Louis 2007 pp 463 558Search in Google Scholar

29Máthé A., Dobos-Kovács M., Vörös K.: Histological and ultrastructural studies of renal lesions in Babesia canis infected dogs treated with imidocarb. Acta Vet Hung 2007, 55, 511–523, doi: 10.1556/AVet.55.2007.4.10. Máthé A. Dobos-Kovács M. Vörös K. Histological and ultrastructural studies of renal lesions in Babesia canis infected dogs treated with imidocarb Acta Vet Hung 2007 55 511 523 10.1556/AVet.55.2007.4.1018277710Open DOISearch in Google Scholar

30Máthé A., Vörös K., Németh T., Biksi I., Hetyey C., Manczur F., Tekes L.: Clinicopathological changes and effect of imidocarb therapy in dogs experimentally infected with Babesia canis. Acta Vet Hung 2006, 54, 19–33, doi: 10.1556/AVet.54.2006.1.3. Máthé A. Vörös K. Németh T. Biksi I. Hetyey C. Manczur F. Tekes L Clinicopathological changes and effect of imidocarb therapy in dogs experimentally infected with Babesia canis Acta Vet Hung 2006 54 19 33 10.1556/AVet.54.2006.1.316613023Open DOISearch in Google Scholar

31Mohmand H., Goldfarb S.: Renal Dysfunction Associated with Intra-abdominal Hypertension and the Abdominal Compartment Syndrome. J Am Soc Nephrol 2011, 22, 615–621, doi: 10.1681/ASN.2010121222. Mohmand H. Goldfarb S. Renal Dysfunction Associated with Intra-abdominal Hypertension and the Abdominal Compartment Syndrome J Am Soc Nephrol 2011 22 615 621 10.1681/ASN.201012122221310818Open DOISearch in Google Scholar

32Möhr A.J., Lobetti R.G., van der Lugt J.J.: Acute pancreatitis: a newly recognised potential complication of canine babesiosis. J S Afr Vet Assoc 2000, 71, 232–239, doi: 10.4102/jsava.v71i4.721. Möhr A.J. Lobetti R.G. van der Lugt J.J. Acute pancreatitis: a newly recognised potential complication of canine babesiosis J S Afr Vet Assoc 2000 71 232 239 10.4102/jsava.v71i4.72111212934Open DOISearch in Google Scholar

33Newman S.J., Confer A.W., Panciera R.J.: Urinary System. In: Pathologic Basis of Veterinary Disease, edited by M.D. McGavin, J.F. Zachary, Mosby Elsevier, St. Louis, 2007, pp. 613–691. Newman S.J. Confer A.W. Panciera R.J. Urinary System In Pathologic Basis of Veterinary Disease edited by McGavin M.D. Zachary J.F. Mosby Elsevier, St. Louis 2007 pp 613 691Search in Google Scholar

34Rodrigues A., Rech R.R., de Barros R.R., Fighera R.A., de Barros C.S.L.: Cerebral babesiosis in cattle: 20 cases. Cienc Rural 2005, 35, 121–125, doi: 10.1590/S0103-84782005000100019. Rodrigues A. Rech R.R. de Barros R.R. Fighera R.A. de Barros C.S.L. Cerebral babesiosis in cattle: 20 cases Cienc Rural 2005 35 121 125 10.1590/S0103-84782005000100019Open DOISearch in Google Scholar

35Ruiz de Gopegui R., Peñalba B., Goicoa A., Espada Y., Fidalgo L.E., Espino L.: Clinico-pathological findings and coagulation disorders in 45 cases of canine babesiosis in Spain. Vet J 2007, 174, 129–132, doi: 10.1016/j.tvjl.2006.05.017 Ruiz de Gopegui R. Peñalba B. Goicoa A. Espada Y. Fidalgo L.E. Espino L. Clinico-pathological findings and coagulation disorders in 45 cases of canine babesiosis in Spain Vet J 2007 174 129 132 10.1016/j.tvjl.2006.05.01716901737Open DOISearch in Google Scholar

36Rymaszewska A., Adamska M.: Molecular evidence of vector-borne pathogens coinfecting dogs from Poland. Acta Vet Hung 2011, 59, 215–223, doi: 10.1556/AVet.2011.008. Rymaszewska A. Adamska M. Molecular evidence of vector-borne pathogens coinfecting dogs from Poland Acta Vet Hung 2011 59 215 223 10.1556/AVet.2011.00821665575Open DOISearch in Google Scholar

37Shimada S., Hirose T., Takahashi C., Sato E., Kinugasa S., Ohsaki Y., Kisu K., Sato S., Ito S., Mori T.: Pathophysiological and molecular mechanisms involved in renal congestion in a novel rat model. Sci Rep 2018, 8, 16808, doi: 10.1038/s41598-018-35162-4 Shimada S. Hirose T. Takahashi C. Sato E. Kinugasa S. Ohsaki Y. Kisu K. Sato S. Ito S. Mori T. Pathophysiological and molecular mechanisms involved in renal congestion in a novel rat model Sci Rep 2018 8 16808 10.1038/s41598-018-35162-4623588530429498Open DOISearch in Google Scholar

38Sun L.Y., Wijeysundera D.N., Tait G.A., Beattie W.S.: Association of Intraoperative Hypotension with Acute Kidney Injury after Elective Noncardiac Surgery. Anesthesiology 2015, 123, 515–523, doi: 10.1097/ALN.0000000000000765. Sun L.Y. Wijeysundera D.N. Tait G.A. Beattie W.S. Association of Intraoperative Hypotension with Acute Kidney Injury after Elective Noncardiac Surgery Anesthesiology 2015 123 515 523 10.1097/ALN.000000000000076526181335Open DOISearch in Google Scholar

39Vial H.J., Gorenflot A.: Chemotherapy against babesiosis. Vet Parasitol 2006, 138, 147–160, doi: 10.1016/j.vetpar.2006.01.048. Vial H.J. Gorenflot A. Chemotherapy against babesiosis Vet Parasitol 2006 138 147 160 10.1016/j.vetpar.2006.01.04816504402Open DOISearch in Google Scholar

40Walls J.J., Caturegli P., Bakken J.S., Asanovich K.M., Dumler J.S.: Improved sensitivity of PCR for diagnosis of human granulocytic ehrlichiosis using epank1 genes of Ehrlichia phagocytophila-group ehrlichiae. J Clin Microbiol 2000, 38, 354–356, doi: 10.1128/JCM.38.1.354-356.2000. Walls J.J. Caturegli P. Bakken J.S. Asanovich K.M. Dumler J.S. Improved sensitivity of PCR for diagnosis of human granulocytic ehrlichiosis using epank1 genes of Ehrlichia phagocytophila-group ehrlichiae J Clin Microbiol 2000 38 354 356 10.1128/JCM.38.1.354-356.20008872310618115Open DOISearch in Google Scholar

41Walsh M., Devereaux P.J., Garg A.X., Kurz A., Turan A., Rodseth R.N., Cywinski J., Thabane L., Sessler D.I.: Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension. Anesthesiology 2013, 119, 507–515, doi: 10.1097/ALN.0b013e3182a10e26. Walsh M. Devereaux P.J. Garg A.X. Kurz A. Turan A. Rodseth R.N. Cywinski J. Thabane L. Sessler D.I. Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension Anesthesiology 2013 119 507 515 10.1097/ALN.0b013e3182a10e2623835589Open DOISearch in Google Scholar

42Zygner W., Gójska-Zygner O., Bąska P., Długosz E.: Increased concentration of serum TNF alpha and its correlations with arterial blood pressure and indices of renal damage in dogs infected with Babesia canis. Parasitol Res 2014, 113, 1499–1503, doi: 10.1007/s00436-014-3792-1. Zygner W. Gójska-Zygner O. Bąska P. Długosz E. Increased concentration of serum TNF alpha and its correlations with arterial blood pressure and indices of renal damage in dogs infected with Babesia canis Parasitol Res 2014 113 1499 1503 10.1007/s00436-014-3792-1395188624553975Open DOISearch in Google Scholar

43Zygner W., Gójska-Zygner O., Bąska P., Długosz E.: Low T3 syndrome in canine babesiosis associated with increased serum IL-6 concentration and azotaemia. Vet Parasitol 2015, 211, 23–27, doi: 10.1016/j.vetpar.2015.04.023. Zygner W. Gójska-Zygner O. Bąska P. Długosz E. Low T3 syndrome in canine babesiosis associated with increased serum IL-6 concentration and azotaemia Vet Parasitol 2015 211 23 27 10.1016/j.vetpar.2015.04.02325976636Open DOISearch in Google Scholar

44Zygner W., Gójska-Zygner O., Wędrychowicz H.: Strong monovalent electrolyte imbalances in serum of dogs infected with Babesia canis. Ticks Tick Borne Dis 2012, 3, 107–113, doi: 10.1016/j.ttbdis.2012.02.002. Zygner W. Gójska-Zygner O. Wędrychowicz H. Strong monovalent electrolyte imbalances in serum of dogs infected with Babesia canis Ticks Tick Borne Dis 2012 3 107 113 10.1016/j.ttbdis.2012.02.00222463923Open DOISearch in Google Scholar