Collagen and Keratin as a Components of Hydrogels
Dorota Wieczorek
Łukasiewicz Research Network-Łódź Institute of Technology
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, Anna Słubik
Łukasiewicz Research Network-Łódź Institute of Technology
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, Iwona Masłowska-Lipowicz
Łukasiewicz Research Network-Łódź Institute of Technology
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, Dorota Gendaszewska
Łukasiewicz Research Network-Łódź Institute of Technology
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and Katarzyna Ławińska
Łukasiewicz Research Network-Łódź Institute of Technology
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Sep 28, 2022
About this article
Article Category: Research Article
Published Online: Sep 28, 2022
Page range: 61 - 69
DOI: https://doi.org/10.2478/ftee-2022-0024
Keywords
© 2022 Dorota Wieczorek, et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 3.0 Public License.
Fig. 1
![Examples of chemically (a–c) and physically (d–f) crosslinked hydrogels [7]](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6471db0b215d2f6c89db3264/j_ftee-2022-0024_fig_001.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20250911%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20250911T090925Z&X-Amz-Expires=3600&X-Amz-Signature=ffe35be0d910300efc5781548142eed10f1087d7802000b9a0dbc927c709fe60&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)
Fig. 2
![Structure of collagen (A) and keratin (B) [39, 51]](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6471db0b215d2f6c89db3264/j_ftee-2022-0024_fig_002.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20250911%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20250911T090925Z&X-Amz-Expires=3600&X-Amz-Signature=adc76cc8fb2c5b62908262075bec2ae84bad1627dae2f22268df51c2b4f9a6a3&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)
Fig. 3
![Fabrication scheme of collagen/PNIPAAm hydrogel [67]](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6471db0b215d2f6c89db3264/j_ftee-2022-0024_fig_003.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20250911%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20250911T090925Z&X-Amz-Expires=3600&X-Amz-Signature=02efb22ab9f2f0021d5cc2c426fa7697e9d1ad5216d1e88bfb7ad45e26b62e12&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)
Classification of hydrogel types based on the network nature
| Homopolymer | Poly(2-hydroxyethyl methacrylate) | [ |
| 2-Hydroxyethyl methacrylate (HEMA) | [ |
|
| Poly(vinyl alcohol) (PVA) | [ |
|
| Polyacrylamide (PAAm) | [ |
|
| Polyetylene glycol (PEG) | [ |
|
| Copolymer | Methacrylic acid (MAA) | [ |
| Carboxymethyl cellulose (CMC) | ||
| Polyvinylpyrrolidone (PVP) | ||
| Interpenetrating network | Poly(N-isopropylacrylamide) (PNIPAAm) | [ |
| Polyacrylamide-grafted-gum ghatti (PAAm-g-GG) and sodium alginate | [ |
|
| Polyacrylamide-grafted-tamarind seed polysaccharide (PAAm-g-TSP) | ||
| Poli(vinyl alcohol)/chitosan | [ |
|
| Hyaluronic acid–methylcellulose (HA-MC) | [ |
|
| Double-network hydrogels | Poly(2-acrylamido-2-methylpropanesulfonic acid) (PAMPS) as the first network and polyacrylamide as the second network | [ |
| Poly(2-acrylamido-2methylpropanesulfonic acid) as the first network and poly(N, N-dimethylacrylamide) (DMAA) or polyzwitterionic gels as the second network |
Sub-classification of responsive hydrogels [23]
| pH | Temperature | Antigens responsive |
| Glucose | Electricity light | Enzymes responsive |
| Oxidant | Pressure | Ligands responsive |
| Solvent composition | Sound and magnetic field | |
| Ions and specific molecular recognition events | ||