<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Smart hydrogels, or stimuli-responsive hydrogels, can and should play an important role as excellent drug carriers. These three-dimensional structure materials are composed of crosslinked hydrophilic polymer chains that are able to dramatically change their volume and other properties in response to environmental stimuli, such as pH, temperature and solvent changes. The main goal of individual research projects was the development of new hydrogels based on polypeptides. These hybrid materials are crosslinked hydrophilic polymers capable of absorbing large amounts of water, saline or physiological solutions. Superabsorbent hydrogels based on natural materials are non-toxic, biocompatible and biodegradable. Unfortunately, their mechanical properties in the swollen state are weak. In this article, we present a review of literature on the synthesis of smart hydrogels based on keratin or collagen with synthetic materials.</p>
</abstract>

Smart hydrogels, or stimuli-responsive hydrogels, can and should play an important role as excellent drug carriers. These three-dimensional structure materials are composed of crosslinked hydrophilic polymer chains that are able to dramatically change their volume and other properties in response to environmental stimuli, such as pH, temperature and solvent changes. The main goal of individual research projects was the development of new hydrogels based on polypeptides. These hybrid materials are crosslinked hydrophilic polymers capable of absorbing large amounts of water, saline or physiological solutions. Superabsorbent hydrogels based on natural materials are non-toxic, biocompatible and biodegradable. Unfortunately, their mechanical properties in the swollen state are weak. In this article, we present a review of literature on the synthesis of smart hydrogels based on keratin or collagen with synthetic materials.

Collagen and Keratin as a Components of Hydrogels

Fibres & Textiles in Eastern Europe

This work is licensed under the Creative Commons Attribution 3.0 Public License.

{"article-title":"Collagen and Keratin as a Components of Hydrogels"}

Smart hydrogels, or stimuli-responsive hydrogels, can and should play an important role as excellent drug carriers. These three-dimensional structure materials...

Type of hydrogel	Examples	References
Homopolymer	Poly(2-hydroxyethyl methacrylate)	[12]
	2-Hydroxyethyl methacrylate (HEMA)	[13]
	Poly(vinyl alcohol) (PVA)	[14]
	Polyacrylamide (PAAm)	[15]
	Polyetylene glycol (PEG)	[16]
Copolymer	Methacrylic acid (MAA)	[17]
	Carboxymethyl cellulose (CMC)
	Polyvinylpyrrolidone (PVP)
Interpenetrating network	Poly(N-isopropylacrylamide) (PNIPAAm)	[18]
	Polyacrylamide-grafted-gum ghatti (PAAm-g-GG) and sodium alginate	[19]
	Polyacrylamide-grafted-tamarind seed polysaccharide (PAAm-g-TSP)	[19]
	Poli(vinyl alcohol)/chitosan	[20]
	Hyaluronic acid–methylcellulose (HA-MC)	[21]
Double-network hydrogels	Poly(2-acrylamido-2-methylpropanesulfonic acid) (PAMPS) as the first network and polyacrylamide as the second network	[22]
Double-network hydrogels	Poly(2-acrylamido-2methylpropanesulfonic acid) as the first network and poly(N, N-dimethylacrylamide) (DMAA) or polyzwitterionic gels as the second network	[22]

Chemically responsive	Physically responsive	Biochemically responsive

pH	Temperature	Antigens responsive
Glucose	Electricity light	Enzymes responsive
Oxidant	Pressure	Ligands responsive
Solvent composition	Sound and magnetic field
Ions and specific molecular recognition events	Sound and magnetic field

Collagen and Keratin as a Components of Hydrogels

Article Category: Research Article

Publié en ligne: 28 sept. 2022

Pages: 61 - 69

DOI: https://doi.org/10.2478/ftee-2022-0024

Mots clés
biopolymers, collagen, keratin, smart hydrogel, applications

© 2022 Dorota Wieczorek, et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 3.0 Public License.

Fig. 1

Fig. 2

Fig. 3

Classification of hydrogel types based on the network nature

Sub-classification of responsive hydrogels [23]

Collagen and Keratin as a Components of Hydrogels

Article Category: Research Article

Publié en ligne: 28 sept. 2022

Pages: 61 - 69

DOI: https://doi.org/10.2478/ftee-2022-0024

Mots clésbiopolymers, collagen, keratin, smart hydrogel, applications

© 2022 Dorota Wieczorek, et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 3.0 Public License.

Fig. 1

Fig. 2

Fig. 3

Classification of hydrogel types based on the network nature

Sub-classification of responsive hydrogels [23]

Mots clés
biopolymers, collagen, keratin, smart hydrogel, applications