Medical Research During the COVID-19 Pandemic – Two Faces of the Same Coin

<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Aim:</bold> This study evaluated the correlations between metabolic parameters and reproductive health data in women with type 2 diabetes mellitus (T2DM).<bold>Material and methods:</bold> In this observational retrospective study, data from the medical records of 324 adult women with T2DM attending their regular diabetes check-ups were collected and analyzed (i.e., anthropometric parameters at first outpatient visit and yearly thereafter, first recorded HbA1c and all HbA1c for the entire follow-up duration, as well as obstetrical/gynecological information).<bold>Results:</bold> Age at the diagnosis of T2DM correlated positively with age at menarche (r = 0.21, [95% CI: 0.09, 0.31], p = 0.0002) and age at menopause (r = 0.18 [95% CI: 0.07, 0.29], p &lt;0.01). Age at menarche correlated negatively with mean weight (r = –0.21 [95% CI: –0.31, –0.10], p: 0.0002) and mean BMI (–0.22 [–0.32, –0.11], p &lt;0.0001) over the follow-up time. Patients with shorter time difference between age at menarche and age at onset of T2DM (≤45 years) had higher mean weight (83.8 ± 14.5 kg vs. 78.4 ± 16.0 kg, p = 0.0001), BMI (33.2 ± 5.6 kg/m2 vs. 31.8 ± 5.7 kg/m2, p &lt;0.05), and HbA1c over time (6.9 ± 0.8% vs. 6.6 ± 0.9%, p &lt;0.0001). Women with T2DM with earlier menarche (&lt;12 years old), with irregular menses during their reproductive life, and ≥3 pregnancies had higher overall BMI, but mean HbA1c were not significantly different. However, women diagnosed with T2DM before menopause had a higher mean HbA1c over time (7.1 ± 0.8% vs. 6.7 ± 0.9%, p &lt;0.01).<bold>Conclusion:</bold> The BMI correlated with several indicators of reproductive health (earlier menarche, irregular menses, and higher number of pregnancies), while earlier onset of T2DM influenced metabolic control in women with T2DM.</abstract>

“George Emil Palade” University of Medicine, Pharmacy, Science, and Technology

Reproductive Health and Metabolic Parameters in Women with Type 2 Diabetes

<abstract xmlns="http://www.w3.org/1999/xhtml">The aim of this study was to estimate the prevalence of self-reported work-related and occupational hand eczema, as well as associated risk factors in hospitals and out-patient clinics in Romania. A standardized questionnaire was addressed to health professionals from different medical fields. Out of 245 healthcare providers who completed the survey, 235 were women (95.9%), and 243 were working more than 8 hours/day in hospitals (99.18%). Hand eczema was self-reported and documented in almost one third of the nurses (33.49%), the most frequently involved trigger factor being powdered latex gloves. A total of 207 (84.48%) individuals denied any present or past allergic diseases. Only one nurse declared that severe hand eczema was the cause of losing her job at the hospital. Exposure assessment is essential for the diagnosis of work-related or occupational skin diseases.</abstract>

“Grigore T. Popa” University of Medicine and Pharmacy

“Carol Davila” University of Medicine and Pharmacy

“George Emil Palade” University of Medicine, Pharmacy, Science and Technology

The Utility of a Questionnaire Proposal as an Analytic Diagnostic Tool in Healthcare Providers Occupational Hand Eczema

<abstract xmlns="http://www.w3.org/1999/xhtml">Hypertension is one of the main cardiovascular risk factors, and it remains an important health problem, demonstrating an increasing incidence despite new treatment methods. Numerous risk factors that can lead to the development of difficult-to-treat or resistant hypertension have been described in the literature in recent years. In this type of hypertension, an important role is played by the sympathetic nervous system. Especially in these cases, with a sympathetic overactivation, renal denervation has proven its efficacy and safety in lowering blood pressure. In this brief clinical update, we present the results of the main studies regarding the efficacy and safety of the renal denervation technique used in the treatment of resistant hypertension.</abstract>

Clinic of Cardiology, “George Emil Palade” University of Medicine and Pharmacy, Science and Technology

“George Emil Palade” University of Medicine and Pharmacy, Science and Technology

Renal Denervation – a Modern Option for Treating Resistant Hypertension

<abstract xmlns="http://www.w3.org/1999/xhtml">Acute fatty liver of pregnancy (AFLP) is a rare but life-threatening condition that develops in the third trimester of pregnancy. AFLP shares similar clinical features with other more common pregnancy-associated conditions. However, early correct diagnosis is important for maternal and fetal survival. Once the diagnosis has been established, immediate delivery and maternal intensive support should be undertaken. Both parents and the infant should be tested for deficiencies of the mitochondrial fatty acid oxidation, especially for long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency, as many cases of AFLP are related to disruption of this physiological enzymatic pathway.</abstract>

Acute Fatty Liver of Pregnancy

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Journal of Interdisciplinary Medicine

 The Journal of Interdisciplinary Medicine aims to publish top quality papers related to any fields of medicine that present an interdisciplinary dimension.  The journal will mainly focus on recent advances in the field of diagnosis and treatment of the most common situations encountered in the clinical or research practice. Interdisciplinary approaches will be extremely welcomed, presenting new advances in the approach of different pathologies from the perspective of various clinical fields.  The Journal of Interdisciplinary Medicine will publish high-quality basic and clinical research related to interdisciplinary medical fields, in a common approach that will integrate the clinical studies with the pre-clinical work dedicated to discovery of new mechanisms involved in the development and progression of a large spectrum of diseases.  The journal will try to provide the entire medical community with the perspective of the regional specifics in Central and Eastern European countries. The journal will primarily focus on publishing original research papers, but also other types of materials (such as review articles, case reports, state of the art papers, comments to editor, etc) will be extremely welcomed.  Rejection Rate:   30%   Archiving  Sciendo archives the contents of this journal in Portico - digital long-term preservation service of scholarly books, journals and collections.  Plagiarism Policy  The editorial board is participating in a growing community of Similarity Check System's users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process. 