Immunotherapy with Interleukin-2: A Study Based on Mathematical Modeling
| 06 paź 2008
International Journal of Applied Mathematics and Computer Science
Selected Problems of Computer Science and Control (special issue), Krzysztof Gałkowski, Eric Rogers and Jan Willems (Eds.)
O artykule
Data publikacji: 06 paź 2008
Zakres stron: 389 - 398
DOI: https://doi.org/10.2478/v10006-008-0035-6
Słowa kluczowe
This content is open access.
The role of interleukin-2 (IL-2) in tumor dynamics is illustrated through mathematical modeling, using delay differential equations with a discrete time delay (a modified version of the Kirshner-Panetta model). Theoretical analysis gives an expression for the discrete time delay and the length of the time delay to preserve stability. Numerical analysis shows that interleukin-2 alone can cause the tumor cell population to regress.