<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Acromegaly is associated with cardiovascular disease, the principal cause of increased mortality. Direct cardiac effects of GH/IGF-1 are cardiomyocyte growth and cardiac contractility, cardiac remoddeling. Other important risk factors in acromegaly are hypertension, valvular diseases, arrhytmias. Older patients with long-term uncontrolled disease may develop congestive heart failure as end-stage of acromegalic cardiomyopathy. Early treatment of acromegaly is essential for evolution and prognosis of cardiovascular complications.</p>
</abstract>

Acromegaly is associated with cardiovascular disease, the principal cause of increased mortality. Direct cardiac effects of GH/IGF-1 are cardiomyocyte growth and cardiac contractility, cardiac remoddeling. Other important risk factors in acromegaly are hypertension, valvular diseases, arrhytmias. Older patients with long-term uncontrolled disease may develop congestive heart failure as end-stage of acromegalic cardiomyopathy. Early treatment of acromegaly is essential for evolution and prognosis of cardiovascular complications.

Cardiovascular Risk in Acromegaly

“Carol Davila” University of Medicine and Pharmacy

Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Cardiovascular Risk in Acromegaly"}

Acromegaly is associated with cardiovascular disease, the principal cause of increased mortality. Direct cardiac effects of GH/IGF-1 are cardiomyocyte growth...

Cardiovascular Risk in Acromegaly

Data publikacji: 15 kwi 2023

Zakres stron: 43 - 55

DOI: https://doi.org/10.2478/inmed-2023-0237

Słowa kluczowe
cardiomyocyte growth, cardiomyopathy, hypertension, valvular diseases

© 2023 Mariana Dobrescu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Cardiovascular Risk in Acromegaly

Data publikacji: 15 kwi 2023

Zakres stron: 43 - 55

DOI: https://doi.org/10.2478/inmed-2023-0237

Słowa kluczowecardiomyocyte growth, cardiomyopathy, hypertension, valvular diseases

© 2023 Mariana Dobrescu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Słowa kluczowe
cardiomyocyte growth, cardiomyopathy, hypertension, valvular diseases