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Deep Cross-Organism Generalization of the Physiological Effects of Spaceflight from Mammalian Model Organisms to Humans

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02 lip 2025

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Adamopoulos K, Koutsouris D, Zaravinos A, Lambrou GI (2021) Gravitational influence on human living systems and the evolution of species on Earth. Molecules 26 AdamopoulosK KoutsourisD ZaravinosA LambrouGI 2021 Gravitational influence on human living systems and the evolution of species on Earth Molecules 26 Search in Google Scholar

Afshinnekoo E, et al. (2020) Fundamental biological features of spaceflight: Advancing the field to enable deep-space exploration. Cell 183:1162–84 AfshinnekooE 2020 Fundamental biological features of spaceflight: Advancing the field to enable deep-space exploration Cell 183 1162 84 Search in Google Scholar

Allen DL, et al. (2009) Effects of spaceflight on murine skeletal muscle gene expression. Journal of Applied Physiology 106:582–95 AllenDL 2009 Effects of spaceflight on murine skeletal muscle gene expression Journal of Applied Physiology 106 582 95 Search in Google Scholar

Bauer-Mehren A, Rautschka M, Sanz F, Furlong LI (2010) DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene–disease networks. Bioinformatics 26:2924–26 Bauer-MehrenA RautschkaM SanzF FurlongLI 2010 DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene–disease networks Bioinformatics 26 2924 26 Search in Google Scholar

Becker KG, Barnes KC, Bright TJ, Wang SA (2004) The genetic association database. Nature Genetics 36:431–32 BeckerKG BarnesKC BrightTJ WangSA 2004 The genetic association database Nature Genetics 36 431 32 Search in Google Scholar

Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society. Series B (Methodological) 57:289–300 BenjaminiY HochbergY 1995 Controlling the false discovery rate: a practical and powerful approach to multiple testing Journal of the Royal Statistical Society. Series B (Methodological) 57 289 300 Search in Google Scholar

Berrios DC, Galazka J, Grigorev K, Gebre S, Costes SV (2021) NASA GeneLab: interfaces for the exploration of space omics data. Nucleic Acids Research 49:D1515–D1522 BerriosDC GalazkaJ GrigorevK GebreS CostesSV 2021 NASA GeneLab: interfaces for the exploration of space omics data Nucleic Acids Research 49 D1515 D1522 Search in Google Scholar

Blottner D, et al. (2022) Reciprocal Homer1a and Homer2 isoform expression is a key mechanism for muscle soleus atrophy in spaceflown mice. International Journal of Molecular Sciences 23 BlottnerD 2022 Reciprocal Homer1a and Homer2 isoform expression is a key mechanism for muscle soleus atrophy in spaceflown mice International Journal of Molecular Sciences 23 Search in Google Scholar

Brungs S, et al. (2016) Facilities for simulation of microgravity in the ESA ground-based facility programme. Microgravity Science and Technology 28:191–203 BrungsS 2016 Facilities for simulation of microgravity in the ESA ground-based facility programme Microgravity Science and Technology 28 191 203 Search in Google Scholar

Cahill T, et al. (2021) Mammalian and invertebrate models as complementary tools for gaining mechanistic insight on muscle responses to spaceflight. International Journal of Molecular Sciences 22 CahillT 2021 Mammalian and invertebrate models as complementary tools for gaining mechanistic insight on muscle responses to spaceflight International Journal of Molecular Sciences 22 Search in Google Scholar

Carvalho BS, Irizarry RA (2010) A framework for oligonucleotide microarray preprocessing. Bioinformatics 26:2363–7 CarvalhoBS IrizarryRA 2010 A framework for oligonucleotide microarray preprocessing Bioinformatics 26 2363 7 Search in Google Scholar

Chakraborty N, et al. (2021) Gene-metabolite networks associated with impediment of bone fracture repair in spaceflight. Computational and Structural Biotechnology Journal 19:3507–20 ChakrabortyN 2021 Gene-metabolite networks associated with impediment of bone fracture repair in spaceflight Computational and Structural Biotechnology Journal 19 3507 20 Search in Google Scholar

Chawla N, Bowyer K, Hall LO, Kegelmeyer WP (2002) SMOTE: synthetic minority over-sampling technique. ArXiv abs/1106.1813 ChawlaN BowyerK HallLO KegelmeyerWP 2002 SMOTE: synthetic minority over-sampling technique ArXiv abs/1106.1813 Search in Google Scholar

Developers T (2024) TensorFlow. Preprint at https://doi.org/10.5281/zenodo.12726004 DevelopersT 2024 TensorFlow Preprint at https://doi.org/10.5281/zenodo.12726004 Search in Google Scholar

Gambara G, et al. (2017) Gene expression profiling in slow-type calf soleus muscle of 30 days space-flown mice. PLoS One 12:e0169314 GambaraG 2017 Gene expression profiling in slow-type calf soleus muscle of 30 days space-flown mice PLoS One 12 e0169314 Search in Google Scholar

Gautier L, Cope L, Bolstad BM, Irizarry RA (2004) affy—analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20:307–15 GautierL CopeL BolstadBM IrizarryRA 2004 affy—analysis of Affymetrix GeneChip data at the probe level Bioinformatics 20 307 15 Search in Google Scholar

Harris CR, et al. (2020) Array programming with NumPy. Nature 585:357–62 HarrisCR 2020 Array programming with NumPy Nature 585 357 62 Search in Google Scholar

Huang DW, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protocols 4:44–57 HuangDW ShermanBT LempickiRA 2009 Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nature Protocols 4 44 57 Search in Google Scholar

Hunter JD (2007) Matplotlib: a 2D graphics environment. Computing in Science and Engineering 9:90–95 HunterJD 2007 Matplotlib: a 2D graphics environment Computing in Science and Engineering 9 90 95 Search in Google Scholar

Kiss JZ, Wolverton C, Wyatt SE, Hasenstein KH, van Loon JWA (2019) Comparison of microgravity analogs to spaceflight in studies of plant growth and development. Frontiers in Plant Science 10 KissJZ WolvertonC WyattSE HasensteinKH van LoonJWA 2019 Comparison of microgravity analogs to spaceflight in studies of plant growth and development Frontiers in Plant Science 10 Search in Google Scholar

Liphardt AM, Fernandez-Gonzalo R, Albracht K, Rittweger J, Vico L (2023) Musculoskeletal research in human space flight – unmet needs for the success of crewed deep space exploration. Nature Partner Journals Microgravity 9:9 LiphardtAM Fernandez-GonzaloR AlbrachtK RittwegerJ VicoL 2023 Musculoskeletal research in human space flight – unmet needs for the success of crewed deep space exploration Nature Partner Journals Microgravity 9 9 Search in Google Scholar

Man J, Graham T, Squires-Donelly G, Laslett AL (2022) The effects of microgravity on bone structure and function. Nature Partner Journals Microgravity 8:9 ManJ GrahamT Squires-DonellyG LaslettAL 2022 The effects of microgravity on bone structure and function Nature Partner Journals Microgravity 8 9 Search in Google Scholar

Mason CE, et al. (2024) A second space age spanning omics, platforms, and medicine across orbits. Nature MasonCE 2024 A second space age spanning omics, platforms, and medicine across orbits Nature Search in Google Scholar

Morey-Holton ER (2003) 9 - The impact of gravity on life. In Evolution on Planet Earth, LJ Rothschild, AM Lister (eds), pp 143–59. London: Academic Press. Morey-HoltonER 2003 9 - The impact of gravity on life In Evolution on Planet Earth RothschildLJ ListerAM (eds), 143 59 London Academic Press Search in Google Scholar

Morey-Holton ER, Globus RK (2002) Hindlimb unloading rodent model: technical aspects. Journal of Applied Physiology 92:1367–77 Morey-HoltonER GlobusRK 2002 Hindlimb unloading rodent model: technical aspects Journal of Applied Physiology 92 1367 77 Search in Google Scholar

Moyer EL, et al. (2016) Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days). Nature Partner Journals Microgravity 2:16002 MoyerEL 2016 Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days) Nature Partner Journals Microgravity 2 16002 Search in Google Scholar

Overbey EG, et al. (2024) The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature OverbeyEG 2024 The Space Omics and Medical Atlas (SOMA) and international astronaut biobank Nature Search in Google Scholar

Pedregosa F, et al. (2011) Scikit-learn: machine learning in Python. Journal of Machine Learning Research 12:2825–30 PedregosaF 2011 Scikit-learn: machine learning in Python Journal of Machine Learning Research 12 2825 30 Search in Google Scholar

Ramachandran R, Bugbee K, Murphy K (2021) From open data to open science. Earth and Space Science 8:e2020EA001562 RamachandranR BugbeeK MurphyK 2021 From open data to open science Earth and Space Science 8 e2020EA001562 Search in Google Scholar

Ray S, et al. (2019) GeneLab: omics database for spaceflight experiments. Bioinformatics 35:1753–1759 RayS 2019 GeneLab: omics database for spaceflight experiments Bioinformatics 35 1753 1759 Search in Google Scholar

Reynolds RJ, et al. (2022) Validating causal diagrams of human health risks for spaceflight: An example using bone data from rodents. Biomedicines 10 ReynoldsRJ 2022 Validating causal diagrams of human health risks for spaceflight: An example using bone data from rodents Biomedicines 10 Search in Google Scholar

Ritchie ME, et al. (2015) Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Research 43:e47 RitchieME 2015 Limma powers differential expression analyses for RNA-sequencing and microarray studies Nucleic Acids Research 43 e47 Search in Google Scholar

Ronca AE, Lowe MG (2022) Rodents as a model for research in space. In Handbook of Space Pharmaceuticals, YV Pathak, M Araújo dos Santos, L Zea (eds), pp 679–700. Cham: Springer International Publishing. RoncaAE LoweMG 2022 Rodents as a model for research in space In Handbook of Space Pharmaceuticals PathakYV Araújo dos SantosM ZeaL (eds), 679 700 Cham Springer International Publishing Search in Google Scholar

Rutter LA, et al. (2024) Astronaut omics and the impact of space on the human body at scale. Nature Communications 15:4952 RutterLA 2024 Astronaut omics and the impact of space on the human body at scale Nature Communications 15 4952 Search in Google Scholar

Sherman BT, et al. (2022) DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update). Nucleic Acids Research 50:W216–21 ShermanBT 2022 DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update) Nucleic Acids Research 50 W216 21 Search in Google Scholar

Van Rossum G, Drake FL (2009) Python 3 Reference Manual. Scotts Valley, CA: CreateSpace Van RossumG DrakeFL 2009 Python 3 Reference Manual Scotts Valley, CA CreateSpace Search in Google Scholar

Waskom M (2021) seaborn: statistical data visualization. Journal of Open Source Software 6:3021 WaskomM 2021 seaborn: statistical data visualization Journal of Open Source Software 6 3021 Search in Google Scholar

Język:
Angielski
Częstotliwość wydawania:
2 razy w roku
Dziedziny czasopisma:
Nauki biologiczne, Nauki biologiczne, inne, Nauka o materiałach, Nauka o materiałach, inne, Fizyka, Fizyka, inne