This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Adamopoulos K, Koutsouris D, Zaravinos A, Lambrou GI (2021) Gravitational influence on human living systems and the evolution of species on Earth. Molecules 26AdamopoulosKKoutsourisDZaravinosALambrouGI2021Gravitational influence on human living systems and the evolution of species on EarthMolecules26Search in Google Scholar
Afshinnekoo E, et al. (2020) Fundamental biological features of spaceflight: Advancing the field to enable deep-space exploration. Cell 183:1162–84AfshinnekooE2020Fundamental biological features of spaceflight: Advancing the field to enable deep-space explorationCell183116284Search in Google Scholar
Allen DL, et al. (2009) Effects of spaceflight on murine skeletal muscle gene expression. Journal of Applied Physiology 106:582–95AllenDL2009Effects of spaceflight on murine skeletal muscle gene expressionJournal of Applied Physiology10658295Search in Google Scholar
Bauer-Mehren A, Rautschka M, Sanz F, Furlong LI (2010) DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene–disease networks. Bioinformatics 26:2924–26Bauer-MehrenARautschkaMSanzFFurlongLI2010DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene–disease networksBioinformatics26292426Search in Google Scholar
Becker KG, Barnes KC, Bright TJ, Wang SA (2004) The genetic association database. Nature Genetics 36:431–32BeckerKGBarnesKCBrightTJWangSA2004The genetic association databaseNature Genetics3643132Search in Google Scholar
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society. Series B (Methodological) 57:289–300BenjaminiYHochbergY1995Controlling the false discovery rate: a practical and powerful approach to multiple testingJournal of the Royal Statistical Society. Series B (Methodological)57289300Search in Google Scholar
Berrios DC, Galazka J, Grigorev K, Gebre S, Costes SV (2021) NASA GeneLab: interfaces for the exploration of space omics data. Nucleic Acids Research 49:D1515–D1522BerriosDCGalazkaJGrigorevKGebreSCostesSV2021NASA GeneLab: interfaces for the exploration of space omics dataNucleic Acids Research49D1515D1522Search in Google Scholar
Blottner D, et al. (2022) Reciprocal Homer1a and Homer2 isoform expression is a key mechanism for muscle soleus atrophy in spaceflown mice. International Journal of Molecular Sciences 23BlottnerD2022Reciprocal Homer1a and Homer2 isoform expression is a key mechanism for muscle soleus atrophy in spaceflown miceInternational Journal of Molecular Sciences23Search in Google Scholar
Brungs S, et al. (2016) Facilities for simulation of microgravity in the ESA ground-based facility programme. Microgravity Science and Technology 28:191–203BrungsS2016Facilities for simulation of microgravity in the ESA ground-based facility programmeMicrogravity Science and Technology28191203Search in Google Scholar
Cahill T, et al. (2021) Mammalian and invertebrate models as complementary tools for gaining mechanistic insight on muscle responses to spaceflight. International Journal of Molecular Sciences 22CahillT2021Mammalian and invertebrate models as complementary tools for gaining mechanistic insight on muscle responses to spaceflightInternational Journal of Molecular Sciences22Search in Google Scholar
Carvalho BS, Irizarry RA (2010) A framework for oligonucleotide microarray preprocessing. Bioinformatics 26:2363–7CarvalhoBSIrizarryRA2010A framework for oligonucleotide microarray preprocessingBioinformatics2623637Search in Google Scholar
Chakraborty N, et al. (2021) Gene-metabolite networks associated with impediment of bone fracture repair in spaceflight. Computational and Structural Biotechnology Journal 19:3507–20ChakrabortyN2021Gene-metabolite networks associated with impediment of bone fracture repair in spaceflightComputational and Structural Biotechnology Journal19350720Search in Google Scholar
Chawla N, Bowyer K, Hall LO, Kegelmeyer WP (2002) SMOTE: synthetic minority over-sampling technique. ArXiv abs/1106.1813ChawlaNBowyerKHallLOKegelmeyerWP2002SMOTE: synthetic minority over-sampling techniqueArXiv abs/1106.1813Search in Google Scholar
Developers T (2024) TensorFlow. Preprint at https://doi.org/10.5281/zenodo.12726004DevelopersT2024TensorFlowPreprint at https://doi.org/10.5281/zenodo.12726004Search in Google Scholar
Gambara G, et al. (2017) Gene expression profiling in slow-type calf soleus muscle of 30 days space-flown mice. PLoS One 12:e0169314GambaraG2017Gene expression profiling in slow-type calf soleus muscle of 30 days space-flown micePLoS One12e0169314Search in Google Scholar
Gautier L, Cope L, Bolstad BM, Irizarry RA (2004) affy—analysis of Affymetrix GeneChip data at the probe level. Bioinformatics 20:307–15GautierLCopeLBolstadBMIrizarryRA2004affy—analysis of Affymetrix GeneChip data at the probe levelBioinformatics2030715Search in Google Scholar
Harris CR, et al. (2020) Array programming with NumPy. Nature 585:357–62HarrisCR2020Array programming with NumPyNature58535762Search in Google Scholar
Huang DW, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protocols 4:44–57HuangDWShermanBTLempickiRA2009Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesNature Protocols44457Search in Google Scholar
Hunter JD (2007) Matplotlib: a 2D graphics environment. Computing in Science and Engineering 9:90–95HunterJD2007Matplotlib: a 2D graphics environmentComputing in Science and Engineering99095Search in Google Scholar
Kiss JZ, Wolverton C, Wyatt SE, Hasenstein KH, van Loon JWA (2019) Comparison of microgravity analogs to spaceflight in studies of plant growth and development. Frontiers in Plant Science 10KissJZWolvertonCWyattSEHasensteinKHvan LoonJWA2019Comparison of microgravity analogs to spaceflight in studies of plant growth and developmentFrontiers in Plant Science10Search in Google Scholar
Liphardt AM, Fernandez-Gonzalo R, Albracht K, Rittweger J, Vico L (2023) Musculoskeletal research in human space flight – unmet needs for the success of crewed deep space exploration. Nature Partner Journals Microgravity 9:9LiphardtAMFernandez-GonzaloRAlbrachtKRittwegerJVicoL2023Musculoskeletal research in human space flight – unmet needs for the success of crewed deep space explorationNature Partner Journals Microgravity99Search in Google Scholar
Man J, Graham T, Squires-Donelly G, Laslett AL (2022) The effects of microgravity on bone structure and function. Nature Partner Journals Microgravity 8:9ManJGrahamTSquires-DonellyGLaslettAL2022The effects of microgravity on bone structure and functionNature Partner Journals Microgravity89Search in Google Scholar
Mason CE, et al. (2024) A second space age spanning omics, platforms, and medicine across orbits. NatureMasonCE2024A second space age spanning omics, platforms, and medicine across orbitsNatureSearch in Google Scholar
Morey-Holton ER (2003) 9 - The impact of gravity on life. In Evolution on Planet Earth, LJ Rothschild, AM Lister (eds), pp 143–59. London: Academic Press.Morey-HoltonER20039 - The impact of gravity on lifeInEvolution on Planet EarthRothschildLJListerAM(eds),14359LondonAcademic PressSearch in Google Scholar
Morey-Holton ER, Globus RK (2002) Hindlimb unloading rodent model: technical aspects. Journal of Applied Physiology 92:1367–77Morey-HoltonERGlobusRK2002Hindlimb unloading rodent model: technical aspectsJournal of Applied Physiology92136777Search in Google Scholar
Moyer EL, et al. (2016) Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days). Nature Partner Journals Microgravity 2:16002MoyerEL2016Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days)Nature Partner Journals Microgravity216002Search in Google Scholar
Overbey EG, et al. (2024) The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. NatureOverbeyEG2024The Space Omics and Medical Atlas (SOMA) and international astronaut biobankNatureSearch in Google Scholar
Pedregosa F, et al. (2011) Scikit-learn: machine learning in Python. Journal of Machine Learning Research 12:2825–30PedregosaF2011Scikit-learn: machine learning in PythonJournal of Machine Learning Research12282530Search in Google Scholar
Ramachandran R, Bugbee K, Murphy K (2021) From open data to open science. Earth and Space Science 8:e2020EA001562RamachandranRBugbeeKMurphyK2021From open data to open scienceEarth and Space Science8e2020EA001562Search in Google Scholar
Ray S, et al. (2019) GeneLab: omics database for spaceflight experiments. Bioinformatics 35:1753–1759RayS2019GeneLab: omics database for spaceflight experimentsBioinformatics3517531759Search in Google Scholar
Reynolds RJ, et al. (2022) Validating causal diagrams of human health risks for spaceflight: An example using bone data from rodents. Biomedicines 10ReynoldsRJ2022Validating causal diagrams of human health risks for spaceflight: An example using bone data from rodentsBiomedicines10Search in Google Scholar
Ritchie ME, et al. (2015) Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Research 43:e47RitchieME2015Limma powers differential expression analyses for RNA-sequencing and microarray studiesNucleic Acids Research43e47Search in Google Scholar
Ronca AE, Lowe MG (2022) Rodents as a model for research in space. In Handbook of Space Pharmaceuticals, YV Pathak, M Araújo dos Santos, L Zea (eds), pp 679–700. Cham: Springer International Publishing.RoncaAELoweMG2022Rodents as a model for research in spaceInHandbook of Space PharmaceuticalsPathakYVAraújo dos SantosMZeaL(eds),679700ChamSpringer International PublishingSearch in Google Scholar
Rutter LA, et al. (2024) Astronaut omics and the impact of space on the human body at scale. Nature Communications 15:4952RutterLA2024Astronaut omics and the impact of space on the human body at scaleNature Communications154952Search in Google Scholar
Sherman BT, et al. (2022) DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update). Nucleic Acids Research 50:W216–21ShermanBT2022DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)Nucleic Acids Research50W21621Search in Google Scholar
Van Rossum G, Drake FL (2009) Python 3 Reference Manual. Scotts Valley, CA: CreateSpaceVan RossumGDrakeFL2009Python 3 Reference ManualScotts Valley, CACreateSpaceSearch in Google Scholar
Waskom M (2021) seaborn: statistical data visualization. Journal of Open Source Software 6:3021WaskomM2021seaborn: statistical data visualizationJournal of Open Source Software63021Search in Google Scholar