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Depression in adolescents exposed to war trauma Risk factors for development of depression in adolescents exposed to war trauma: does PTSD matter?


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Figure 1

CONSORT diagram. TBI – traumatic brain injury; OCD – obsessive-compulsive disorder; GAD – generalized anxiety disorder; CD – conduct disorder; ADHD – attention deficit/hyperactivity disorder; PTSD – posttraumatic stress disorder.
CONSORT diagram. TBI – traumatic brain injury; OCD – obsessive-compulsive disorder; GAD – generalized anxiety disorder; CD – conduct disorder; ADHD – attention deficit/hyperactivity disorder; PTSD – posttraumatic stress disorder.

Figure 2

Changes in severity of PTSD on CAPS-CA in adolescents enrolled in the year long studyNote. PTSD –posttraumatic stress disorder; CAPS-CA - Clinician-administered ptsd scale child/adolescent version
Changes in severity of PTSD on CAPS-CA in adolescents enrolled in the year long studyNote. PTSD –posttraumatic stress disorder; CAPS-CA - Clinician-administered ptsd scale child/adolescent version

Figure 3

Changes in depression severity on CDRS-R in adolescents enrolled in the year long studyNote. CDRS-R - Children's depression rating scale-revised
Changes in depression severity on CDRS-R in adolescents enrolled in the year long studyNote. CDRS-R - Children's depression rating scale-revised

Description of mental health care provided in the community to adolescents with PTSD involved in the study

Variable%
Received TF-CBT32,9%
Received Fluoxetine20,25%
Being hospitalized6,3%
Received regular care46,8%

Risk and protective factors for development of depression in adolescents with war-related PTSD

Risk/Protective factorFinal model
BSEWOR95% CI
Female gender.382.744.2631.46.34–6.3
Secondary traumaa1.895.7186.9636.65**1.62–27.1
School non-attendinga2.485.70812.32912.0***2.99–48.0
TF-CBT− 2.8561.0347.625.058**.008–.437
Fluoxetine.714.859.6912.04.37–10.98

Socio-demographic data and characteristics of traumatic exposure of adolescents enrolled in the study

VariableM (SD)/ Median (IQR)/ n (%)P value
PTSDNon-PTSD
Age (years)15.87 (0.77)15.86 (0.76)> .05
Female gender38 (48.1%)29 (41.4%)> .05
Time since trauma, months8.0 (6.0–9.0)8.0 (6.0–9.0)> .05
Number of traumatic events exposed3.0 (2.0–4.0)2.0 (1.0–3.0)> .05
Characteristics of war-exposure:
- bombardments27 (34.1%)20 (28.5%)> .05
- rifle fire30 (37.9%)24 (30.3%)> .05
- injured7 (8.8%)5 (7.1%)> .05
- parents injured17 (21.5%)12 (17.1%)> .05
- saw dead bodies48 (60.7%)36 (51.4%)> .05
- living in shelters52 (65.8%)45 (64.2%)> .05
- house damaged30 (37.9%)25 (35.7%)> .05

Characteristics of post-displacement traumatic exposure of adolescents at study endpoint (T2)

VariableM (SD)/ Median (IQR)/ n (%)P value
PTSDNon-PTSD
Number of post-displacement traumatic events exposed0.0 (0.0–1.0)0.0 (0.0–1.0)> .05
Characteristics of post-displacement:
- bullying15 (18.9%)10 (14.2%)> .05
- loss of financial/social status18 (22.7%)13 (18.5%)> .05
- parents divorced7 (8.8%)4 (5.7%)> .05
- parent lost job11 (13.9%)8 (11.4%)> .05
- grandparent died1 (1.2%)1 (1.4%)> .05

Results of logistic regression predicting onset of depression in children exposed to war-related traumatic events

Risk factorFinal model
BSEWOR95% CI
Female gender1.049.5014.3782.85*1.06–7.62
PTSD1.466.5477.1824.33**1.48–12.64
Secondary traumaa.548.4991.2081.73.65–4.6
School non-attendinga2.334.51520.55710.3***3.76–28.2