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Figure 1:
Chest computed tomography (CT) scan: Speculated soft tissue mass seen on the left main bronchus, measuring about 6.1 × 5.2 cm (measured lesion) and associated with subcarinal ln and minimal pleural effusion.
Microscopic examination. (A) (Hematoxylin and eosin; ×20). Photomicrograph that shows infiltration of thyroid gland tissue by malignant tumoral proliferation formed of malignant acini lined by multiple layers of malignant epithelial cells with moderate degree atypia and abundant pale eosinophilic to clear cytoplasm (B) (Napsin A immunohistochemistry; ×20), diffuse positive with negative reaction of the surrounding thyroid tissue. (C) (Thyroglobulin immunohistochemistry; ×10), malignant acini that show negative reaction for thyroglobulin with the positive reaction of the surrounding thyroid tissue (internal control). (D) (×10), Malignant deposits of the cervical lymph node by the same tumor tissue with a small rim of lymphoid tissue on the periphery. (E) (Napsin A immunohistochemistry; ×20), diffuse positive reaction. (F) (Thyroglobulin immunohistochemistry; ×20), negative reaction.