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Forum of Clinical Oncology
AHEAD OF PRINT
Accès libre
Lung cancer with thyroid and colon metastases: a report of two cases
Maha Saif
Maha Saif
,
Manar Hamed
Manar Hamed
,
Wagdi Elkashef
Wagdi Elkashef
,
Dina Abdallah Ibrahim
Dina Abdallah Ibrahim
,
Heba Sheta
Heba Sheta
,
Reem Khaled
Reem Khaled
,
Mohamed Ezzat
Mohamed Ezzat
,
Omar Hamdy
Omar Hamdy
et
Shadi Awny
Shadi Awny
| 27 juin 2024
Forum of Clinical Oncology
AHEAD OF PRINT
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Article Category:
Case report
Publié en ligne:
27 juin 2024
Pages:
-
Reçu:
01 déc. 2023
Accepté:
04 mai 2024
DOI:
https://doi.org/10.2478/fco-2023-0023
Mots clés
Lung cancer
,
metastasis
,
thyroid cancer
,
intestinal obstruction
,
case report
© 2024 Maha Saif et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Figure 1:
Chest computed tomography (CT) scan: Speculated soft tissue mass seen on the left main bronchus, measuring about 6.1 × 5.2 cm (measured lesion) and associated with subcarinal ln and minimal pleural effusion.
Figure 2:
Microscopic examination. (A) (Hematoxylin and eosin; ×40). Moderately differentiated adenocarcinoma infiltrates the colonic wall. (B) (CK7 immunohistochemistry; ×40), diffuse positive. (C) (TTF-1 immunohistochemistry; ×40), diffuse positive. (D) (Napsin A immunohistochemistry; ×40), diffuse positive. (E) (CK20 immunohistochemistry; ×40), negative reaction. (F) (CDX2 immunohistochemistry; ×40), negative reaction.
Figure 3:
Microscopic examination. (A) (Hematoxylin and eosin; ×20). Photomicrograph that shows infiltration of thyroid gland tissue by malignant tumoral proliferation formed of malignant acini lined by multiple layers of malignant epithelial cells with moderate degree atypia and abundant pale eosinophilic to clear cytoplasm (B) (Napsin A immunohistochemistry; ×20), diffuse positive with negative reaction of the surrounding thyroid tissue. (C) (Thyroglobulin immunohistochemistry; ×10), malignant acini that show negative reaction for thyroglobulin with the positive reaction of the surrounding thyroid tissue (internal control). (D) (×10), Malignant deposits of the cervical lymph node by the same tumor tissue with a small rim of lymphoid tissue on the periphery. (E) (Napsin A immunohistochemistry; ×20), diffuse positive reaction. (F) (Thyroglobulin immunohistochemistry; ×20), negative reaction.