[Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, Landreth G, Lue L, Mrak R, Mackenzie IR, McGeer PL, O’Banion MK, Pachter J, Pasinetti G, Plata-Salaman C, Rogers J, Rydel R, Shen Y, Streit W, Strohmeyer R, Tooyoma I, Van Muiswinkel FL, Veerhuis R, Walker D, Webster S, Wegrzyniak B, Wenk G, Wyss-Coray T. Inflammation and Alzheimer’s disease. Neurobiol Aging 21, 383–421, 2000.10.1016/S0197-4580(00)00124-X]Open DOISearch in Google Scholar
[Baglietto-Vargas D, Chen Y, Suh D, Ager RR, Rodriguez-Ortiz CJ, Medeiros R, Myczek K, Green KN, Baram TZ, LaFerla FM. Short-term modern life-like stress exacerbates Abeta-pathology and synapse loss in 3xTg-AD mice. J Neurochem 134, 915–926, 2015.10.1111/jnc.13195479211826077803]Search in Google Scholar
[Biber K, Neumann H, Inoue K, Boddeke HW. Neuronal ‘On’ and ‘Off’ signals control microglia. Trends Neurosci 30, 596–602, 2007.1795092610.1016/j.tins.2007.08.00717950926]Search in Google Scholar
[Bidzhekov K, Zernecke A, Weber C. MCP-1 induces a novel transcription factor with proapoptotic activity. Circ Res 98, 1107–1109, 2006.10.1161/01.RES.0000223483.12225.8016690887]Search in Google Scholar
[Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 8, 57–69, 2007.10.1038/nrn203817180163]Search in Google Scholar
[Catania C, Sotiropoulos I, Silva R, Onofri C, Breen KC, Sousa N, Almeida OF. The amyloidogenic potential and behavioral correlates of stress. Mol Psychiatry 14, 95–105, 2009.1791224910.1038/sj.mp.400210117912249]Search in Google Scholar
[Erta M, Quintana A, Hidalgo J. Interleukin-6, a major cytokine in the central nervous system. Int J Biol Sci 8, 1254–1266, 2012.10.7150/ijbs.4679349144923136554]Search in Google Scholar
[Filipcik P, Novak P, Mravec B, Ondicova K, Krajciova G, Novak M, Kvetnansky R. Tau protein phosphorylation in diverse brain areas of normal and CRH deficient mice: up-regulation by stress. Cell Mol Neurobiol 32, 837–845, 2012.2222243910.1007/s10571-011-9788-922222439]Search in Google Scholar
[Green KN, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM. Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer’s disease. J Neurosci 26, 9047–9056, 2006.10.1523/JNEUROSCI.2797-06.2006667533516943563]Open DOISearch in Google Scholar
[Guerriero F, Sgarlata C, Francis M, Maurizi N, Faragli A, Perna S, Rondanelli M, Rollone M, Ricevuti G. Neuroinflammation, immune system and Alzheimer disease: searching for the missing link. Aging Clin Exp Res 29, 821–831, 2017.10.1007/s40520-016-0637-z2771817327718173]Open DOISearch in Google Scholar
[Huang NQ, Jin H, Zhou SY, Shi JS, Jin F. TLR4 is a link between diabetes and Alzheimer’s disease. Behav Brain Res 316, 234–244, 2017.10.1016/j.bbr.2016.08.047]Search in Google Scholar
[Chong Y. Effect of a carboxy-terminal fragment of the Alzheimer’s amyloid precursor protein on expression of proinflammatory cytokines in rat glial cells. Life Sci 61, 2323–2333, 1997.10.1016/S0024-3205(97)00936-3]Open DOISearch in Google Scholar
[Krstic D, Madhusudan A, Doehner J, Vogel P, Notter T, Imhof C, Manalastas A, Hilfiker M, Pfister S, Schwerdel C, Riether C, Meyer U, Knuesel I. Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice. J Neuroinflammation 9, 151, 2012.2274775310.1186/1742-2094-9-151348316722747753]Search in Google Scholar
[Kvetnansky R, Mikulaj L. Adrenal and urinary catecholamines in rats during adaptation to repeated immobilization stress. Endocrinology 87, 738–743, 1970.10.1210/endo-87-4-7385453288]Search in Google Scholar
[Lai AY, McLaurin J. Clearance of amyloid-beta peptides by microglia and macrophages: the issue of what, when and where. Future Neurol 7, 165–176, 2012.10.2217/fnl.12.6338006422737039]Search in Google Scholar
[Le MH, Weissmiller AM, Monte L, Lin PH, Hexom TC, Natera O, Wu C, Rissman RA. Functional impact of corticotropin-releasing factor exposure on Tau phosphorylation and axon transport. PLoS One 11, e0147250, 2016.2679009910.1371/journal.pone.0147250472040226790099]Search in Google Scholar
[Liu X, Wu Z, Hayashi Y, Nakanishi H. Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation. Neuroscience 216, 133–142, 2012.10.1016/j.neuroscience.2012.04.05022554776]Search in Google Scholar
[Liu YZ, Wang YX, Jiang CL. Inflammation: The common pathway of stress-related diseases. Front Hum Neurosci 11, 316, 2017.10.3389/fnhum.2017.00316547678328676747]Open DOISearch in Google Scholar
[Marklund N, Farrokhnia N, Hanell A, Vanmechelen E, Enblad P, Zetterberg H, Blennow K, Hillered L. Monitoring of beta-amyloid dynamics after human traumatic brain injury. J Neurotrauma 31, 42–55, 2014.10.1089/neu.2013.296423829439]Search in Google Scholar
[Mecca C, Giambanco I, Donato R, Arcuri C. Microglia and aging: the role of the TREM2–DAP12 and CX3CL1CX3CR1 axes. Int J Mol Sci 19, 318, 2018.10.3390/ijms19010318579626129361745]Search in Google Scholar
[Modur V, Li Y, Zimmerman GA, Prescott SM, McIntyre TM. Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. J Clin Invest 100, 2752–2756, 1997.938973910.1172/JCI119821]Search in Google Scholar
[Moraes CF, Lins TC, Carmargos EF, Naves JO, Pereira RW, Nobrega OT. Lessons from genome-wide association studies findings in Alzheimer’s disease. Psychogeriatrics 12, 62–73, 2012.10.1111/j.1479-8301.2011.00378.x]Search in Google Scholar
[Muller UC, Deller T, Korte M. Not just amyloid: physiological functions of the amyloid precursor protein family. Nat Rev Neurosci 18, 281–298, 2017.10.1038/nrn.2017.29]Open DOISearch in Google Scholar
[Murakami N, Yamaki T, Iwamoto Y, Sakakibara T, Kobori N, Fushiki S, Ueda S. Experimental brain injury induces expression of amyloid precursor protein, which may be related to neuronal loss in the hippocampus. J Neurotrauma 15, 993–1003, 1998.10.1089/neu.1998.15.993]Open DOISearch in Google Scholar
[Nakano Y, Furube E, Morita S, Wanaka A, Nakashima T, Miyata S. Astrocytic TLR4 expression and LPS-induced nuclear translocation of STAT3 in the sensory circumventricular organs of adult mouse brain. J Neuroimmunol 278, 144–158, 2015.10.1016/j.jneuroim.2014.12.013]Search in Google Scholar
[Novak P, Cente M, Kosikova N, Augustin T, Kvetnansky R, Novak M, Filipcik P. Stress-induced alterations of immune profile in animals suffering by Tau protein-driven neurodegeneration. Cell Mol Neurobiol 38, 243–259, 2018.10.1007/s10571-017-0491-328405903]Open DOISearch in Google Scholar
[Piirainen S, Youssef A, Song C, Kalueff AV, Landreth GE, Malm T, Tian L. Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer’s disease: the emerging role for microglia? Neurosci Biobehav Rev 77, 148–164, 2017.10.1016/j.neubiorev.2017.01.046]Search in Google Scholar
[Ringheim GE, Szczepanik AM, Petko W, Burgher KL, Zhu SZ, Chao CC. Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex. Brain Res Mol Brain Res 55, 35–44, 1998.964595810.1016/S0169-328X(97)00356-2]Search in Google Scholar
[Rissman RA, Lee KF, Vale W, Sawchenko PE. Corticotropin-releasing factor receptors differentially regulate stressinduced tau phosphorylation. J Neurosci 27, 6552–6562, 2007.10.1523/JNEUROSCI.5173-06.2007]Open DOISearch in Google Scholar
[Romano M, Sironi M, Toniatti C, Polentarutti N, Fruscella P, Ghezzi P, Faggioni R, Luini W, van Hinsbergh V, Sozzani S, Bussolino F, Poli V, Ciliberto G, Mantovani A. Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity 6, 315–325, 1997.10.1016/S1074-7613(00)80334-9]Open DOISearch in Google Scholar
[Sathyanesan M, Haiar JM, Watt MJ, Newton SS. Restraint stress differentially regulates inflammation and glutamate receptor gene expression in the hippocampus of C57BL/6 and BALB/c mice. Stress 20, 197–204, 2017.2827415210.1080/10253890.2017.1298587]Search in Google Scholar
[Shen X, Chen J, Li J, Kofler J, Herrup K. Neurons in vulnerable regions of the Alzheimer’s disease brain display reduced ATM signaling. eNeuro 3, ENEURO.0124–0115.2016, 2016.10.1523/ENEURO.0124-15.2016]Search in Google Scholar
[Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3, 1101–1108, 2008.10.1038/nprot.2008.7318546601]Open DOISearch in Google Scholar
[Small SA, Duff K. Linking Abeta and tau in late-onset Alzheimer’s disease: a dual pathway hypothesis. Neuron 60, 534–542, 2008.10.1016/j.neuron.2008.11.007]Search in Google Scholar
[Spires-Jones TL, Hyman BT. The intersection of amyloid beta and tau at synapses in Alzheimer’s disease. Neuron 82, 756–771, 2014.10.1016/j.neuron.2014.05.004]Open DOISearch in Google Scholar
[White JD, Peterman JL, Hardy A, Eimerbrink MJ, Paulhus KC, Thompson MA, Chumley MJ, Boehm GW. Prior exposure to repeated peripheral LPS injections prevents further accumulation of hippocampal beta-amyloid. Brain Behav Immun 66, e12–e13, 2017.10.1016/j.bbi.2017.07.056]Search in Google Scholar
[Wohleb ES, McKim DB, Sheridan JF, Godbout JP. Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior. Front Neurosci 8, 447, 2014.10.3389/fnins.2014.00447]Search in Google Scholar
[Wolf Y, Yona S, Kim KW, Jung S. Microglia, seen from the CX3CR1 angle. Front Cell Neurosci 7, 26, 2013.10.3389/fncel.2013.00026]Search in Google Scholar
[Yamamoto M, Horiba M, Buescher JL, Huang D, Gendelman HE, Ransohoff RM, Ikezu T. Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition. Am J Pathol 166, 1475–1485, 2005.10.1016/S0002-9440(10)62364-4]Search in Google Scholar
[Yamamoto M, Kiyota T, Walsh SM, Ikezu T. Kinetic analysis of aggregated amyloid-beta peptide clearance in adult bone-marrow-derived macrophages from APP and CCL2 transgenic mice. J Neuroimmune Pharmacol 2, 213–221, 2007.10.1007/s11481-006-9049-818040846]Search in Google Scholar
[Yi MH, Zhang E, Kang JW, Shin YN, Byun JY, Oh SH, Seo JH, Lee YH, Kim DW. Expression of CD200 in alternative activation of microglia following an excitotoxic lesion in the mouse hippocampus. Brain Res 1481, 90–96, 2012.10.1016/j.brainres.2012.08.05322975132]Search in Google Scholar
[Zhang C, Kuo CC, Moghadam SH, Monte L, Campbell SN, Rice KC, Sawchenko PE, Masliah E, Rissman RA. Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer’s disease. Alzheimers Dement 12, 527–537, 2016.10.1016/j.jalz.2015.09.007486018226555315]Open DOISearch in Google Scholar
[Zhao J, O’Connor T, Vassar R. The contribution of activated astrocytes to Abeta production: implications for Alzheimer’s disease pathogenesis. J Neuroinflammation 8, 150, 2011.10.1186/1742-2094-8-150321600022047170]Search in Google Scholar
[Zhou L, Azfer A, Niu J, Graham S, Choudhury M, Adamski FM, Younce C, Binkley PF, Kolattukudy PE. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ Res 98, 1177–1185, 2006.10.1161/01.RES.0000220106.64661.71152342516574901]Search in Google Scholar