<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The plant mediated biogenic synthesis of nanoparticles is of magnificent concern due to its eco-benign and single pot nature. Here, <italic>Cinnamomum tamala</italic> (<italic>C. tamala</italic>) aqueous leaf extract was utilised for the silver nanoparticles’ (Ag NPs) synthesis. The phytoconstituents in the leaf extract were analysed by standard methods. These metabolites, especially carbohydrate polymers reduce Ag ions to Ag NPs accompanied by a reddish-brown coloration of the reaction mixture. The visual observation of intense brown colour is the first indication of the formation of Ag NPs. Various spectro-analytical techniques further characterise the Ag NPs. The green synthesised spherical Ag NPs were crystalline with an average size of 38 nm. The Ag NPs were scrutinised for antioxidant, antimicrobial and cytotoxic activity and obtained good results. The free radical scavenging was studied by 2, 2-Diphenyl-l-picrylhydrazyl (DPPH) assay. The antibacterial activity of Ag NPs was assessed against human pathogens, and it shown to have good antibacterial potency against a wide spectrum of bacteria. The cytotoxic activity against HEK-293T (human embryonic kidney) cell line was evaluated by 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay. These potent biological activities enable <italic>C. tamala</italic> capped Ag NPs to be suitable candidates for the future applications in various fields, predominantly clinical and biomedical.</p>
</abstract>

The plant mediated biogenic synthesis of nanoparticles is of magnificent concern due to its eco-benign and single pot nature. Here, Cinnamomum tamala (C. tamala) aqueous leaf extract was utilised for the silver nanoparticles’ (Ag NPs) synthesis. The phytoconstituents in the leaf extract were analysed by standard methods. These metabolites, especially carbohydrate polymers reduce Ag ions to Ag NPs accompanied by a reddish-brown coloration of the reaction mixture. The visual observation of intense brown colour is the first indication of the formation of Ag NPs. Various spectro-analytical techniques further characterise the Ag NPs. The green synthesised spherical Ag NPs were crystalline with an average size of 38 nm. The Ag NPs were scrutinised for antioxidant, antimicrobial and cytotoxic activity and obtained good results. The free radical scavenging was studied by 2, 2-Diphenyl-l-picrylhydrazyl (DPPH) assay. The antibacterial activity of Ag NPs was assessed against human pathogens, and it shown to have good antibacterial potency against a wide spectrum of bacteria. The cytotoxic activity against HEK-293T (human embryonic kidney) cell line was evaluated by 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay. These potent biological activities enable C. tamala capped Ag NPs to be suitable candidates for the future applications in various fields, predominantly clinical and biomedical.

Facile Green Synthesis of <italic>Cinnamomum tamala</italic> Extract Capped Silver Nanoparticles and its Biological Applications

Department of Chemistry, School of Physical Sciences

Department of Biochemistry and Molecular Biology, School of Biological Sciences

School of Biological Sciences, Central University of Kerala

Ecological Chemistry and Engineering S

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Facile Green Synthesis of  Extract Capped Silver Nanoparticles and its Biological Applications

The plant mediated biogenic synthesis of nanoparticles is of magnificent concern due to its eco-benign and single pot nature. Here, Cinnamomum tamala (C....

Facile Green Synthesis of Cinnamomum tamala Extract Capped Silver Nanoparticles and its Biological Applications

Data publikacji: 10 kwi 2023

Zakres stron: 7 - 21

DOI: https://doi.org/10.2478/eces-2023-0001

Słowa kluczowe
green synthesis, silver nanoparticles, antioxidant, antibacterial, cytotoxicity

© 2023 Sajina Narath et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Facile Green Synthesis of Cinnamomum tamala Extract Capped Silver Nanoparticles and its Biological Applications

Data publikacji: 10 kwi 2023

Zakres stron: 7 - 21

DOI: https://doi.org/10.2478/eces-2023-0001

Słowa kluczowegreen synthesis, silver nanoparticles, antioxidant, antibacterial, cytotoxicity

© 2023 Sajina Narath et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Słowa kluczowe
green synthesis, silver nanoparticles, antioxidant, antibacterial, cytotoxicity