Effect of the inferior alveolar nerve block injection versus maxillary infiltration with two local anesthetic agents on cardiovascular parameters: A randomized comparative double-blind clinical trial

1 Torres-Lagares D, Serrera-Figallo MÁ, Machuca-Portillo G, Corcuera-Flores JR, Machuca-Portillo C, Castillo-Oyagüe R, et al. Cardiovascular effect of dental anesthesia with articaine (40 mg with epinefrine 0.5 mg% and 40 mg with epinefrine 1 mg%) versus mepivacaine (30 mg and 20 mg with epinefrine 1 mg%) in medically compromised cardiac patients: A cross-over, randomized, single blinded study. Med Oral Patol Oral Cir Bucal. 2012;17(4):655-60. Search in Google Scholar

2 Sharifi R, Nazari H, Bolourchi P, Khazaei S, Parirokh M. The most painful site of maxillary anterior infiltrations. Dent Res J. 2016;13(6):539-43. Search in Google Scholar

3 Troullos ES, Goldstein DS, Hargreaves KM, Dionne RA. Plasma epinephrine levels and cardiovascular response to high administered doses of epinephrine in local anesthesia. Anesth Progr. 1987;34(1):10-3. Search in Google Scholar

4 Abu-Mostafa N, Al-Showaikhat F, Al-Shubbar F, Al-Zawad K, Al-Zawad F. Hemodynamic changes following injection of local anesthetics with different concentrations of epinephrine during simple tooth extraction: A prospective randomized clinical trial. J Clin Exp Dent. 2015;7(4):471-6. Search in Google Scholar

5 Scarparo HC, Maia RN, de Gois SR, Costa FW, Ribeiro TR, Soares EC. Effects of mepivacaine 2% with epinephrine in the cardiovascular activity of patients undergoing third molar surgery: a prospective clinical study. J Craniofac Surg. 2014;25(1):9-12. Search in Google Scholar

6 Becker DE, Reed KL. Local anesthetics: review of pharmacological considerations. Anesth Prog. 2012;59(2):90-102. Search in Google Scholar

7 Saxena P, Gupta SK, Newaskar V, Chandra A. Advances in dental local anesthesia techniques and devices: An update. Natl J Maxillofac Surg. 2013;4(1):19-4. Search in Google Scholar

8 de Morais HH, de Santana Santos T, da Costa Araújo FA, de Freitas Xavier RL, Vajgel A, de Holanda Vasconcellos RJ. Hemodynamic changes comparing 2% lidocaine and 4% articaine with epinephrine 1: 100,000 in lower third molar surgery. J Craniofac Surg. 2012;23(4):1204-11. Search in Google Scholar

9 Balasubramaniyan N, Rayapati DK, Puttiah RH, Tavane P, Singh SE, Rangan V, Kalakunta PR. Evaluation of anxiety induced cardiovascular response in known hypertensive patients undergoing exodontia-a prospective study. J Clin Diagn Res. 2016;10(8):123-7. Search in Google Scholar

10 Managutti A, Prakasam M, Puthanakar N, Menat S, Shah D, Patel H. Comparative analysis of local anesthesia with 2 different concentrations of adrenaline: a randomized and single blind study. J Int Oral Health. 2015;7(3):24-7. Search in Google Scholar

11 Meechan JG, Cole B, Welbury RR. Anaesthesia: The influence of two different dental local anaesthetic solutions on the haemo-dynamic responses of children undergoing restorative dentistry: a randomised, single-blind, split-mouth study. Br Dent J. 2001;190(9):502-4. Search in Google Scholar

12 Sanadhya YK, Sanadhya S, Jalihal S, Nagarajappa R, Ramesh G, Tak M. Hemodynamic, ventilator, and ECG changes in pediatric patients undergoing extraction. J Indian Soc Pedod Prev Dent. 2013;31(1):10-6. Search in Google Scholar

13 Raja DC, Kapoor A, Sinha A, Kashyap S, Khanna R, Kumar S, Garg N, Tewari S, Goel P. Heart rate manipulation in dilated cardiomyopathy: assessing the role of ivabradine. Indian Heart J. 2018;70(2):246-51. Search in Google Scholar

14 Ezmek B, Arslan A, Delilbasi C, Sencift K. Comparison of hemodynamic effects of lidocaine, prilocaine and mepivacaine solutions without vasoconstrictor in hypertensive patients. J Appl Oral Sci. 2010;18(4):354-9. Search in Google Scholar

15 Lequeux B, Uzan C, Rehman MB. Does resting heart rate measured by the physician reflect the patient’s true resting heart rate? White-coat heart rate. Indian Heart J. 2018;70(1):93-8. Search in Google Scholar

16 Fu Y, Liu J. System design for wearable blood oxygen saturation and pulse measurement device. Procedia Manuf. 2015;3:1187-94. Search in Google Scholar

17 Santos CF, Modena KC, Giglio FP, Sakai VT, Calvo AM, Colombini BL. Epinephrine concentration (1: 100,000 or 1: 200,000) does not affect the clinical efficacy of 4% articaine for lower third molar removal: a double-blind, randomized, crossover study. J Oral Maxillofac Surg. 2007;65(12):2445-52. Search in Google Scholar

18 Murillo‐Benítez M, Martín‐González J, Jiménez‐Sánchez MC, Cabanillas‐Balsera D, Velasco‐Ortega E, Segura‐Egea JJ. Association between dental anxiety and intraoperative pain during root canal treatment: a cross‐sectional study. Int Endod J. 2020;53(4):447-54. Search in Google Scholar