[Arciszewski M.B., Nowakowski Z., Wasowicz K., Całka J. (2009). Expression of vasoactive intestinal polypeptide, substance P and neuropeptide Y in jejunal enteric nerves is altered in rabbits suffering from long term Trichinella spiralis infection: an immunohistochemical study. Vet. Med., 54: 589597.10.17221/66/2009-VETMED]Search in Google Scholar
[Bertram C.E., Hanson M.A. (2002). Prenatal programming of postnatal endocrine responses by glucocorticoids. Reproduction, 124: 459467.10.1530/rep.0.1240459]Search in Google Scholar
[Bik W. (2007). Vasoactive intestinal peptide-immunomodulatory factor and its role in respiratory diseases (in Polish). Post. Nauk Med., 10: 408413.]Search in Google Scholar
[Blicharski T., Tomaszewska E., Dobrowolski P., Hułas-Stasiak M., Muszyński S. (2017). A metabolite of leucine (β-hydroxy-β-methylbutyrate) given to sows during pregnancy alters bone development of their newborn offspring by hormonal modulation. PLoS One, 12: e0179693.10.1371/journal.pone.0179693]Search in Google Scholar
[Czech A., Grela R.E., Kiesz M., Kłys S. (2020). Biochemical and haematological blood parameters of sows and piglets fed a diet with a dried fermented rapeseed meal. Ann. Anim. Sci., 20: 535–550.10.2478/aoas-2019-0079]Search in Google Scholar
[Delgado M., Pozo D., Ganea D. (2004). The significance of vasoactive intestinal peptide in immunomodulation. Pharmacol. Rev., 56: 249290.10.1124/pr.56.2.7]Search in Google Scholar
[Dobrowolski P., Muszyński S., Donaldson J., Jakubczak A., Żmuda A., Taszkun I., Rycerz K., Mielnik-Błaszczak M., Kuc D., Tomaszewska E. (2021). The effects of prenatal supplementation with β-hydroxy-β-methylbutyrate and/or alpha-ketoglutaric acid on the development and maturation of mink intestines are dependent on the number of pregnancies and the sex of the offspring. Animals, 11: 1468.10.3390/ani11051468]Search in Google Scholar
[Duan Y., Li F., Song B., Zheng C., Zhong Y., Xu K., Kong X., Yin Y., Wang W., Shu G. (2019). β-hydroxy-β-methyl butyrate, but not α-ketoisocaproate and excess leucine, stimulates skeletal muscle protein metabolism in growing pigs fed low protein diets. J. Funct. Foods, 52: 34–42.10.1016/j.jff.2018.10.029]Search in Google Scholar
[El Karim I.A., Linden G.J., Orr D.F., Lundy F.T. (2008). Antimicrobial activity of neuropeptides against a range of micro-organisms from skin, oral, respiratory and gastrointestinal tract sites. J. Neuroimmunol., 200: 1116.10.1016/j.jneuroim.2008.05.014]Search in Google Scholar
[Flummer C., Theil P.K. (2012). Effect of β-hydroxy β-methyl butyrate supplementation of sows in late gestation and lactation on sow production of colostrum and milk and piglet performance. J. Anim. Sci., 90: 372–374.10.2527/jas.53971]Search in Google Scholar
[Francis D.H. (1999). Colibacillosis in pigs and its diagnosis. Swine Health Prod., 7: 241244.]Search in Google Scholar
[Friedman J. (2014). 20 years of leptin: leptin at 20: an overview. J. Endocrinol., 223: T1T8.10.1530/JOE-14-0405]Search in Google Scholar
[Gonzalez-Rey E., Delgado M. (2005). Role of vasoactive intestinal peptide in inflammation and autoimmunity. Curr. Opin. Investig. Drugs., 6: 11161123.]Search in Google Scholar
[Grela E.R., Skomiał J. (2015). Nutritional recommendations and nutritional value of feed for pigs, 2nd ed. Institute of Physiology and Animal Nutrition of Polish Academy of Science, Jabłonna, Poland, pp. 195.]Search in Google Scholar
[Groschwitz K.R., Hogan S.P. (2009). Intestinal barrier function: molecular regulation and disease pathogenesis. J. Allergy Clin. Immunol., 124: 320.10.1016/j.jaci.2009.05.038]Search in Google Scholar
[Hales C.N., Barker D.J., Clark P.M., Cox L.J., Fall C., Osmond C., Winter P.D. (1991). Fetal and infant growth and impaired glucose tolerance at age 64. Br. Med. J., 303: 10191022.10.1136/bmj.303.6809.1019]Search in Google Scholar
[Hao Y., Jackson J.R., Wang Y., Edens N., Pereira S.L., Alway S.E. (2011). β-Hydroxy-β-methylbutyrate reduces myonuclear apoptosis during recovery from hind limb suspension-induced muscle fiber atrophy in aged rats. Am. J. Physiol. Regul. Integr. Comp. Physiol., 301: R701R715.10.1152/ajpregu.00840.2010]Search in Google Scholar
[Hułas-Stasiak M., Jakubowicz-Gil J., Dobrowolski P., Grzesiak M., Muszyński S., Świątkiewicz M., Tomaszewska E. (2020). Regulation of folliculogenesis by growth factors in piglet ovary exposed prenatally to β-hydroxy-β-methylbutyrate (HMB). Ann. Anim. Sci., 20: 899–917.10.2478/aoas-2020-0026]Search in Google Scholar
[Lis I., Bogdański P., Karolkiewicz J. (2014). The effect of β-hydroxy-β-methylbutyrate (HMB) on muscle protein metabolism. Farm Współ., 7: 3241.]Search in Google Scholar
[Luppi A. (2017). Swine enteric colibacillosis: diagnosis, therapy and antimicrobial resistance. Porc. Health Manag., 3: 16.10.1186/s40813-017-0063-4]Search in Google Scholar
[Matthews S.G. (2001). Antenatal glucocorticoids and the development brain: mechanisms of action. Semin Neonatol., 6: 309317.10.1053/siny.2001.0066]Search in Google Scholar
[Milart P., Paluszkiewicz P., Dobrowolski P., Tomaszewska E., Smolińska K., Dębińska I., Gaweł K., Walczak K., Bednarski J., Turska M., Raban M., Kocki T., Turski W.A. (2019). Kynurenic acid as the neglected ingredient of commercial baby formulas. Sci. Rep., 9: 6108.10.1038/s41598-019-42646-4]Search in Google Scholar
[Mou Q., Yang H-S., Yin Y-L., Huang P-F. (2019). Amino acids influencing intestinal development and health of the piglets. Animals, 9: 302.10.3390/ani9060302]Search in Google Scholar
[Nissen S., Abumrad N.N. (1997). Nutritional role of the leucine metabolite β-hydroxy-β-methylbutyrate (HMB). J. Nutr. Biochem., 8: 300311.10.1016/S0955-2863(97)00048-X]Search in Google Scholar
[Nissen S., Faidley T.D., Zimmerman D.R., Izard R., Fisher C.T. (1994). Colostral milk fat percentage and pig performance are enhanced by feeding the leucine metabolite beta-hydroxy-beta-methyl butyrate to sows. J. Anim. Sci., 72: 2331–2337.10.2527/1994.7292331x]Search in Google Scholar
[Nissen S., Sharp R.L., Panton L., Vukovich M., Trappe S., Fuller J.C. Jr. (2000). Beta-hydroxy-methylbutyrate (HMB) supplementation in humans is safe and decrease cardiovascular risk factors. J. Nutr., 130: 19371945.10.1093/jn/130.8.1937]Search in Google Scholar
[Nowak P., Zaworska-Zakrzewska A., Frankiewicz A., Kasprowicz-Potocka M. (2021). The effects and mechanisms of acids on the health of piglets and weaners – a review. Ann. Anim. Sci., 21: 433–455.10.2478/aoas-2020-0088]Search in Google Scholar
[Park H.K., Ahima R.S. (2014). Leptin signaling. F1000Prime Rep., 6: 73.10.12703/P6-73]Search in Google Scholar
[Pearson P.Y., O’Connor D.M., Schwartz M.Z. (2001). Novel effect of leptin on small intestine adaptation. J. Surg. Res., 97: 192–195.10.1006/jsre.2001.6153]Search in Google Scholar
[Rudyk H., Tomaszewska E., Arciszewski M.B., Muszyński S., Tomczyk-Warunek A., Dobrowolski P., Donaldson J., Brezvyn O., Kotsyumbas I. (2020). Histomorphometrical changes in intestine structure and innervation following experimental fumonisins intoxication in male Wistar rats. Pol. J. Vet. Sci., 23: 7788.]Search in Google Scholar
[Said S.I. (1991). Vasoactive intestinal polypeptide: biologic role in health and disease. Trends Endocrinol Metab., 2: 107–112.10.1016/S1043-2760(05)80006-2]Search in Google Scholar
[Schneider C.A., Rasband W.S., Eliceiri K.W. (2012). NIH Image to ImageJ: 25 years of image analysis. Nat. Methods, 9: 671–675.10.1038/nmeth.2089]Search in Google Scholar
[So K-W., Ng P-C. (2005). Treatment and prevention of neonatal osteopenia. Curr. Pediatr., 15: 106–113.10.1016/j.cupe.2004.12.011]Search in Google Scholar
[Suvarna S.K., Layton C., Bancroft J.D. (2013). Bancroft’s theory and practice of histological techniques, 7th ed. Churchill Livingstone, New York, NY, USA.]Search in Google Scholar
[Świetlicka I., Muszyński S., Tomaszewska E., Dobrowolski P., Kwaśniewska A., Świetlicki M., Skic A., Gołacki K. (2016). Prenatally administered HMB modifies the enamel surface roughness in spiny mice offspring: An atomic force microscopy study. Arch. Oral Biol., 70: 2431.10.1016/j.archoralbio.2016.06.001]Search in Google Scholar
[Tatara M.R., Śliwa E., Krupski W. (2007). Prenatal programming of skeletal development in the offspring: effects of maternal treatment with β-hydroxy-β-methylbutyrate (HMB) on femur properties in pigs at slaughter age. Bone, 40: 1615–1622.10.1016/j.bone.2007.02.018]Search in Google Scholar
[Tomaszewska E., Dobrowolski P., Puzio I., Prost Ł., Kurlak P., Sawczuk P., Badzian B., Hułas-Stasiak M., Kostro K. (2014). Acrylamide-induced prenatal programming intestine structure in guinea pig. J. Physiol. Pharmacol., 65: 107–115.]Search in Google Scholar
[Tomaszewska E., Dobrowolski P., Świetlicka I., Muszyński S., Kostro K., Jakubczak A., Taszkun I., Żmuda A., Rycerz, K., Blicharski T., Jaworska-Adamu J. (2018). Effects of maternal treatment with β-hydroxy-β-metylbutyrate and 2-oxoglutaric acid on femur development in offspring of minks of the standard dark brown type. J. Anim. Physiol. Anim. Nutr., 102: e299–e308.10.1111/jpn.12742]Search in Google Scholar
[Tomaszewska E., Muszyński S., Dobrowolski P., Wiącek D., Tomczyk-Warunek A., Świetlicka I., Pierzynowski G.P. (2019). Maternal HMB treatment affects bone and hyaline cartilage development in their weaned piglets via the leptin/osteoprotegerin system. J. Anim. Physiol. Anim. Nutr., 103: 626–643.10.1111/jpn.13060]Search in Google Scholar
[Tomaszewska E., Dobrowolski P., Puzio I., Donaldson J., Muszyński S. (2020). Acrylamide-induced prenatal programming of bone structure in mammal model. Ann. Anim. Sci., 20: 1257–1287.10.2478/aoas-2020-0044]Search in Google Scholar
[Tomaszewska E., Burmańczuk N., Dobrowolski P., Świątkiewicz M., Donaldson J., Burmańczuk A., Mielnik-Błaszczak M., Kuc D., Milewski S., Muszyński S. (2021). The protective role of alpha-ketoglutaric acid on the growth and bone development of experimentally induced perinatal growth-retarded piglets. Animals, 11: 137.10.3390/ani11010137]Search in Google Scholar
[Tomczyk-Warunek A., Blicharski T., Jarecki J., Dobrowolski P., Muszyński S., Tomaszewska E., Rovati L.C. (2021). The effect of maternal HMB supplementation on bone mechanical and geometrical properties, as well as histomorphometry and immunolocalization of VEGF, TIMP2, MMP13, BMP2 in the bone and cartilage tissue of the humerus of their newborn piglets. PloS One, 16: 2 e024–0642.10.1371/journal.pone.0240642]Search in Google Scholar
[Vu J.P., Larauche M., Flores M., Luong L., Norris J., Oh S., Liang L.J., Waschek J., Pisegna J.R., Germano P.M. (2015). Regulation of appetite, body composition, and metabolic hormones by vasoactive intestinal polypeptide (VIP). J. Mol. Neurosci., 56: 377–387.10.1007/s12031-015-0556-z]Search in Google Scholar
[Winzell M.S., Ahrén B. (2007). Role of VIP and PACAP in islet function. Peptides, 28: 1805–1813.10.1016/j.peptides.2007.04.024]Search in Google Scholar
[Xiong X., Tan B., Song M., Ji P., Kim K., Yin Y., Liu Y. (2019). Nutritional intervention for the intestinal development and health of weaned pigs. Front. Vet. Sci., 6: 46.10.3389/fvets.2019.00046]Search in Google Scholar
[Yavas C., Yavas G., Acar H., Toy H., Yuce D., Akyurek S., Ata O. (2013). Amelioration of radiation-induced acute inflammation and mucosal atrophy by beta-hydroxy-beta-methylbutyrate, L-glutamıne, and L-argınıne: results of an experimental study. Support Care Cancer, 21: 883–888.10.1007/s00520-012-1601-x]Search in Google Scholar
[Zheng C., Song B., Duan Y., Zhong Y., Yan Z., Zhang S., Li F. (2020). Dietary β-hydroxy-β-methylbutyrate improves intestinal function in weaned piglets after lipopolysaccharide challenge. Nutrition, 78: 110839.10.1016/j.nut.2020.110839]Search in Google Scholar