<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Artificial Intelligence (AI) has gained a prominent role in the medical industry. The rapid development of the computer science field has caused AI to become a meaningful part of modern healthcare. Image-based analysis involving neural networks is a very important part of eye diagnoses. In this study, a new approach using Convolutional Gated Recurrent Units (GRU) U-Net was proposed for the classifying healthy cases and cases with retinitis pigmentosa (RP) and cone–rod dystrophy (CORD). The basis for the classification was the location of pigmentary changes within the retina and fundus autofluorescence (FAF) pattern, as the posterior pole or the periphery of the retina may be affected. The dataset, gathered in the Chair and Department of General and Pediatric Ophthalmology of Medical University in Lublin, consisted of 230 ultra-widefield pseudocolour (UWFP) and ultra-widefield FAF images, obtained using the Optos 200TX device (Optos PLC). The data were divided into three categories: healthy subjects (50 images), patients with CORD (48 images) and patients with RP (132 images). For applying deep learning classification, which rely on a large amount of data, the dataset was artificially enlarged using augmentation involving image manipulations. The final dataset contained 744 images. The proposed Convolutional GRU U-Net network was evaluated taking account of the following measures: accuracy, precision, sensitivity, specificity and F1. The proposed tool achieved high accuracy in a range of 91.00%–97.90%. The developed solution has a great potential in RP diagnoses as a supporting tool.</p>
</abstract>

Artificial Intelligence (AI) has gained a prominent role in the medical industry. The rapid development of the computer science field has caused AI to become a meaningful part of modern healthcare. Image-based analysis involving neural networks is a very important part of eye diagnoses. In this study, a new approach using Convolutional Gated Recurrent Units (GRU) U-Net was proposed for the classifying healthy cases and cases with retinitis pigmentosa (RP) and cone–rod dystrophy (CORD). The basis for the classification was the location of pigmentary changes within the retina and fundus autofluorescence (FAF) pattern, as the posterior pole or the periphery of the retina may be affected. The dataset, gathered in the Chair and Department of General and Pediatric Ophthalmology of Medical University in Lublin, consisted of 230 ultra-widefield pseudocolour (UWFP) and ultra-widefield FAF images, obtained using the Optos 200TX device (Optos PLC). The data were divided into three categories: healthy subjects (50 images), patients with CORD (48 images) and patients with RP (132 images). For applying deep learning classification, which rely on a large amount of data, the dataset was artificially enlarged using augmentation involving image manipulations. The final dataset contained 744 images. The proposed Convolutional GRU U-Net network was evaluated taking account of the following measures: accuracy, precision, sensitivity, specificity and F1. The proposed tool achieved high accuracy in a range of 91.00%–97.90%. The developed solution has a great potential in RP diagnoses as a supporting tool.

Application of Convolutional Gated Recurrent Units U-Net for Distinguishing between Retinitis Pigmentosa and Cone–Rod Dystrophy

Faculty of Electrical Engineering and Computer Science, Department of Computer Science

Faculty of Medicine, Chair and Department of General and Pediatric Ophthalmology

Acta Mechanica et Automatica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Artificial Intelligence (AI) has gained a prominent role in the medical industry. The rapid development of the computer science field has caused AI to become a...

Application of Convolutional Gated Recurrent Units U-Net for Distinguishing between Retinitis Pigmentosa and Cone–Rod Dystrophy

Data publikacji: 25 lip 2024

Zakres stron: 505 - 513

Otrzymano: 22 lip 2023

Przyjęty: 29 sty 2024

DOI: https://doi.org/10.2478/ama-2024-0054

Słowa kluczowe
retinitis pigmentosa, convolutional GRU U-Net, classification, UWFP, UWFAF, deep learning

© 2024 Maria Skublewska-Paszkowska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Application of Convolutional Gated Recurrent Units U-Net for Distinguishing between Retinitis Pigmentosa and Cone–Rod Dystrophy

Data publikacji: 25 lip 2024

Zakres stron: 505 - 513

Otrzymano: 22 lip 2023

Przyjęty: 29 sty 2024

DOI: https://doi.org/10.2478/ama-2024-0054

Słowa kluczoweretinitis pigmentosa, convolutional GRU U-Net, classification, UWFP, UWFAF, deep learning

© 2024 Maria Skublewska-Paszkowska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Słowa kluczowe
retinitis pigmentosa, convolutional GRU U-Net, classification, UWFP, UWFAF, deep learning