Bdellovibrio bacteriovorus: More than Just a Bacterial Hunter

1 Abram D., Castro e Melo J., Chou D.: Penetration of Bdellovibrio bacteriovorus into host cells. J. Bacteriol. 118(2), 663–680 (1974) AbramD. Castro e MeloJ. ChouD. Penetration of Bdellovibrio bacteriovorus into host cells J. Bacteriol. 118 2 663 680 1974 10.1128/jb.118.2.663-680.19742468024208138 Search in Google Scholar

2 Baker M., Negus D., Raghunathan D., Radford P., Moore C., Clark G., Diggle M., Tyson J., Twycross J., Sockett R.E.: Measuring and modelling the response of Klebsiella pneumoniae KPC prey to Bdellovibrio bacteriovorus predation, in human serum and defined buffer. Sci. Rep. 7, 1–18 (2017) BakerM. NegusD. RaghunathanD. RadfordP. MooreC. ClarkG. DiggleM. TysonJ. TwycrossJ. SockettR.E. Measuring and modelling the response of Klebsiella pneumoniae KPC prey to Bdellovibrio bacteriovorus predation, in human serum and defined buffer Sci. Rep. 7 1 18 2017 10.1038/s41598-017-08060-4556709528827526 Search in Google Scholar

3 Brandt J-M., Mahmoud K., Koval S., MacDonald S., Medley J.: Antimicrobial agents and low-molecular weight polypeptides affect polyethylene wear in knee simulator testing. Tribol. Int. 65, 97–104 (2013) BrandtJ-M. MahmoudK. KovalS. MacDonaldS. MedleyJ. Antimicrobial agents and low-molecular weight polypeptides affect polyethylene wear in knee simulator testing Tribol. Int. 65 97 104 2013 10.1016/j.triboint.2013.02.019 Search in Google Scholar

4 Bratanis E., Molina H., Naegeli A., Collin M., Lood R.: BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies. Appl. Environ. Microbiol. 83, e03037–16 (2017) BratanisE. MolinaH. NaegeliA. CollinM. LoodR. BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies Appl. Environ. Microbiol. 83 e03037 16 2017 10.1128/AEM.03037-16528881327940543 Search in Google Scholar

5 Bukowska-Faniband E., Andersson T., Lood R.: Studies on Bd0934 and Bd3507, two secreted nucleases from Bdellovibrio bacteriovorus, reveal sequential release of nucleases during the predatory cycle. J. Bacteriol. 202, e00150–20 (2020) Bukowska-FanibandE. AnderssonT. LoodR. Studies on Bd0934 and Bd3507, two secreted nucleases from Bdellovibrio bacteriovorus, reveal sequential release of nucleases during the predatory cycle J. Bacteriol. 202 e00150 20 2020 10.1128/JB.00150-20792507432601070 Search in Google Scholar

6 Burnham J.C., Hashimoto T., Conti S.F.: Electron microscopic observations on the penetration of Bdellovibrio bacteriovorus into gram-negative bacterial hosts. J. Bacteriol. 96(4), 1366–1381 (1968) BurnhamJ.C. HashimotoT. ContiS.F. Electron microscopic observations on the penetration of Bdellovibrio bacteriovorus into gram-negative bacterial hosts J. Bacteriol. 96 4 1366 1381 1968 10.1128/jb.96.4.1366-1381.19682524614879563 Search in Google Scholar

7 Cao H., An J., Zheng W., He S.: Vibrio cholerae pathogen from the freshwater-cultured whiteleg shrimp Penaeus vannamei and control with Bdellovibrio bacteriovorus. J. Invertebr. Pathol. 130, 13–20 (2015) CaoH. AnJ. ZhengW. HeS. Vibrio cholerae pathogen from the freshwater-cultured whiteleg shrimp Penaeus vannamei and control with Bdellovibrio bacteriovorus J. Invertebr. Pathol. 130 13 20 2015 10.1016/j.jip.2015.06.00226146226 Search in Google Scholar

8 Cao H., Wang H., Yu J., An J., Chen J.: Encapsulated bdellovibrio powder as a potential bio-disinfectant against whiteleg shrimp-pathogenic vibrios. Microorganisms, 7(8), 244 (2019) CaoH. WangH. YuJ. AnJ. ChenJ. Encapsulated bdellovibrio powder as a potential bio-disinfectant against whiteleg shrimp-pathogenic vibrios Microorganisms 7 8 244 2019 10.3390/microorganisms7080244672271631394792 Search in Google Scholar

9 Carbonnelle E., H elaine S., Prouvensier L., Nassif X, Pelicic V.: Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and function. Mol. Microbiol. 55(1), 54–64 (2005) CarbonnelleE. H elaineS. ProuvensierL. NassifX PelicicV. Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and function Mol. Microbiol. 55 1 54 64 2005 10.1111/j.1365-2958.2004.04364.x15612916 Search in Google Scholar

10 Chanyi R.M., Koval S.F.: Role of type IV Pili in predation by Bdellovibrio bacteriovorus. PLoS One, 9(11), e113404 (2014) ChanyiR.M. KovalS.F. Role of type IV Pili in predation by Bdellovibrio bacteriovorus PLoS One 9 11 e113404 2014 10.1371/journal.pone.0113404423744525409535 Search in Google Scholar

11 Chen X., Yi H., Liu S., Zhang Y., Su Y., Liu X., Bi S., Lai H., Zeng Z., Li G.: Promotion of pellet-feed feeding in mandarin fish (Siniperca chuatsi) by Bdellovibrio bacteriovorus is influenced by immune and intestinal flora. Aquaculture, 542, 736864 (2021) ChenX. YiH. LiuS. ZhangY. SuY. LiuX. BiS. LaiH. ZengZ. LiG. Promotion of pellet-feed feeding in mandarin fish (Siniperca chuatsi) by Bdellovibrio bacteriovorus is influenced by immune and intestinal flora Aquaculture 542 736864 2021 10.1016/j.aquaculture.2021.736864 Search in Google Scholar

12 Dashiff A., Junka R., Libera M., Kadouri D.: Predation of human pathogens by the predatory bacteria Micavibrio aeruginosavorus and Bdellovibrio bacteriovorus. J. Appl. Microbiol. 110, 431–444 (2011) DashiffA. JunkaR. LiberaM. KadouriD. Predation of human pathogens by the predatory bacteria Micavibrio aeruginosavorus and Bdellovibrio bacteriovorus J. Appl. Microbiol. 110 431 444 2011 10.1111/j.1365-2672.2010.04900.x21114596 Search in Google Scholar

13 Dashiff A., Keeling T.G., Kadouri D.E.: Inhibition of predation by Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus via host cell metabolic activity in the presence of carbohydrates. Appl. Environ. Microbiol. 77(7), 2224–2231 (2011) DashiffA. KeelingT.G. KadouriD.E. Inhibition of predation by Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus via host cell metabolic activity in the presence of carbohydrates Appl. Environ. Microbiol. 77 7 2224 2231 2011 10.1128/AEM.02565-10306743621317250 Search in Google Scholar

14 Deeg C.M., Le T.T., Zimmer M.M., Suttle C.A.: From the inside out: An epibiotic Bdellovibrio predator with an expanded genomic complement. J. Bacteriol. 202, e00565–19 (2020) DeegC.M. LeT.T. ZimmerM.M. SuttleC.A. From the inside out: An epibiotic Bdellovibrio predator with an expanded genomic complement J. Bacteriol. 202 e00565 19 2020 10.1128/JB.00565-19709913132015145 Search in Google Scholar

15 Dharani S., Kim D.H., Shanks R.M., Doi Y., Kadouri D.E.: Susceptibility of colistin-resistant pathogens to predatory bacteria. Res. Microbiol. 169, 52–55 (2018) DharaniS. KimD.H. ShanksR.M. DoiY. KadouriD.E. Susceptibility of colistin-resistant pathogens to predatory bacteria Res. Microbiol. 169 52 55 2018 10.1016/j.resmic.2017.09.001781523028919044 Search in Google Scholar

16 Dori-Bachash M., Dassa B., Pietrokovski S., Jurkevitch E.: Proteome-based comparative analyses of growth stages reveal new cell cycle-dependent functions in the predatory bacterium Bdellovibrio bacteriovorus. Appl. Environ. Microbiol. 74(23), 7152–7162 (2008) Dori-BachashM. DassaB. PietrokovskiS. JurkevitchE. Proteome-based comparative analyses of growth stages reveal new cell cycle-dependent functions in the predatory bacterium Bdellovibrio bacteriovorus Appl. Environ. Microbiol. 74 23 7152 7162 2008 10.1128/AEM.01736-08259291018836011 Search in Google Scholar

17 Duncan M.C., Forbes J.C., Nguyen Y., Shull L.M., Gillette R.K., Lazinski D.W., Ali A., Shanks R.M., Kadouri D.E., Camilli A.: Vibrio cholerae motility exerts drag force to impede attack by the bacterial predator Bdellovibrio bacteriovorus. Nat. Commun. 9, 1–9 (2018) DuncanM.C. ForbesJ.C. NguyenY. ShullL.M. GilletteR.K. LazinskiD.W. AliA. ShanksR.M. KadouriD.E. CamilliA. Vibrio cholerae motility exerts drag force to impede attack by the bacterial predator Bdellovibrio bacteriovorus Nat. Commun. 9 1 9 2018 10.1038/s41467-018-07245-3623212930420597 Search in Google Scholar

18 Duran N., Justo G.Z., Ferreira C.V., Melo P.S., Cordi L., Martins D.: Violacein: properties and biological activities. Biotechnol. Appl. Biochem. 48(Pt 3), 127–133 (2007) DuranN. JustoG.Z. FerreiraC.V. MeloP.S. CordiL. MartinsD. Violacein: properties and biological activities Biotechnol. Appl. Biochem. 48 Pt 3 127 133 2007 10.1042/BA2007011517927569 Search in Google Scholar

19 Dwidar M., Leung B.M., Yaguchi T., Takayama S., Mitchell R.J.: Patterning bacterial communities on epithelial cells. PLoS One, 8, e67165 (2013) DwidarM. LeungB.M. YaguchiT. TakayamaS. MitchellR.J. Patterning bacterial communities on epithelial cells PLoS One 8 e67165 2013 10.1371/journal.pone.0067165368176223785519 Search in Google Scholar

20 Dwidar M., Monnappa A.K., Mitchell R.J.: The dual probiotic and antibiotic nature of Bdellovibrio bacteriovorus. BMB Rep. 45(2), 71–78 (2012) DwidarM. MonnappaA.K. MitchellR.J. The dual probiotic and antibiotic nature of Bdellovibrio bacteriovorus BMB Rep. 45 2 71 78 2012 10.5483/BMBRep.2012.45.2.7122360883 Search in Google Scholar

21 Dwidar M., Nam D., Mitchell R.J.: Indole negatively impacts predation by Bdellovibrio bacteriovorus and its release from the bdelloplast. Environ. Microbiol. 17, 1009–1022 (2015) DwidarM. NamD. MitchellR.J. Indole negatively impacts predation by Bdellovibrio bacteriovorus and its release from the bdelloplast Environ. Microbiol. 17 1009 1022 2015 10.1111/1462-2920.1246324673893 Search in Google Scholar

22 Evans K.J., Lambert C., Sockett R.E.: Predation by Bdellovibrio bacteriovorus HD100 requires type IV Pili. J. Bacteriol. 189(13), 4850–4859 (2007) EvansK.J. LambertC. SockettR.E. Predation by Bdellovibrio bacteriovorus HD100 requires type IV Pili J. Bacteriol. 189 13 4850 4859 2007 10.1128/JB.01942-06191345517416646 Search in Google Scholar

23 Fenton A.K., Kanna M., Woods R.D., Aizawa S-I., Sockett R.E.: Shadowing the actions of a predator: backlit fluorescent microscopy reveals synchronous nonbinary septation of predatory bdellovibrio inside prey and exit through discrete bdelloplast pores. J. Bacteriol. 192(24), 6329–6335 (2010) FentonA.K. KannaM. WoodsR.D. AizawaS-I. SockettR.E. Shadowing the actions of a predator: backlit fluorescent microscopy reveals synchronous nonbinary septation of predatory bdellovibrio inside prey and exit through discrete bdelloplast pores J. Bacteriol. 192 24 6329 6335 2010 10.1128/JB.00914-10300853020935099 Search in Google Scholar

24 Findlay J.S., Flick-Smith H.C., Keyser E., Cooper I.A., Williamson E.D., Oyston P.C.: Predatory bacteria can protect SKH-1 mice from a lethal plague challenge. Sci. Rep. 9, 1–10 (2019) FindlayJ.S. Flick-SmithH.C. KeyserE. CooperI.A. WilliamsonE.D. OystonP.C. Predatory bacteria can protect SKH-1 mice from a lethal plague challenge Sci. Rep. 9 1 10 2019 10.1038/s41598-019-43467-1651079131076594 Search in Google Scholar

25 Gupta S., Tang C., Tran M., Kadouri D.E.: Effect of predatory bacteria on human cell lines. PLoS One, 11, e0161242 (2016) GuptaS. TangC. TranM. KadouriD.E. Effect of predatory bacteria on human cell lines PLoS One 11 e0161242 2016 10.1371/journal.pone.0161242500699227579919 Search in Google Scholar

26 Harding C.J., Huwiler S.G., Somers H., Lambert C., Ray L.J., Till R., Taylor G., Moynihan P.J., Sockett R.E., Lovering A.L.: A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus. Nat. Commun. 11, 1–12 (2020) HardingC.J. HuwilerS.G. SomersH. LambertC. RayL.J. TillR. TaylorG. MoynihanP.J. SockettR.E. LoveringA.L. A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus Nat. Commun. 11 1 12 2020 10.1038/s41467-020-18139-8751192632968056 Search in Google Scholar

27 Hobley L., Fung R.K., Lambert C., Harris M.A., Dabhi J.M., King S.S., Basford S.M., Uchida K., Till R., Ahmad R.: Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in Bdellovibrio bacteriovorus. PLoS. Pathog. 8, e1002493 (2012) HobleyL. FungR.K. LambertC. HarrisM.A. DabhiJ.M. KingS.S. BasfordS.M. UchidaK. TillR. AhmadR. Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in Bdellovibrio bacteriovorus PLoS. Pathog. 8 e1002493 2012 10.1371/journal.ppat.1002493327106422319440 Search in Google Scholar

28 Hobley L., Summers J.K., Till R., Milner D.S., Atterbury R.J., Stroud A., Capeness M.J., Gray S., Leidenroth A., Lambert C.: Dual predation by bacteriophage and Bdellovibrio bacteriovorus can eradicate Escherichia coli prey in situations where single predation cannot. J. Bacteriol. 202, e00629–19 (2020) HobleyL. SummersJ.K. TillR. MilnerD.S. AtterburyR.J. StroudA. CapenessM.J. GrayS. LeidenrothA. LambertC. Dual predation by bacteriophage and Bdellovibrio bacteriovorus can eradicate Escherichia coli prey in situations where single predation cannot J. Bacteriol. 202 e00629 19 2020 10.1128/JB.00629-19704367231907203 Search in Google Scholar

29 Iebba V., Santangelo F., Totino V., Nicoletti M., Gagliardi A., De Biase R.V., Cucchiara S., Nencioni L., Conte M.P., Schippa S.: Higher prevalence and abundance of Bdellovibrio bacteriovorus in the human gut of healthy subjects. PloS One, 8, e61608 (2013) IebbaV. SantangeloF. TotinoV. NicolettiM. GagliardiA. De BiaseR.V. CucchiaraS. NencioniL. ConteM.P. SchippaS. Higher prevalence and abundance of Bdellovibrio bacteriovorus in the human gut of healthy subjects PloS One 8 e61608 2013 10.1371/journal.pone.0061608362879423613881 Search in Google Scholar

30 Im H., Choi S.Y., Son S., Mitchell R.J.: Combined application of bacterial predation and violacein to kill polymicrobial pathogenic communities. Sci. Rep. 7, 1–10 (2017) ImH. ChoiS.Y. SonS. MitchellR.J. Combined application of bacterial predation and violacein to kill polymicrobial pathogenic communities Sci. Rep. 7 1 10 2017 10.1038/s41598-017-14567-7566395929089523 Search in Google Scholar

31 Im H., Son S., Mitchell R.J., Ghim C-M.: Serum albumin and osmolality inhibit Bdellovibrio bacteriovorus predation in human serum. Sci. Rep. 7, 1–9 (2017) ImH. SonS. MitchellR.J. GhimC-M. Serum albumin and osmolality inhibit Bdellovibrio bacteriovorus predation in human serum Sci. Rep. 7 1 9 2017 10.1038/s41598-017-06272-2551747028725056 Search in Google Scholar

32 Johnke J., Fraune S., Bosch T.C., Hentschel U., Schulenburg H.: Bdellovibrio and like organisms are predictors of microbiome diversity in distinct host groups. Microb. Ecol. 79, 252–257 (2020) JohnkeJ. FrauneS. BoschT.C. HentschelU. SchulenburgH. Bdellovibrio and like organisms are predictors of microbiome diversity in distinct host groups Microb. Ecol. 79 252 257 2020 10.1007/s00248-019-01395-731187177 Search in Google Scholar

33 Kadouri D.E., To K., Shanks R.M., Doi Y.: Predatory bacteria: a potential ally against multidrug-resistant Gram-negative pathogens. PloS One, 8, e63397 (2013) KadouriD.E. ToK. ShanksR.M. DoiY. Predatory bacteria: a potential ally against multidrug-resistant Gram-negative pathogens PloS One 8 e63397 2013 10.1371/journal.pone.0063397364111823650563 Search in Google Scholar

34 Kuru E., Lambert C., Rittichier J., Till R., Ducret A., Derouaux A., Gray J., Biboy J., Vollmer W., VanNieuwenhze M, et al.: Fluorescent D-amino-acids reveal bi-cellular cell wall modifications important for Bdellovibrio bacteriovorus predation. Nat. Microbiol. 2(12), 1648–1657 (2017) KuruE. LambertC. RittichierJ. TillR. DucretA. DerouauxA. GrayJ. BiboyJ. VollmerW. VanNieuwenhzeM Fluorescent D-amino-acids reveal bi-cellular cell wall modifications important for Bdellovibrio bacteriovorus predation Nat. Microbiol. 2 12 1648 1657 2017 10.1038/s41564-017-0029-y570557928974693 Search in Google Scholar

35 Lambert C., Evans K.J., Till R., Hobley L., Capeness M., Rendulic S., Schuster S.C., Aizawa S-I., Sockett R.E.: Characterizing the flagellar filament and the role of motility in bacterial prey-penetration by Bdellovibrio bacteriovorus. Mol. Microbiol. 60(2), 274–286 (2006) LambertC. EvansK.J. TillR. HobleyL. CapenessM. RendulicS. SchusterS.C. AizawaS-I. SockettR.E. Characterizing the flagellar filament and the role of motility in bacterial prey-penetration by Bdellovibrio bacteriovorus Mol. Microbiol. 60 2 274 286 2006 10.1111/j.1365-2958.2006.05081.x145331116573680 Search in Google Scholar

36 Lambert C., Ivanov P., Sockett RE.: A transcriptional “Scream” early response of E. coli prey to predatory invasion by Bdellovibrio. Curr. Microbiol. 60, 419–427 (2010) LambertC. IvanovP. SockettRE. A transcriptional “Scream” early response of E. coli prey to predatory invasion by Bdellovibrio Curr. Microbiol. 60 419 427 2010 10.1007/s00284-009-9559-8285916620024656 Search in Google Scholar

37 Lambert C., Lerner T.R., Bui N.K., Somers H., Aizawa S-I., Liddell S., Clark A., Vollmer W., Lovering A.L., Sockett R.E, et al.: Interrupting peptidoglycan deacetylation during Bdellovibrio predator-prey interaction prevents ultimate destruction of prey wall, liberating bacterial-ghosts. Sci. Rep. 6, 26010 (2016) LambertC. LernerT.R. BuiN.K. SomersH. AizawaS-I. LiddellS. ClarkA. VollmerW. LoveringA.L. SockettR.E Interrupting peptidoglycan deacetylation during Bdellovibrio predator-prey interaction prevents ultimate destruction of prey wall, liberating bacterial-ghosts Sci. Rep. 6 26010 2016 10.1038/srep26010487650627211869 Search in Google Scholar

38 Lerner T.R., Lovering A.L., Bui N.K., Uchida K., Aizawa S-I., Vollmer W., Sockett R.E.: Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory bdellovibrio and increase population fitness. PLoS Pathog. 8(2), e1002524 (2012) LernerT.R. LoveringA.L. BuiN.K. UchidaK. AizawaS-I. VollmerW. SockettR.E. Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory bdellovibrio and increase population fitness PLoS Pathog. 8 2 e1002524 2012 10.1371/journal.ppat.1002524327656622346754 Search in Google Scholar

39 Lima I.F., Havt A., Lima A.A.: Update on molecular epidemiology of Shigella infection. Curr. Opin. Gastroenterol. 31, 30–37 (2015) LimaI.F. HavtA. LimaA.A. Update on molecular epidemiology of Shigella infection Curr. Opin. Gastroenterol. 31 30 37 2015 10.1097/MOG.000000000000013625394237 Search in Google Scholar

40 Linares-Otoya L., Linares-Otoya V., Armas-Mantilla L., Blanco-Olano C., Crüsemann M., Ganoza-Yupanqui M.L., Campos-Florian J., König G.M., Schäberle T.F.: Diversity and antimicrobial potential of predatory bacteria from the Peruvian Coastline. Mar. Drugs, 15, 308 (2017) Linares-OtoyaL. Linares-OtoyaV. Armas-MantillaL. Blanco-OlanoC. CrüsemannM. Ganoza-YupanquiM.L. Campos-FlorianJ. KönigG.M. SchäberleT.F. Diversity and antimicrobial potential of predatory bacteria from the Peruvian Coastline Mar. Drugs 15 308 2017 10.3390/md15100308566641629023396 Search in Google Scholar

41 Mahmoud K.K., Koval S.F.: Characterization of type IV pili in the life cycle of the predator bacterium Bdellovibrio. Microbiology, 156(Pt 4), 1040–1051 (2010) MahmoudK.K. KovalS.F. Characterization of type IV pili in the life cycle of the predator bacterium Bdellovibrio Microbiology 156 Pt 4 1040 1051 2010 10.1099/mic.0.036137-020056705 Search in Google Scholar

42 Makowski Ł., Trojanowski D., Till R., Lambert C., Lowry R., Sockett R.E., Zakrzewska-Czerwinska J.: Dynamics of chromosome replication and its relationship to predatory attack life-styles in Bdellovibrio bacteriovorus. Appl. Environ. Microbiol. 85(14), e00730–19 (2019) MakowskiŁ. TrojanowskiD. TillR. LambertC. LowryR. SockettR.E. Zakrzewska-CzerwinskaJ. Dynamics of chromosome replication and its relationship to predatory attack life-styles in Bdellovibrio bacteriovorus Appl. Environ. Microbiol. 85 14 e00730 19 2019 10.1128/AEM.00730-19 Search in Google Scholar

43 Marine E., Milner D.S., Lambert C., Sockett R.E., Pos K.M.: A novel method to determine antibiotic sensitivity in Bdellovibrio bacteriovorus reveals a DHFR-dependent natural trimethoprim resistance. Sci. Rep. 10, 1–10 (2020) MarineE. MilnerD.S. LambertC. SockettR.E. PosK.M. A novel method to determine antibiotic sensitivity in Bdellovibrio bacteriovorus reveals a DHFR-dependent natural trimethoprim resistance Sci. Rep. 10 1 10 2020 10.1038/s41598-020-62014-x709339632210253 Search in Google Scholar

44 Martínez V., Herencias C., Jurkevitch E., Prieto M.A.: Engineering a predatory bacterium as a proficient killer agent for intracellular bio-products recovery: the case of the polyhydroxyalkanoates. Sci. Rep. 6, 1–12 (2016) MartínezV. HerenciasC. JurkevitchE. PrietoM.A. Engineering a predatory bacterium as a proficient killer agent for intracellular bio-products recovery: the case of the polyhydroxyalkanoates Sci. Rep. 6 1 12 2016 10.1038/srep24381483455427087466 Search in Google Scholar

45 Monnappa A.K., Bari W., Choi S.Y., Mitchell R.J.: Investigating the responses of human epithelial cells to predatory bacteria. Sci. Rep. 6, 1–14. (2016) MonnappaA.K. BariW. ChoiS.Y. MitchellR.J. Investigating the responses of human epithelial cells to predatory bacteria Sci. Rep. 6 1 14 2016 10.1038/srep33485502416427629536 Search in Google Scholar

46 Monnappa A.K., Dwidar M., Mitchell R.J.: Application of bacterial predation to mitigate recombinant bacterial populations and their DNA. Soil Biol. Biochem. 57, 427–435 (2013) MonnappaA.K. DwidarM. MitchellR.J. Application of bacterial predation to mitigate recombinant bacterial populations and their DNA Soil Biol. Biochem. 57 427 435 2013 10.1016/j.soilbio.2012.09.010 Search in Google Scholar

47 Mun W., Kwon H., Im H., Choi S.Y., Monnappa A.K., Mitchell R.J.: Cyanide production by Chromobacterium piscinae shields it from Bdellovibrio bacteriovorus HD100 predation. mBio. 8(6), 1–12 (2017) MunW. KwonH. ImH. ChoiS.Y. MonnappaA.K. MitchellR.J. Cyanide production by Chromobacterium piscinae shields it from Bdellovibrio bacteriovorus HD100 predation mBio. 8 6 1 12 2017 10.1128/mBio.01370-17573690729259082 Search in Google Scholar

48 Nair R.R., Vasse M., Wielgoss S., Sun L., Yuen-Tsu N.Y., Velicer G.J.: Bacterial predator-prey coevolution accelerates genome evolution and selects on virulence-associated prey defences. Nat. Commun. 10, 1–10 (2019) NairR.R. VasseM. WielgossS. SunL. Yuen-TsuN.Y. VelicerG.J. Bacterial predator-prey coevolution accelerates genome evolution and selects on virulence-associated prey defences Nat. Commun. 10 1 10 2019 10.1038/s41467-019-12140-6675441831541093 Search in Google Scholar

49 Odooli S., Roghanian R., Ghasemi Y., Mohkam M., Emtiazi G.: Predatory and biocontrol potency of Bdellovibrio bacteriovorus toward phytopathogenic strains of Pantoea sp. and Xanthomonas campestris in the presence of exo-biopolymers: in vitro and in vivo assessments. Int. Microbiol. 1, 1–15 (2021) OdooliS. RoghanianR. GhasemiY. MohkamM. EmtiaziG. Predatory and biocontrol potency of Bdellovibrio bacteriovorus toward phytopathogenic strains of Pantoea sp. and Xanthomonas campestris in the presence of exo-biopolymers: in vitro and in vivo assessments Int. Microbiol. 1 1 15 2021 10.1007/s10123-021-00177-x33956240 Search in Google Scholar

50 Olanya O., Niemira B., Cassidy J., Boyd G., Uknalis J.: Pathogen reduction by predatory bacteria and survival of Bdellovibrio bacteriovorus and Escherichia coli on produce and buffer treated with low-dose gamma radiation. LWT, 130, 109630 (2020) OlanyaO. NiemiraB. CassidyJ. BoydG. UknalisJ. Pathogen reduction by predatory bacteria and survival of Bdellovibrio bacteriovorus and Escherichia coli on produce and buffer treated with low-dose gamma radiation LWT 130 109630 2020 10.1016/j.lwt.2020.109630 Search in Google Scholar

51 Ottaviani D., Pieralisi S., Angelico G., Mosca F., Tiscar P.G., Rocchegiani E., Scuota S., Petruzzelli A., Fisichella S., Blasi G.: Bdellovibrio bacteriovorus to control Escherichia coli on meat matrices. Int. J. Food Sci. 55, 988–994 (2020) OttavianiD. PieralisiS. AngelicoG. MoscaF. TiscarP.G. RocchegianiE. ScuotaS. PetruzzelliA. FisichellaS. BlasiG. Bdellovibrio bacteriovorus to control Escherichia coli on meat matrices Int. J. Food Sci. 55 988 994 2020 10.1111/ijfs.14355 Search in Google Scholar

52 Özkan M., Yılmaz H., Çelik M.A., Şengezer Ç., Erhan E., Keskinler B.: Application of Bdellovibrio bacteriovorus for reducing fouling of membranes used for wastewater treatment. Turk Biyokim. Derg. 43, 296–305 (2018) ÖzkanM. YılmazH. ÇelikM.A. ŞengezerÇ. ErhanE. KeskinlerB. Application of Bdellovibrio bacteriovorus for reducing fouling of membranes used for wastewater treatment Turk Biyokim. Derg. 43 296 305 2018 10.1515/tjb-2016-0302 Search in Google Scholar

53 Pasternak Z., Njagi M., Shani Y., Chanyi R., Rotem O., Lurie-Weinberger M.N., Koval S., Pietrokovski S., Gophna U., Jurkevitch E.: In and out: an analysis of epibiotic vs periplasmic bacterial predators. ISME J. 8, 625–635 (2014) PasternakZ. NjagiM. ShaniY. ChanyiR. RotemO. Lurie-WeinbergerM.N. KovalS. PietrokovskiS. GophnaU. JurkevitchE. In and out: an analysis of epibiotic vs periplasmic bacterial predators ISME J. 8 625 635 2014 10.1038/ismej.2013.164393030824088628 Search in Google Scholar

54 Patini R., Cattani P., Marchetti S., Isola G., Quaranta G., Gallenzi P.: Evaluation of predation capability of periodontopathogens bacteria by Bdellovibrio Bacteriovorus HD100. an in vitro study. Materials, 12(12), 2008 (2019) PatiniR. CattaniP. MarchettiS. IsolaG. QuarantaG. GallenziP. Evaluation of predation capability of periodontopathogens bacteria by Bdellovibrio Bacteriovorus HD100. an in vitro study Materials 12 12 2008 2019 10.3390/ma12122008663074931234568 Search in Google Scholar

55 Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A, et al.: A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective. Science, 303(5658), 689–692 (2004) RendulicS. JagtapP. RosinusA. EppingerM. BaarC. LanzC. KellerH. LambertC. EvansK.J. GoesmannA A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective Science 303 5658 689 692 2004 10.1126/science.109302714752164 Search in Google Scholar

56 Romanowski E.G., Gupta S., Pericleous A., Kadouri D.E., Shanks R.M.: Clearance of Gram-Negative Bacterial Pathogens from the Ocular Surface by Predatory Bacteria. Antibiotics, 10, 810 (2021) RomanowskiE.G. GuptaS. PericleousA. KadouriD.E. ShanksR.M. Clearance of Gram-Negative Bacterial Pathogens from the Ocular Surface by Predatory Bacteria Antibiotics 10 810 2021 10.3390/antibiotics10070810830075234356731 Search in Google Scholar

57 Romanowski E.G., Stella N.A., Brothers K.M., Yates K.A., Funderburgh M.L., Funderburgh J.L., Gupta S., Dharani S., Kadouri D.E., Shanks R.M.: Predatory bacteria are nontoxic to the rabbit ocular surface. Sci. Rep. 6, 1–9 (2016) RomanowskiE.G. StellaN.A. BrothersK.M. YatesK.A. FunderburghM.L. FunderburghJ.L. GuptaS. DharaniS. KadouriD.E. ShanksR.M. Predatory bacteria are nontoxic to the rabbit ocular surface Sci. Rep. 6 1 9 2016 10.1038/srep30987498581527527833 Search in Google Scholar

58 Ruban-Osmiałowska B., Jakimowicz D., Smulczyk-Krawczyszyn A., Chater K.F., Zakrzewska-Czerwinska J.: Replisome localization in vegetative and aerial hyphae of Streptomyces coelicolor. J. Bacteriol. 188(20), 7311–7316 (2006) Ruban-OsmiałowskaB. JakimowiczD. Smulczyk-KrawczyszynA. ChaterK.F. Zakrzewska-CzerwinskaJ. Replisome localization in vegetative and aerial hyphae of Streptomyces coelicolor J. Bacteriol. 188 20 7311 7316 2006 10.1128/JB.00940-06163623217015671 Search in Google Scholar

59 Russo R., Kolesnikova I., Kim T., Gupta S., Pericleous A., Kadouri D.E., Connell N.D.: Susceptibility of virulent Yersinia pestis bacteria to predator bacteria in the lungs of mice. Microorganisms, 7, 2 (2019) RussoR. KolesnikovaI. KimT. GuptaS. PericleousA. KadouriD.E. ConnellN.D. Susceptibility of virulent Yersinia pestis bacteria to predator bacteria in the lungs of mice Microorganisms 7 2 2019 10.3390/microorganisms7010002635195430577606 Search in Google Scholar

60 Sathyamoorthy R., Kushmaro Y., Rotem O., Matan O., Kadouri D.E., Huppert A., Jurkevitch E.: To hunt or to rest: prey depletion induces a novel starvation survival strategy in bacterial predators. ISME. J. 15, 109–123 (2021) SathyamoorthyR. KushmaroY. RotemO. MatanO. KadouriD.E. HuppertA. JurkevitchE. To hunt or to rest: prey depletion induces a novel starvation survival strategy in bacterial predators ISME. J. 15 109 123 2021 10.1038/s41396-020-00764-2785254432884113 Search in Google Scholar

61 Saxon E.B., Jackson R.W., Bhumbra S., Smith T., Sockett R.E.: Bdellovibrio bacteriovorus HD100 guards against Pseudomonas tolaasii brown-blotch lesions on the surface of post-harvest Agaricus bisporus supermarket mushrooms. BMC Microbiol. 14, 1–12 (2014) SaxonE.B. JacksonR.W. BhumbraS. SmithT. SockettR.E. Bdellovibrio bacteriovorus HD100 guards against Pseudomonas tolaasii brown-blotch lesions on the surface of post-harvest Agaricus bisporus supermarket mushrooms BMC Microbiol. 14 1 12 2014 10.1186/1471-2180-14-163407755524946855 Search in Google Scholar

62 Schoeffield A.J., Williams H.N., Turng B., Fackler W.A.: A comparison of the survival of intraperiplasmic and attack phase bdellovibrios with reduced oxygen. Microb. Ecol. 32(1), 35–46 (1996) SchoeffieldA.J. WilliamsH.N. TurngB. FacklerW.A. A comparison of the survival of intraperiplasmic and attack phase bdellovibrios with reduced oxygen Microb. Ecol. 32 1 35 46 1996 10.1007/BF001701058661540 Search in Google Scholar

63 Seidler R.J., Starr M.P.: Factors affecting the intracellular parasitic growth of Bdellovibrio bacteriovorus developing within Escherichia coli. J. Bacteriol. 97(2), 912–923 (1969) SeidlerR.J. StarrM.P. Factors affecting the intracellular parasitic growth of Bdellovibrio bacteriovorus developing within Escherichia coli J. Bacteriol. 97 2 912 923 1969 10.1128/jb.97.2.912-923.19692497774886299 Search in Google Scholar

64 Shanks R.M., Davra V.R., Romanowski E.G., Brothers K.M., Stella N.A., Godboley D., Kadouri D.E.: An eye to a kill: using predatory bacteria to control Gram-negative pathogens associated with ocular infections. PLoS One, 8, e66723 (2013) ShanksR.M. DavraV.R. RomanowskiE.G. BrothersK.M. StellaN.A. GodboleyD. KadouriD.E. An eye to a kill: using predatory bacteria to control Gram-negative pathogens associated with ocular infections PLoS One 8 e66723 2013 10.1371/journal.pone.0066723368893023824756 Search in Google Scholar

65 Shatzkes K., Chae R., Tang C., Ramirez G.C., Mukherjee S., Tsenova L., Connell N.D., Kadouri D.E.: Examining the safety of respiratory and intravenous inoculation of Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus in a mouse model. Sci. Rep. 5, 1–12 (2015) ShatzkesK. ChaeR. TangC. RamirezG.C. MukherjeeS. TsenovaL. ConnellN.D. KadouriD.E. Examining the safety of respiratory and intravenous inoculation of Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus in a mouse model Sci. Rep. 5 1 12 2015 10.1038/srep12899452822826250699 Search in Google Scholar

66 Shatzkes K., Singleton E., Tang C., Zuena M., Shukla S., Gupta S., Dharani S., Rinaggio J., Kadouri D.E., Connell N.D.: Examining the efficacy of intravenous administration of predatory bacteria in rats. Sci. Rep. 7, 1–11 (2017) ShatzkesK. SingletonE. TangC. ZuenaM. ShuklaS. GuptaS. DharaniS. RinaggioJ. KadouriD.E. ConnellN.D. Examining the efficacy of intravenous administration of predatory bacteria in rats Sci. Rep. 7 1 11 2017 10.1038/s41598-017-02041-3543185628500337 Search in Google Scholar

67 Starr M.P., Baigent N.L.: Parasitic interaction of Bdellovibrio bacteriovorus with other bacteria. J. Bacteriol. 91(5), 2006–2017 (1966) StarrM.P. BaigentN.L. Parasitic interaction of Bdellovibrio bacteriovorus with other bacteria J. Bacteriol. 91 5 2006 2017 1966 10.1128/jb.91.5.2006-2017.19663161585327913 Search in Google Scholar

68 Stolp H., Starr M.P.: Bdellovibrio bacteriovorus gen. et sp.n., a predatory, ectoparasitic, and bacteriolytic microorganism. Antonie Van Leeuwenhoek, 29(1), 217–248 (1963) StolpH. StarrM.P. Bdellovibrio bacteriovorus gen. et sp.n., a predatory, ectoparasitic, and bacteriolytic microorganism Antonie Van Leeuwenhoek 29 1 217 248 1963 10.1007/BF0204606414068454 Search in Google Scholar

69 Thomashow M.F., Cotter T.W.: Bdellovibrio host dependence: the search for signal molecules and genes that regulate the intraperiplasmic growth cycle. J. Bacteriol. 174(18), 5767–5771 (1992) ThomashowM.F. CotterT.W. Bdellovibrio host dependence: the search for signal molecules and genes that regulate the intraperiplasmic growth cycle J. Bacteriol. 174 18 5767 5771 1992 10.1128/jb.174.18.5767-5771.19922071011522057 Search in Google Scholar

70 Thomashow M.F., Rittenberg S.C.: Intraperiplasmic growth of Bdellovibrio bacteriovorus 109J: solubilization of Escherichia coli peptidoglycan. J. Bacteriol. 135(3), 998–1007 (1978) ThomashowM.F. RittenbergS.C. Intraperiplasmic growth of Bdellovibrio bacteriovorus 109J: solubilization of Escherichia coli peptidoglycan J. Bacteriol. 135 3 998 1007 1978 10.1128/jb.135.3.998-1007.1978222476357428 Search in Google Scholar

71 Tudor J.J., McCann M.P., Acrich I.A.: A new model for the penetration of prey cells by bdellovibrios. J. Bacteriol. 172(5), 2421–2426 (1990) TudorJ.J. McCannM.P. AcrichI.A. A new model for the penetration of prey cells by bdellovibrios J. Bacteriol. 172 5 2421 2426 1990 10.1128/jb.172.5.2421-2426.19902088782185219 Search in Google Scholar

72 Tyc O., Song C., Dickschat J.S., Vos M., Garbeva P.: The ecological role of volatile and soluble secondary metabolites produced by soil bacteria. Trends Microbiol. 25(4), 280–292 (2017) TycO. SongC. DickschatJ.S. VosM. GarbevaP. The ecological role of volatile and soluble secondary metabolites produced by soil bacteria Trends Microbiol. 25 4 280 292 2017 10.1016/j.tim.2016.12.00228038926 Search in Google Scholar

73 Waso M., Khan S., Singh A., McMichael S., Ahmed W., Fernandez-Ibanez P., Byrne J., Khan W.: Predatory bacteria in combination with solar disinfection and solar photocatalysis for the treatment of rainwater. Water Res. 169, 115281 (2020) WasoM. KhanS. SinghA. McMichaelS. AhmedW. Fernandez-IbanezP. ByrneJ. KhanW. Predatory bacteria in combination with solar disinfection and solar photocatalysis for the treatment of rainwater Water Res. 169 115281 2020 10.1016/j.watres.2019.11528131733621 Search in Google Scholar

74 Wen C., Xue M., Liang H., Zhou S.: Evaluating the potential of marine Bacteriovorax sp. DA5 as a biocontrol agent against vibriosis in Litopenaeus vannamei larvae. Vet. Microbiol. 173, 84–91 (2014) WenC. XueM. LiangH. ZhouS. Evaluating the potential of marine Bacteriovorax sp. DA5 as a biocontrol agent against vibriosis in Litopenaeus vannamei larvae Vet. Microbiol. 173 84 91 2014 10.1016/j.vetmic.2014.07.02225139659 Search in Google Scholar

75 Willis A.R., Moore C., Mazon-Moya M., Krokowski S., Lambert C., Till R., Mostowy S., Sockett R.E.: Injections of predatory bacteria work alongside host immune cells to treat Shigella infection in zebrafish larvae. Curr. Biol. 26, 3343–3351 (2016) WillisA.R. MooreC. Mazon-MoyaM. KrokowskiS. LambertC. TillR. MostowyS. SockettR.E. Injections of predatory bacteria work alongside host immune cells to treat Shigella infection in zebrafish larvae Curr. Biol. 26 3343 3351 2016 10.1016/j.cub.2016.09.067519602427889262 Search in Google Scholar

76 Wolanski M., Wali R., Tilley E., Jakimowicz D., Zakrzewska-Czerwinska J., Herron P.: Replisome trafficking in growing vegetative hyphae of Streptomyces coelicolor A3(2). J. Bacteriol. 193(5), 1273–1275 (2011) WolanskiM. WaliR. TilleyE. JakimowiczD. Zakrzewska-CzerwinskaJ. HerronP. Replisome trafficking in growing vegetative hyphae of Streptomyces coelicolor A3(2) J. Bacteriol. 193 5 1273 1275 2011 10.1128/JB.01326-10306758621193604 Search in Google Scholar

77 Youdkes D., Helman Y., Burdman S., Matan O., Jurkevitch E.: Potential control of potato soft rot disease by the obligate predators bdellovibrio and like organisms. Appl. Environ. Microbiol. 86(6), 1–13 (2020) YoudkesD. HelmanY. BurdmanS. MatanO. JurkevitchE. Potential control of potato soft rot disease by the obligate predators bdellovibrio and like organisms Appl. Environ. Microbiol. 86 6 1 13 2020 10.1128/AEM.02543-19705409531953332 Search in Google Scholar