<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Polycystic Ovarian Syndrome (PCOS) is a disease that is characterized by an increased Gonadotropin-Releasing-Hormone (GnRH) pulsatile frequency, causing an altered LH/FSH ratio. More precisely an increased Luteinizing Hormone (LH) secretion compared to a decreased Follicle-Stimulating Hormone (FSH) secretion leads to the development of hyperandrogenism and to a low-level concentration of estrogens and therefore decreased negative estrogenic feedback in the control axis. The purpose of this review is to connect the physiological Hypothalamic-Pituitary-Ovarian (HPO) axis with said pathology and the ensuring discussion about the possible mechanisms of pathogenesis and guidelines for relieving associated symptoms.</p>
</abstract>

Polycystic Ovarian Syndrome (PCOS) is a disease that is characterized by an increased Gonadotropin-Releasing-Hormone (GnRH) pulsatile frequency, causing an altered LH/FSH ratio. More precisely an increased Luteinizing Hormone (LH) secretion compared to a decreased Follicle-Stimulating Hormone (FSH) secretion leads to the development of hyperandrogenism and to a low-level concentration of estrogens and therefore decreased negative estrogenic feedback in the control axis. The purpose of this review is to connect the physiological Hypothalamic-Pituitary-Ovarian (HPO) axis with said pathology and the ensuring discussion about the possible mechanisms of pathogenesis and guidelines for relieving associated symptoms.

Hormone Imbalance in Polycystic Ovarian Syndrome

George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureş

Acta Biologica Marisiensis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Hormone Imbalance in Polycystic Ovarian Syndrome"}

Polycystic Ovarian Syndrome (PCOS) is a disease that is characterized by an increased Gonadotropin-Releasing-Hormone (GnRH) pulsatile frequency, causing an...

Hormone Imbalance in Polycystic Ovarian Syndrome

Data publikacji: 23 cze 2023

Zakres stron: 10 - 20

Otrzymano: 08 lut 2023

Przyjęty: 19 mar 2023

DOI: https://doi.org/10.2478/abmj-2023-0002

Słowa kluczowe
Polycystic Ovarian Syndrome, hyperandrogenism, hyperestrogenism, infertility, hirsutism

© 2023 Ivan Bergo et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Hormone Imbalance in Polycystic Ovarian Syndrome

Data publikacji: 23 cze 2023

Zakres stron: 10 - 20

Otrzymano: 08 lut 2023

Przyjęty: 19 mar 2023

DOI: https://doi.org/10.2478/abmj-2023-0002

Słowa kluczowePolycystic Ovarian Syndrome, hyperandrogenism, hyperestrogenism, infertility, hirsutism

© 2023 Ivan Bergo et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Słowa kluczowe
Polycystic Ovarian Syndrome, hyperandrogenism, hyperestrogenism, infertility, hirsutism