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Peguero–Lo Presti criteria modified by body surface area for the electrocardiographic diagnosis of left ventricular hypertrophy in Thai patients

Wongsakorn Luangphiphat
Wongsakorn Luangphiphat
, 
Atthaphon Phaisitkriengkrai
Atthaphon Phaisitkriengkrai
, 
Ratikorn Methavigul
Ratikorn Methavigul
 oraz 
Komsing Methavigul
Komsing Methavigul
   | 30 kwi 2021
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Article Category: Brief communication (original)
Data publikacji: 30 kwi 2021
Zakres stron: 101 - 107
DOI: https://doi.org/10.2478/abm-2021-0012
Słowa kluczowe
© 2021 Wongsakorn Luangphiphat et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Figure 1

Flow chart for sampling of patients whose data were included in the study. Randomized sampling was web-based (https://www.sealedenvelope.com/simple-randomiser/v1/lists). AVB, atrioventricular block; CXR, chest X-ray imaging; CRBB, complete right bundle branch block; CLBB, complete left bundle branch block; ECG, electrocardiography; HCM, hypertrophic cardiomyopathy; LV, left ventricular; LVH, left ventricular hypertropy; LAFB, left anterior fascicular block; LPFB, left posterior fascicular block; MI, myocardial infarction; RV, right ventricular; RVH, right ventricular hypertrophy.
Flow chart for sampling of patients whose data were included in the study. Randomized sampling was web-based (https://www.sealedenvelope.com/simple-randomiser/v1/lists). AVB, atrioventricular block; CXR, chest X-ray imaging; CRBB, complete right bundle branch block; CLBB, complete left bundle branch block; ECG, electrocardiography; HCM, hypertrophic cardiomyopathy; LV, left ventricular; LVH, left ventricular hypertropy; LAFB, left anterior fascicular block; LPFB, left posterior fascicular block; MI, myocardial infarction; RV, right ventricular; RVH, right ventricular hypertrophy.

Figure 2

Sensitivity and specificity of the ECG criteria against the echocardiographic LVH. Dark gray bars indicate sensitivity and open bars indicate specificity. Error bars indicate 95% confidence intervals. ECG, electrocardiographic; LVH, left ventricular hypertrophy.
Sensitivity and specificity of the ECG criteria against the echocardiographic LVH. Dark gray bars indicate sensitivity and open bars indicate specificity. Error bars indicate 95% confidence intervals. ECG, electrocardiographic; LVH, left ventricular hypertrophy.

Figure 3

AUC of the ECG criteria against the echocardiographic LVH. Dashed blue line indicates Peguero–Lo Presti criteria (AUC 0.67), solid purple line indicates Peguero–Lo Presti criteria modified by BSA (AUC 0.67), short-dashed green line indicates Sokolow–Lyon voltage criteria (AUC 0.59), and long-dashed orange line indicates Cornell voltage criteria (AUC 0.71). The teal line is for reference. AUC, area under a receiver-operating characteristic curve; BSA, body surface area; ECG, electrocardiographic; LVH, left ventricular hypertrophy.
AUC of the ECG criteria against the echocardiographic LVH. Dashed blue line indicates Peguero–Lo Presti criteria (AUC 0.67), solid purple line indicates Peguero–Lo Presti criteria modified by BSA (AUC 0.67), short-dashed green line indicates Sokolow–Lyon voltage criteria (AUC 0.59), and long-dashed orange line indicates Cornell voltage criteria (AUC 0.71). The teal line is for reference. AUC, area under a receiver-operating characteristic curve; BSA, body surface area; ECG, electrocardiographic; LVH, left ventricular hypertrophy.

Baseline characteristics of the patients with available echocardiography and with and without LVH

Demographic Total n = 317 n (%) or mean ± SD LVH n = 164 n (%) or mean ± SD No LVH n = 153 n (%) or mean ± SD P
Age (years) 57.2 ± 16.5 63.5 ± 13.2 50.4 ± 17.1 <0.01
Male sex 134 (42.3%) 59 (36%) 75 (49%) 0.02
Body weight (kg) 64.6 ± 15.2 64.6 ± 15.9 64.5 ± 14.5 0.98
Body surface area (m2) 1.7 ± 0.2 1.7 ± 0.2 1.7 ± 0.2 0.37
Medical history
Hypertension 151 (48) 97 (59) 54 (35) <0.01
Diabetes mellitus 53 (17) 36 (22) 17 (11) 0.01
Dyslipidemia 158 (50) 101 (62) 57 (37) <0.01
COPD 16 (5) 11 (7) 5 (3) 0.16
Heart failure 58 (18) 42 (26) 16 (11) <0.01
Atrial fibrillation 57 (18) 29 (18) 28 (18) 0.89
Peripheral arterial disease 3 (1) 1 (1) 2 (1) 0.52
History of myocardial infarction 20 (6) 12 (7) 8 (5) 0.45
Valvular heart disease 76 (24) 46 (28) 30 (20) 0.08
  • Aortic stenosis 8 (3) 7 (4) 1 (1) 0.04
  • Aortic regurgitation 13 (4) 12 (7) 1 (1) <0.01
  • Mitral regurgitation 15 (5) 13 (8) 2 (1) 0.01
History of stroke or TIA 12 (4) 8 (5) 4 (3) 0.29
Chronic kidney disease 10 (3) 7 (4) 3 (2) 0.24
Prior PCI 22 (7) 15 (9) 7 (5) 0.11
Prior CABG 8 (3) 5 (3) 3 (2) 0.54
Echocardiographic parameters
LVEF (%) 66.5 ± 7.3 66.1 ± 7.5 67.1 ± 7.1 0.18
LV mass index (g/m2) 113.0 ± 41.1 141.6 ± 35.9 82.3 ± 17.3 <0.01
Relative wall thickness 0.6 ± 2.3 0.8 ± 3.2 0.5 ± 0.1 0.24
Medications
  • Beta-blockers 95 (30) 56 (34) 39 (26) 0.09
  • ACEIs/ARBs 48 (15) 32 (20) 16 (11) 0.03
  • Calcium channel blockers 71 (22) 48 (29) 23 (15) <0.01
  • Diuretics 44 (14) 33 (20) 11 (7) <0.01
SBP (mmHg) 130.1 ± 20.1 135.2 ± 20.8 124.6 ± 17.7 <0.01
DBP (mmHg) 77.1 ± 13.3 78.1 ± 13.46 76.1 ± 13.0 0.20
Creatinine (mg/dL) 1.0 ± 0.7 1.1 ± 1.0 0.9 ± 0.3 0.23
eGFR (mL/min/m2) 83.4 ± 24.4 74.5 ± 24.2 91.4 ± 21.9 <0.01

McNemar test and AUC for the electrocardiographic criteria against the echocardiographic LVH

Test Sensitivity (%) Specificity (%) PPV (%) NPV (%) AUC P AUC *P McNemar
Peguero–Lo Presti LVH 29.9 (23.0–37.5) 90.9 (85.1–94.9) 77.8 (65.5–87.3) 54.7 (48.4–61.0) 0.67 (0.61–0.73) <0.01 <0.01
Modified Peguero–Lo Presti LVH 50.6 (42.7–58.5) 88.2 (82.0–92.9) 82.2 (73.3–89.1) 62.5 (55.7–69.0) 0.67 (0.61–0.73) <0.01 <0.01
Sokolow–Lyon LVH 18.3 (12.7–25.1) 88.9 (82.8–93.4) 63.8 (48.5–77.3) 50.4 (44.2–56.5) 0.59 (0.53–0.66) 0.06 <0.01
Cornell LVH 14.0 (9.1–20.3) 98.0 (94.4–99.6) 88.5 (69.8–97.6) 51.5 (45.6–57.4) 0.71 (0.65–0.76) 0.08 <0.01
eISSN:
1875-855X
Język:
Angielski
Częstotliwość wydawania:
6 razy w roku
Dziedziny czasopisma:
Medicine, Assistive Professions, Nursing, Basic Medical Science, other, Clinical Medicine
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