Age (years) |
57.2 ± 16.5 |
63.5 ± 13.2 |
50.4 ± 17.1 |
<0.01 |
Male sex |
134 (42.3%) |
59 (36%) |
75 (49%) |
0.02 |
Body weight (kg) |
64.6 ± 15.2 |
64.6 ± 15.9 |
64.5 ± 14.5 |
0.98 |
Body surface area (m2) |
1.7 ± 0.2 |
1.7 ± 0.2 |
1.7 ± 0.2 |
0.37 |
Medical history |
Hypertension |
151 (48) |
97 (59) |
54 (35) |
<0.01 |
Diabetes mellitus |
53 (17) |
36 (22) |
17 (11) |
0.01 |
Dyslipidemia |
158 (50) |
101 (62) |
57 (37) |
<0.01 |
COPD |
16 (5) |
11 (7) |
5 (3) |
0.16 |
Heart failure |
58 (18) |
42 (26) |
16 (11) |
<0.01 |
Atrial fibrillation |
57 (18) |
29 (18) |
28 (18) |
0.89 |
Peripheral arterial disease |
3 (1) |
1 (1) |
2 (1) |
0.52 |
History of myocardial infarction |
20 (6) |
12 (7) |
8 (5) |
0.45 |
Valvular heart disease |
76 (24) |
46 (28) |
30 (20) |
0.08 |
• Aortic stenosis |
8 (3) |
7 (4) |
1 (1) |
0.04 |
• Aortic regurgitation |
13 (4) |
12 (7) |
1 (1) |
<0.01 |
• Mitral regurgitation |
15 (5) |
13 (8) |
2 (1) |
0.01 |
History of stroke or TIA |
12 (4) |
8 (5) |
4 (3) |
0.29 |
Chronic kidney disease |
10 (3) |
7 (4) |
3 (2) |
0.24 |
Prior PCI |
22 (7) |
15 (9) |
7 (5) |
0.11 |
Prior CABG |
8 (3) |
5 (3) |
3 (2) |
0.54 |
Echocardiographic parameters |
LVEF (%) |
66.5 ± 7.3 |
66.1 ± 7.5 |
67.1 ± 7.1 |
0.18 |
LV mass index (g/m2) |
113.0 ± 41.1 |
141.6 ± 35.9 |
82.3 ± 17.3 |
<0.01 |
Relative wall thickness |
0.6 ± 2.3 |
0.8 ± 3.2 |
0.5 ± 0.1 |
0.24 |
Medications |
|
|
|
|
• Beta-blockers |
95 (30) |
56 (34) |
39 (26) |
0.09 |
• ACEIs/ARBs |
48 (15) |
32 (20) |
16 (11) |
0.03 |
• Calcium channel blockers |
71 (22) |
48 (29) |
23 (15) |
<0.01 |
• Diuretics |
44 (14) |
33 (20) |
11 (7) |
<0.01 |
SBP (mmHg) |
130.1 ± 20.1 |
135.2 ± 20.8 |
124.6 ± 17.7 |
<0.01 |
DBP (mmHg) |
77.1 ± 13.3 |
78.1 ± 13.46 |
76.1 ± 13.0 |
0.20 |
Creatinine (mg/dL) |
1.0 ± 0.7 |
1.1 ± 1.0 |
0.9 ± 0.3 |
0.23 |
eGFR (mL/min/m2) |
83.4 ± 24.4 |
74.5 ± 24.2 |
91.4 ± 21.9 |
<0.01 |