Bleeding disorders in girls and women: setting the scene
, 
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Michelle Lavin
Irish Centre for Vascular Biology, Royal College of Surgeons in IrelandDublin, Ireland
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oraz 21 paź 2019
O artykule
Kategoria artykułu: Women With Bleeding Disorders
Data publikacji: 21 paź 2019
Zakres stron: 3 - 9
DOI: https://doi.org/10.17225/jhp00138
Słowa kluczowe
© 2019 Naja Skouw-Rasmussen, Michelle Lavin, Minette van der Ven, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Figure 1
![Proportions of women receiving treatment for their bleeding disorder [1]](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/647217bf215d2f6c89dbbb0a/j_jhp00138_fig_001.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20250913%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20250913T113516Z&X-Amz-Expires=3600&X-Amz-Signature=3a99416f3fbfb05acd93ab39efc13e6a8954edf1fdc77f3755feca8d65bccf18&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)
Figure 2
![Menorrhagia bleeding scores in women with low von Willebrand factor [4]The bar charts compare the ISTH-BAT and Condensed MCMDM-1 VWD menorrhagia-domain scores among women in the Low von Willebrand in Ireland Cohort (LoVIC) study, based on identical clinical information[4]](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/647217bf215d2f6c89dbbb0a/j_jhp00138_fig_002.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20250913%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20250913T113516Z&X-Amz-Expires=3600&X-Amz-Signature=1630404a358989868916735ae0abf725e75f4d3381e90dee03bbbf95a6645931&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)
VWD type among survey respondents (N=198) [1]
| VWD | PERCENTAGE |
|---|---|
| Type 1 | 40% |
| Type 2 | 40% |
| Type 3 | 19% |
| Type 1/2 | 1% |
Platelet disorders among survey respondents (N=63) [1]
| PLATELET DISORDER | PERCENTAGE |
|---|---|
| Immune thrombocytopenic purpura (ITP) | 40% |
| Glanzmann thrombasthenia | 8% |
| Storage pool deficiency | 6% |
| Thrombocytopathy | 3% |
| Bernard-Soulier syndrome | 2% |
| Unknown | 41% |
Types of bleeding disorders among survey respondents [1]
| BLEEDING DISORDER | NUMBER | PERCENTAGE |
|---|---|---|
| Von Willebrand disease | 198 | 27.93% |
| Carrier <40% 74% Haemophilia A; 26% Haemophilia B | 193 | 27.22% |
| Carrier >40% 74% Haemophilia A; 26% Haemophilia B | 169 | 23.84% |
| Platelet disorders | 63 | 8.89% |
| Other factor deficiencies | 37 | 5.22% |
| Combined deficiencies | 31 | 4.37% |
| Unknown | 18 | 2.54% |
Personal statements about the impact of menstruation
| • | “Needed blood transfusion of two units - as a result missed out on a new career” |
| • | “Have to plan bathroom times between appointments. Up to 40 changes a day” |
| • | Had “a bandage and tampon at the same time” and “had a change of clothes at work” |
| • | Severe bleeding for “over ten years resulting hysterectomy at 38” |
| • | “I would regularly change sanitary protection and 20 minutes later have blood flowing down my legs“ |
| • | “I would have to stay in bed for three to four days a month because I was so exhausted” |