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Expression of autophagic and ubiquitin–proteasome proteins in the peripheral nervous system after nerve injury

Sithiporn Agthong
Sithiporn Agthong
, 
Marisa Rodtayoy
Marisa Rodtayoy
 oraz 
Atitaya Roumwong
Atitaya Roumwong
   | 04 cze 2020
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Article Category: Brief communication (original)
Data publikacji: 04 cze 2020
Zakres stron: 173 - 178
DOI: https://doi.org/10.1515/abm-2019-0057
Słowa kluczowe
© 2019 Sithiporn Agthong et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Figure 1

p62 protein in the right (R) (white bar), left proximal (LP) (light gray bar), and left distal (LD) (dark gray bar) sciatic nerves of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM. *P < 0.05 vs. R, #P < 0.01 vs. R.
p62 protein in the right (R) (white bar), left proximal (LP) (light gray bar), and left distal (LD) (dark gray bar) sciatic nerves of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM. *P < 0.05 vs. R, #P < 0.01 vs. R.

Figure 2

Beclin-1 protein in the right (R) (white bar), left proximal (LP) (light gray bar), and left distal (LD) (dark gray bar) sciatic nerves of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM.
Beclin-1 protein in the right (R) (white bar), left proximal (LP) (light gray bar), and left distal (LD) (dark gray bar) sciatic nerves of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM.

Figure 3

p62 protein in the right (white bars) and left (light-gray bars) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM.
p62 protein in the right (white bars) and left (light-gray bars) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM.

Figure 4

Beclin-1 protein in the right (R, white bars) and left (L, gray bars) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM.
Beclin-1 protein in the right (R, white bars) and left (L, gray bars) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time point. Error bars represent SEM.

Figure 5

Muscle ring finger-1 protein in the right (R, white bars) and left (L, left bars) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time-point. Error bars represent SEM.
Muscle ring finger-1 protein in the right (R, white bars) and left (L, left bars) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the average protein level at each time-point. Error bars represent SEM.

Figure 6

Ubiquitinated protein in the right (R) and left (L) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the left/right ratio at each time point. Error bars represent SEM.
Ubiquitinated protein in the right (R) and left (L) L4-6 dorsal root ganglia of rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush (n = 7 for each time point). Representative immunoblots are shown above. The bar chart demonstrates the left/right ratio at each time point. Error bars represent SEM.

Figure 7

Representative immunoblot of dorsal root ganglia from rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush, probed for beta-actin.
Representative immunoblot of dorsal root ganglia from rats sacrificed at day 1 (D1), day 3 (D3), day 7 (D7), and day 14 (D14) after nerve crush, probed for beta-actin.
eISSN:
1875-855X
Język:
Angielski
Częstotliwość wydawania:
6 razy w roku
Dziedziny czasopisma:
Medicine, Assistive Professions, Nursing, Basic Medical Science, other, Clinical Medicine
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