| | 1. Food preservation | | |
AMA-K, Leucocin K7 | L. plantarum AMA-K | Enterococcus spp., E. coli,K. pneumoniae, Listeria spp. | Amasi, fermented milk product | (Todorov 2008) |
Aureocin A70 | S. aureus A70 | L. monocytogenes | Dairy product | (Carlin Fagundes et al. 2016) |
Bacteriocin 32Y | L.curvatus | L. monocytogenes | Pork and beef | (Gálvez et al. 2007) |
Bacteriocin GP1 | L. rhamnosus GP1 | Staphylococcus sp.,Aeromonas sp., Lactobacillus sp.,Pseudomonas sp., Vibrio sp. | Fish | (Sarika et al. 2019) |
Bovicin HC5 + Nisin | Streptococcus bovis HC5 | L. monocytogenes, S. aureus | Fresh cheese | (Pimentel-Filho et al. 2014) |
Divergicin M35 | Carnobacteriumdivergens M35 | L. monocytogenes | Smoked fish | (Benabbou et al. 2020) |
Enterocin | E.faecium FAIR-E 198 | Listeria spp. | Feta cheese | (Sarantinopoulos et al. 2002) |
Enterocin 416K1 | E.casseliflavus IM 416K1 | L. monocytogenes NCTC 10888 | Cottage cheese | (Iseppi et al. 2008) |
Enterocin AS-48 | Enterococcus sp. | L. monocytogenes, B. cereus | Cheese, vegetable, purees, and soups | (Gálvez et al. 2007) |
H1, H2, H3, H4 | Bacillus sp. | V. alginolyticus, Aeromonas hydrophilla, P. stutzeri | Antimicrobial used in fish | (Feliatra et al. 2018) |
Lacticin 3147 | L.lactis | L. monocytogenes | Matured and cottage cheese | (Mills et al. 2017) |
Lacticin NK24 | L. lactis | Leuconostoc mesenteroidesKCCM 11324 | Seafood | (Lee and Paik 2001) |
Leucocin K7 | L. mesenteroides K7 | L. monocytogenes | Dairy product | (Shi et al. 2016) |
Mecedocin | S.macedonicusACA-DC 198 | C. tyrobutyricum LMG 1285T | Kasseri cheese | (Anastasiou et al. 2009) |
NE | L.gasseri K7 (Rifr),L. gasseri LF221(Rifr) | C. tyrobutyricum | Semi-mature cheese | (Bogovič Matijašić et al. 2007) |
Nisin | Lactococcus spp.,Streptococcus spp. | L. monocytogenes, Clostridium botulinum, S. mutans,L. innocua, S. aureus,S. pneumoniae, B. cereus | Dairy products, meat, seafood | (Juturu and Wu 2018) |
Pediocin PA1 | P.acidilactici | L. monocytogenes | Dairy products, meat | (Liu et al. 2008) |
Plant-made salmocins | Salmonella spp. | S. enterica | Red meat | (Schneider et al. 2018) |
Plant-made colicins (GRN 676, GRN 593) | E.coli | E. coli, P. aeruginosa,Salmonella spp. | Meat, fruits, or vegetables | (Hahn-Löbmann et al. 2019) |
Psicolin 126, carnocyclin A | C. maltoaromaticum | L. monocytogenes | Ready-to-eat meat products | (Liu et al. 2014) |
Reuterin | L. reuteri | E.coli, S. aureus,Candida albicans | Food preservation | (Helal et al. 2016) |
Sakacin P | L.sakei | L.monocytogenes | Beef and Salmon | (Teneva-Angelova et al. 2018) |
Thuricin BtCspB | B. thuringiensis | B.cereus | Food preservation and disease associate to B. cereus | (Huang et al. 2016) |
| | 2. Bacterial infections | | |
ABP118 | L.salivarius subsp. salivarius UCC118 | Bacteroides | Antimicrobial agent | (Riboulet-Bisson et al. 2012) |
Colicins Js and Z | E.coli | Enteroinvasive, E. coli (EIEC) and Shigella | Gastrointestinal infections | Bosák et al. 2021 |
Divercin V41 | C.divergens | L. monocytogenes | Antimicrobial agent | (Rihakova et al. 2010) |
Duramycin | Streptomyces cinnamoneus | B. subtilis | Antimicrobial, anti-viral, immunomodulation, ion channel modulation, treatment of atherosclerosis and cystic fibrosis | (Huo et al. 2017) |
Enterocin CRL35 | E.mundtii | L. monocytogenes | Gastrointestinal infections | (Salvucci et al. 2012) |
Epidermin and mersacidin-like peptides | S.epidermidis | P. acnes | Acne, folliculitis. | (Gillor et al. 2008) |
Gallidermin/epidermin | S.gallinarum | S. epidermidis, S. aureus | Skin infections or associated with implants and prostheses | (Bengtsson et al. 2018; Bonelli et al. 2006) |
Gassericin E | L.gasseri EV1461 | Pathogens associated with vaginosis | Vaginal infections | (Maldonado-Barragán et al. 2016) |
Haemocin type B | Haemophilushaemolyticus | H. influenza | Respiratory infections | (Latham et al. 2017) |
Lactocin 160 | L.rhamnosus | G. vaginalis | Urogenital tract infections, bacterial vaginosis | (Turovskiy et al. 2009) |
Laterosporulin10 | Brevibacillus sp. strain SKDU10 | S. aureus, Mycobacterium tuberculosis (Mtb H37Rv),M. smegmatis MC2 155 | Human microbial pathogens | (Baindara et al. 2016) |
Mersacidin | B.amyloliquefaciens | Methicillin-resistantS. aureus (MRSA) | Skin infection | (Kruszewska et al. 2004) |
Microcin J25 (lasso-peptide) | E.coli | S.enterica, E.coli, S.flexnerii | Gastrointestinal infections | (Dobson et al. 2012) |
Nisin A, Nisin Z, Nisaplin | L.lactis | S.mutans, S.aureus, E.faecalis,S.mastitis, C.albicans | Gastrointestinal, respiratory, and skin infections, oral health | (Shin et al. 2016) |
Oralpeace TM (encapsulated nisin) | L.lactis | S. mutans, P. gingivalis | Dental caries, gingivitis | (Perez et al. 2014) |
Piscicolin 126 | Carnobacterium spp. | Listeria spp. | Antimicrobial agent | (Miller and McMullen 2014) |
Plantaricin 423 | L.plantarum | Listeria spp. | Antimicrobial agent | (Guralp et al. 2013) |
PLNC8 αβ | L.plantarum | Staphylococcus sp.,Porphyromonas gingivalis | Antimicrobial agent | (Bengtsson et al. 2020) |
R-pyocins | P.aeruginosa | P. aeruginosa | Antimicrobial agent | (Redero et al. 2018) |
TOMM Streptolysin S (SLS) | S.pyogenes | Clostridium sp.,Listeria sp. | Hemolytic and cytotoxic activity against macrophages and neutrophils | (Molloy et al. 2015) |
| | 3. Anticancer drugs | | |
| | Cancer cell lines | | |
Azurin | P.aeruginosa | MCF-7, UISO-Mel-2, osteosarcoma (U2OS) | (Nguyen and Nguyen 2016) |
Bovicin HC5 | S.bovis HC5 | MCF-7, HepG2 | (Rodrigues et al. 2019) |
Colicin E3 | E.coli | P388, HeLa, HS913T | (Kohoutova et al. 2014 |
Duramycin | S.cinnamoneus | AsPC-1, Caco-2, Colo320, CT116, JJN3, Lovo, MCF-7, MDA-B-231, MIA PaCa-2 | (Rodrigues et al. 2019) |
Enterocin LNS18 | E.thailandicus | HepG2 | (Al-Madboly et al. 2020) |
Laterosporulin LS10 | Brevibacillus latero– | HeLa, MCF-7, H1299, HEK293T, HT1080 | (Baindara et al. 2016) |
| sporus SKDU10 | | |
M2163, M2386 | L.casei ATCC 334 | SW480 | (Rodrigues et al. 2019) |
Microcin E492 | K.pneumoniae | HeLa, Burkitt lymphoma variant (RJ2.25) | (Kaur and Kaur 2015) |
Nisin A | L.lactis | Head and neck squamous cell carcinoma (HNSCC) | (Shin et al. 2016) |
Pediocin K2a2-3 | P.acidilactici K2a2-3 | HT2a, HeLa | (Villarante et al. 2011) |
Pediocin CP2 | P.acidilactici CP2 MTCC501 | HeLa, MCF-7, HepG2, murine myeloma (Sp2/0-Ag 14) | (Kumar et al. 2012) |
Pep27anal2 | S.pneumoniae | Jurkat, HL-60, AML-2, MCF-7, SNU-601 | (Rodrigues et al. 2019) |
Plantaricin A | L.plantarum C11 | GH4, Reh, Jurkat, PC12, N2A | (Sand et al. 2013) |
Plantaricin P1053 | L.plantarum PBS067 | E705 | (De Giani et al. 2019) |
Pyocin S2 | P.aeruginosa 42A | HepG2, Im9, murine tumor (mKS-A TU-7), human fetal foreskin fibroblast (HFFF) | (Abdi-Ali et al. 2004) |
Sungsanpin | Streptomyces spp. | A549 | (Um et al. 2013) |
Smegmatocin | M.smegmatis 14468 | HeLa, AS-II, HGC-27, mKS-A TU-7 | (Kaur and Kaur 2015) |