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Cai T, Nesi G, Tinacci G, Giubilei G, Gavazzi A, Mondaini N, et al. Clinical importance of lymph node density in predicting outcome of prostate cancer patients. J Surg Res 2011; 167: 267-72. 10.1016/j.jss.2009.05.00419783007CaiTNesiGTinacciGGiubileiGGavazziAMondainiNClinical importance of lymph node density in predicting outcome of prostate cancer patientsJ Surg Res20111672677210.1016/j.jss.2009.05.004Open DOISearch in Google Scholar
Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, van der Kwast T, et al. EAU guidelines on prostate cancer. part 1: screening, diagnosis, and local treatment with curative intent-update 2013. Eur Urol 2014; 65: 124-37. 10.1016/j.eururo.2013.09.04624207135HeidenreichABastianPJBellmuntJBollaMJoniauSvan der KwastTEAU guidelines on prostate cancer. part 1: screening, diagnosis, and local treatment with curative intent-update 2013Eur Urol2014651243710.1016/j.eururo.2013.09.046Open DOISearch in Google Scholar
Heidenreich A, Varga Z, Von Knobloch R. Extended pelvic lymphadenectomy in patients undergoing radical prostatectomy: high incidence of lymph node metastasis. J Urol 2002; 167: 1681-6.10.1016/S0022-5347(05)65177-411912387HeidenreichAVargaZVon KnoblochR.Extended pelvic lymphadenectomy in patients undergoing radical prostatectomy: high incidence of lymph node metastasisJ Urol200216716816Open DOISearch in Google Scholar
Jager GJ, Barentsz JO, Oosterhof GO, Witjes JA, Ruijs SJ. Pelvic adenopathy in prostatic and urinary bladder carcinoma: MR imaging with a three-dimensional TI-weighted magnetization-prepared-rapid gradient-echo sequence. AJR Am J Roentgenol 1996; 167: 1503-7. 10.2214/ajr.167.6.89565858956585JagerGJBarentszJOOosterhofGOWitjesJARuijsSJ.Pelvic adenopathy in prostatic and urinary bladder carcinoma: MR imaging with a three-dimensional TI-weighted magnetization-prepared-rapid gradient-echo sequenceAJR Am J Roentgenol19961671503710.2214/ajr.167.6.8956585Open DOISearch in Google Scholar
Wang L, Hricak H, Kattan MW, Schwartz LH, Eberhardt SC, Chen HN, et al. Combined endorectal and phased-array MRI in the prediction of pelvic lymph node metastasis in prostate cancer. AJR Am J Roentgenol 2006; 186: 743-8. 10/2214/AJR.04.168216498101WangLHricakHKattanMWSchwartzLHEberhardtSCChenHNCombined endorectal and phased-array MRI in the prediction of pelvic lymph node metastasis in prostate cancerAJR Am J Roentgenol2006186743810/2214/AJR.04.1682Open DOISearch in Google Scholar
Borley N, Fabrin K, Sriprasad S, Mondaini N, Thompson P, Muir G, et al. Laparoscopic pelvic lymph node dissection allows significantly more accurate staging in “high-risk” prostate cancer compared to MRI or CT. Scand J Urol Nephrol 2003; 37: 382-6. 10.1080/0036559031000630914594685BorleyNFabrinKSriprasadSMondainiNThompsonPMuirGLaparoscopic pelvic lymph node dissection allows significantly more accurate staging in “high-risk” prostate cancer compared to MRI or CTScand J Urol Nephrol200337382610.1080/00365590310006309Open DOISearch in Google Scholar
Beer AJ, Eiber M, Souvatzoglou M, Holzapfel K, Ganter C, Weirich G, et al. Restricted water diffusibility as measured by diffusion-weighted MR imaging and choline uptake in (11)C-choline PET/CT are correlated in pelvic lymph nodes in patients with prostate cancer. Mol Imaging Biol 2011; 13: 352-61. 10.1007/s11307-010-0337-620490932BeerAJEiberMSouvatzoglouMHolzapfelKGanterCWeirichGRestricted water diffusibility as measured by diffusion-weighted MR imaging and choline uptake in (11)C-choline PET/CT are correlated in pelvic lymph nodes in patients with prostate cancerMol Imaging Biol2011133526110.1007/s11307-010-0337-6Open DOISearch in Google Scholar
Budiharto T, Joniau S, Lerut E, Van den Bergh L, Mottaghy F, Deroose CM, et al. Prospective evaluation of 11C-choline positron emission tomography/ computed tomography and diffusion-weighted magnetic resonance imaging for the nodal staging of prostate cancer with a high risk of lymph node metastases. Eur Urol 2011; 60: 125-30. 10.1016/j.eururo.2011.01.015.21292388BudihartoTJoniauSLerutEVan den BerghLMottaghyFDerooseCMProspective evaluation of 11C-choline positron emission tomography/ computed tomography and diffusion-weighted magnetic resonance imaging for the nodal staging of prostate cancer with a high risk of lymph node metastasesEur Urol2011601253010.1016/j.eururo.2011.01.015Open DOISearch in Google Scholar
Eiber M, Beer AJ, Holzapfel K, Tauber R, Ganter C, Weirich G, et al. Preliminary results for characterization of pelvic lymph nodes in patients with prostate cancer by diffusion-weighted MR-imaging. Inves Radiol 2010; 45: 15-23. 10.1097/RLI.0b013e3181bbdc2fEiberMBeerAJHolzapfelKTauberRGanterCWeirichGPreliminary results for characterization of pelvic lymph nodes in patients with prostate cancer by diffusion-weighted MR-imagingInves Radiol201045152310.1097/RLI.0b013e3181bbdc2fOpen DOISearch in Google Scholar
Vag T, Heck MM, Beer AJ, Souvatzoglou M, Weirich G, Holsapfel K, et al. Preoperative lymph node staging in patients with primary prostate cancer: comparison and correlation of quantitative imaging parameters in diffusion-weighted imaging and 11C-choline PET/CT. Eur Radiology 2014; 24: 1821-6. 10.1007/s00330-014-3240-8.VagTHeckMMBeerAJSouvatzoglouMWeirichGHolsapfelKPreoperative lymph node staging in patients with primary prostate cancer: comparison and correlation of quantitative imaging parameters in diffusion-weighted imaging and 11C-choline PET/CTEur Radiology2014241821610.1007/s00330-014-3240-8Open DOISearch in Google Scholar
von Below C, Daouacher G, Wassberg C, Grzegorek R, Gestblom C, Sörensen J, et al. Validation of 3 T MRI including diffusion-weighted imaging for nodal staging of newly diagnosed intermediate-and high-risk prostate cancer. Clin Radiol 2016; 71: 328-34. 10.1016/j.crad.2015.12.001.von BelowCDaouacherGWassbergCGrzegorekRGestblomCSörensenJValidation of 3 T MRI including diffusion-weighted imaging for nodal staging of newly diagnosed intermediate-and high-risk prostate cancerClin Radiol2016713283410.1016/j.crad.2015.12.001Open DOISearch in Google Scholar
Vallini V, Ortori S, Boraschi P, Manassero F, Gabelloni M, Faggioni L, et al. Staging of pelvic lymph nodes in patients with prostate cancer: Usefulness of multiple b value SE-EPI diffusion-weighted imaging on a 3.0 T MR system. Eur J Radiol Open 2016; 3: 16-21. 10.1016/j.ejro.2015.11.004.ValliniVOrtoriSBoraschiPManasseroFGabelloniMFaggioniLStaging of pelvic lymph nodes in patients with prostate cancer: Usefulness of multiple b value SE-EPI diffusion-weighted imaging on a 3.0 T MR systemEur J Radiol Open20163162110.1016/j.ejro.2015.11.004Open DOISearch in Google Scholar
Beheshti M, Imamovic L, Broinger G, Vali R, Waldenberger P, Stoiber F, et al. 18F choline PET/CT in the preoperative staging of prostate cancer in patients with intermediate or high risk of extracapsular disease: a prospective study of 130 patients. Radiology 2010; 254: 925-33. 10.1148/radiol.09090413.20177103BeheshtiMImamovicLBroingerGValiRWaldenbergerPStoiberF18F choline PET/CT in the preoperative staging of prostate cancer in patients with intermediate or high risk of extracapsular disease: a prospective study of 130 patientsRadiology20102549253310.1148/radiol.09090413Open DOISearch in Google Scholar
Heck MM, Souvatzoglou M, Retz M, Nawroth R, Kübler H, Maurer T, et al. Prospective comparison of computed tomography, diffusion-weighted magnetic resonance imaging and [11C]choline positron emission tomography/ computed tomography for preoperative lymph node staging in prostate cancer patients. Eur J Nucl Med Mol I 2014; 41: 694-701. 10.1007/s00259-013-2634-1.HeckMMSouvatzoglouMRetzMNawrothRKüblerHMaurerTProspective comparison of computed tomography, diffusion-weighted magnetic resonance imaging and [11C]choline positron emission tomography/ computed tomography for preoperative lymph node staging in prostate cancer patientsEur J Nucl Med Mol I20144169470110.1007/s00259-013-2634-1Open DOISearch in Google Scholar
Contractor K, Challapalli A, Barwick T, Winkler M, Hellawell G, Hazell S, et al. Use of [11C]choline PET-CT as a noninvasive method for detecting pelvic lymph node status from prostate cancer and relationship with choline kinase expression. Clin Cancer Res 2011; 17: 7673-83. 10.1158/1078-0432.CCR-11-2048.22038995ContractorKChallapalliABarwickTWinklerMHellawellGHazellSUse of [11C]choline PET-CT as a noninvasive method for detecting pelvic lymph node status from prostate cancer and relationship with choline kinase expressionClin Cancer Res20111776738310.1158/1078-0432.CCR-11-2048Open DOISearch in Google Scholar
Poulsen MH, Bouchelouche K, Hoilund-Carlsen PF, Petersen H, Gerke O, Steffansen SI, et al. [18F]fluoromethylcholine (FCH) positron emission tomography/computed tomography (PET/CT) for lymph node staging of prostate cancer: a prospective study of 210 patients. BJU Int 2012; 110: 1666-71. 10.1111/j.1464-410X.2012.11150.x.22520686PoulsenMHBoucheloucheKHoilund-CarlsenPFPetersenHGerkeOSteffansenSI[18F]fluoromethylcholine (FCH) positron emission tomography/computed tomography (PET/CT) for lymph node staging of prostate cancer: a prospective study of 210 patientsBJU Int201211016667110.1111/j.1464-410X.2012.11150.xOpen DOISearch in Google Scholar
Haseebuddin M, Dehdashti F, Siegel BA, Liu J, Roth EB, Nepple KG, et al. 11C-acetate PET/CT before radical prostatectomy: nodal staging and treatment failure prediction. J Nucl Med 2013; 54: 699-706. 10.2967/jnumed.112.111153.23471311HaseebuddinMDehdashtiFSiegelBALiuJRothEBNeppleKG11C-acetate PET/CT before radical prostatectomy: nodal staging and treatment failure predictionJ Nucl Med20135469970610.2967/jnumed.112.111153Open DOISearch in Google Scholar
Daouacher G, von Below C, Gestblom C, Ahlström H, Grzegorek R, Wassberg C, et al. Laparoscopic extended pelvic lymph node (LN) dissection as validation of the performance of [C]-acetate positron emission tomography/computer tomography in the detection of LN metastasis in intermediate- and high-risk prostate cancer. BJU Int 2016; 118: 77-83. 10.1111/bju.13202.26074275DaouacherGvon BelowCGestblomCAhlströmHGrzegorekRWassbergCLaparoscopic extended pelvic lymph node (LN) dissection as validation of the performance of [C]-acetate positron emission tomography/computer tomography in the detection of LN metastasis in intermediate- and high-risk prostate cancerBJU Int2016118778310.1111/bju.13202Open DOISearch in Google Scholar
Swinnen JV, Roskams T, Joniau S, Van Poppel H, Oyen R, Baert L, et al. Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer. Int J Cancer 2002; 98: 19-22.10.1002/ijc.1012711857379SwinnenJVRoskamsTJoniauSVan PoppelHOyenRBaertLOverexpression of fatty acid synthase is an early and common event in the development of prostate cancerInt J Cancer2002981922Open DOISearch in Google Scholar
Dhanasekaran SM, Barrette TR, Ghosh D, Shah R, Varambally S, Kurachi K, et al. Delineation of prognostic biomarkers in prostate cancer. Nature 2001; 412: 822-6. 10.1038/3509058511518967DhanasekaranSMBarretteTRGhoshDShahRVaramballySKurachiKDelineation of prognostic biomarkers in prostate cancerNature2001412822610.1038/35090585Open DOISearch in Google Scholar
Vavere AL, Kridel SJ, Wheeler FB, Lewis JS. 1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer. J Nucl Med 2008; 49: 327-34. 10.2967/jnumed.107.04667218199615VavereALKridelSJWheelerFBLewisJS.1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancerJ Nucl Med2008493273410.2967/jnumed.107.046672Open DOISearch in Google Scholar
Le Bihan D, Breton E, Lallemand D, Aubin ML, Vignaud J, Laval-Jeantet M. Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology 1988; 168: 497-505. 10.1148/radiology.168.2.33936713393671Le BihanDBretonELallemandDAubinMLVignaudJLaval-JeantetM.Separation of diffusion and perfusion in intravoxel incoherent motion MR imagingRadiology198816849750510.1148/radiology.168.2.3393671Open DOISearch in Google Scholar
Sato C, Naganawa S, Nakamura T, Kumada H, Miura S, Takizawa O, et al. Differentiation of noncancerous tissue and cancer lesions by apparent diffusion coefficient values in transition and peripheral zones of the prostate. J Magn Reson Imaging 2005; 21: 258-62. 10.1002/jmri.2025115723379SatoCNaganawaSNakamuraTKumadaHMiuraSTakizawaODifferentiation of noncancerous tissue and cancer lesions by apparent diffusion coefficient values in transition and peripheral zones of the prostateJ Magn Reson Imaging2005212586210.1002/jmri.20251Open DOISearch in Google Scholar
Tanimoto A, Nakashima J, Kohno H, Shinmoto H, and Kuribayashi S. Prostate cancer screening: the clinical value of diffusion-weighted imaging and dynamic MR imaging in combination with T2-weighted imaging. J Magn Reson Imaging 2007; 25: 146-52. 10.1161/01.ATV.0000251615.61858.3317139633TanimotoANakashimaJKohnoHShinmotoHKuribayashiS.Prostate cancer screening: the clinical value of diffusion-weighted imaging and dynamic MR imaging in combination with T2-weighted imagingJ Magn Reson Imaging2007251465210.1161/01.ATV.0000251615.61858.33Open DOISearch in Google Scholar
Verma S, and Rajesh A. A clinically relevant approach to imaging prostate cancer: review. AJR Am Journal Roentgenol 2011; 196: S1-10 Quiz S11-14. 10.2214/AJR.09.7196VermaSRajeshA.A clinically relevant approach to imaging prostate cancer: reviewAJR Am Journal Roentgenol2011196S1-10S11-1410.2214/AJR.09.7196Open DOISearch in Google Scholar
D’Amico AV, Schultz D, Loffredo M, Dugal R, Hurwitz M, Kaplan I, et al. Biochemical outcome following external beam radiation therapy with or without androgen suppression therapy for clinically localized prostate cancer. JAMA 2000; 284: 1280-3.10.1001/jama.284.10.128010979115D’AmicoAVSchultzDLoffredoMDugalRHurwitzMKaplanIBiochemical outcome following external beam radiation therapy with or without androgen suppression therapy for clinically localized prostate cancerJAMA200028412803Open DOISearch in Google Scholar
Briganti A, Gallina A, Suardi N, Chun FK, Walz J, Heuer R, et al. A nomogram is more accurate than a regression tree in predicting lymph node invasion in prostate cancer. BJU Int 2008; 101: 556-60. 10.1111/j.1464-410X.2007.07321.x18005204BrigantiAGallinaASuardiNChunFKWalzJHeuerRA nomogram is more accurate than a regression tree in predicting lymph node invasion in prostate cancerBJU Int20081015566010.1111/j.1464-410X.2007.07321.xOpen DOISearch in Google Scholar
Polanec SH, Andrzejewski P, Baltzer PAT, Helbich TH, Stiglbauer A, Georg D, et al. Multiparametric [11C]Acetate positron emission tomography-magnetic resonance imaging in the assessment and staging of prostate cancer. PLoS One 2017; 12: e0180790. 10.1371/journal.pone.018079028719629PolanecSHAndrzejewskiPBaltzerPATHelbichTHStiglbauerAGeorgDMultiparametric [11C]Acetate positron emission tomography-magnetic resonance imaging in the assessment and staging of prostate cancerPLoS One201712e018079010.1371/journal.pone.0180790Open DOISearch in Google Scholar
Park SY, Oh YT, Jung DC, Cho NH, Choi YD, Rha KH. Prediction of micrometastasis (< 1 cm) to pelvic lymph nodes in prostate cancer: Role of preoperative MRI. AJR Am J Rroentgenol 2015; 205: W328-34. 10.2214/AJR.14.14138ParkSYOhYTJungDCChoNHChoiYDRhaKH.Prediction of micrometastasis (< 1 cm) to pelvic lymph nodes in prostate cancer: Role of preoperative MRIAJR Am J Rroentgenol2015205W3283410.2214/AJR.14.14138Open DOISearch in Google Scholar
Batra V, Gautam G, Jaipuria J, Suryavanshi M, Khera R, Ahlawat R. Predictive factors for lymph node positivity in patients undergoing extended pelvic lymphadenectomy during robot assisted radical prostatectomy. Indian J Urol 2015; 31: 217-22. 10.4103/0970-1591.15691826166965BatraVGautamGJaipuriaJSuryavanshiMKheraRAhlawatR.Predictive factors for lymph node positivity in patients undergoing extended pelvic lymphadenectomy during robot assisted radical prostatectomyIndian J Urol2015312172210.4103/0970-1591.156918Open DOISearch in Google Scholar
Herlemann A, Wenter V, Kretschmer A, Thierfelder KM, Bartenstein P, Faber C, et al. 68Ga-PSMA Positron emission tomography/computed tomography provides accurate staging of lymph node regions prior to lymph node dissection in patients with prostate cancer. Eur Urol 2016; 70: 553-7. 10.1016/j.eururo.2015.12.05126810345HerlemannAWenterVKretschmerAThierfelderKMBartensteinPFaberC68Ga-PSMA Positron emission tomography/computed tomography provides accurate staging of lymph node regions prior to lymph node dissection in patients with prostate cancerEur Urol201670553710.1016/j.eururo.2015.12.051Open DOISearch in Google Scholar
van Leeuwen PJ, Emmett L, Ho B, Delprado W, Ting F, Nguyen Q, et al. Prospective evaluation of 68Gallium-prostate-specific membrane antigen positron emission tomography/computed tomography for preoperative lymph node staging in prostate cancer. BJU Int 2017; 119: 209-15. 10.1111/bju.1354027207581van LeeuwenPJEmmettLHoBDelpradoWTingFNguyenQProspective evaluation of 68Gallium-prostate-specific membrane antigen positron emission tomography/computed tomography for preoperative lymph node staging in prostate cancerBJU Int20171192091510.1111/bju.13540Open DOISearch in Google Scholar
Uprimny C, Kroiss AS, Decristoforo C, Fritz J, von Guggenberg E, Kendler D, et al. 68Ga-PSMA-11 PET/CT in primary staging of prostate cancer: PSA and Gleason score predict the intensity of tracer accumulation in the primary tumour. Eur J Nucl Med Mol I 2017; 44: 941-9. 10.1007/s00259-017-3631-6UprimnyCKroissASDecristoforoCFritzJvon GuggenbergEKendlerD68Ga-PSMA-11 PET/CT in primary staging of prostate cancer: PSA and Gleason score predict the intensity of tracer accumulation in the primary tumourEur J Nucl Med Mol I201744941910.1007/s00259-017-3631-6Open DOISearch in Google Scholar
Kallehauge JF, Tanderup K, Haack S, Nielsen T, Muren LP, Fokdal L, et al. Apparent Diffusion Coefficient (ADC) as a quantitative parameter in diffusion weighted MR imaging in gynecologic cancer: Dependence on b-values used. Acta Oncol 2010; 49: 1017-22. 10.3109/0284186X.2010.50030520831490KallehaugeJFTanderupKHaackSNielsenTMurenLPFokdalLApparent Diffusion Coefficient (ADC) as a quantitative parameter in diffusion weighted MR imaging in gynecologic cancer: Dependence on b-values usedActa Oncol20104910172210.3109/0284186X.2010.500305Open DOISearch in Google Scholar
Sasaki M, Yamada K, Watanabe Y, Matsui M, Ida M, Fujiwara S, et al. Variability in absolute apparent diffusion coefficient values across different platforms may be substantial: a multivendor, multi-institutional comparison study. Radiology 2008; 249: 624-30. 10.1148/radiol.249207168118936317SasakiMYamadaKWatanabeYMatsuiMIdaMFujiwaraSVariability in absolute apparent diffusion coefficient values across different platforms may be substantial: a multivendor, multi-institutional comparison studyRadiology20082496243010.1148/radiol.2492071681Open DOISearch in Google Scholar
Padhani AR, Liu G, Koh DM, Chenevert TL, Thoeny HC, Takahara T, et al. Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations. Neoplasia 2009; 11: 102-25.1918640510.1593/neo.81328PadhaniARLiuGKohDMChenevertTLThoenyHCTakaharaTDiffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendationsNeoplasia20091110225Search in Google Scholar
Heesakkers RA, Hövels AM, Jager GJ, van den Bosch HC, Witjes JA, Raat HP, et al. MRI with a lymph-node-specific contrast agent as an alternative to CT scan and lymph-node dissection in patients with prostate cancer: a prospective multicohort study. Lancet Oncol 2008; 9: 850-6. 10.1016/S1470-2045(08)70203-1HeesakkersRAHövelsAMJagerGJvan den BoschHCWitjesJARaatHPMRI with a lymph-node-specific contrast agent as an alternative to CT scan and lymph-node dissection in patients with prostate cancer: a prospective multicohort studyLancet Oncol20089850610.1016/S1470-2045(08)70203-1Open DOISearch in Google Scholar
Thoeny HC, Froehlich JM, Triantafyllou M, Huesler J, Bains LJ, Vermathen P, et al. Metastases in normal-sized pelvic lymph nodes: detection with diffusion-weighted MR imaging. Radiology 2014; 273: 125-35. 10.1148/radiol.1413292124893049ThoenyHCFroehlichJMTriantafyllouMHueslerJBainsLJVermathenPMetastases in normal-sized pelvic lymph nodes: detection with diffusion-weighted MR imagingRadiology20142731253510.1148/radiol.14132921Open DOISearch in Google Scholar
