[1. Jayaraj RL, Azimullah S, Beiram R, Jalal FY, Rosenberg GA. Neuroinflammation: friend and foe for ischemic stroke. J Neuroinflammation. 2019;16(1):142.10.1186/s12974-019-1516-2661768431291966]Search in Google Scholar
[2. Ma Y, Liu Y, Zhang Z, Yang GY. Significance of Complement System in Ischemic Stroke: A Comprehensive Review. Aging Dis. 2019;10(2):429-62.10.14336/AD.2019.0119645704631011487]Search in Google Scholar
[3. Lallukka T, Ervasti J, Lundström E, Mittendorfer-Rutz E, Friberg E, Virtanen M, et al. Trends in diagnosis-specific work disability before and after stroke: A longitudinal population-based study in Sweden. J Am Heart Assoc. 2018;7(1):e006991.10.1161/JAHA.117.006991577896129301760]Search in Google Scholar
[4. Mondal NK, Behera J, Kelly KE, George AK, Tyagi PK, Tyagi N. Tetrahydrocurcumin epigenetically mitigates mitochondrial dysfunction in brain vasculature during ischemic stroke. Neurochem Int. 2019;122:120-38.10.1016/j.neuint.2018.11.015666626830472160]Search in Google Scholar
[5. Ham PB 3rd, Raju R. Mitochondrial function in hypoxic ischemic injury and influence of aging. Prog Neurobiol. 2017;157:92-116.10.1016/j.pneurobio.2016.06.006516173627321753]Search in Google Scholar
[6. Yang JL, Mukda S, Chen SD. Diverse roles of mitochondria in ischemic stroke. Redox Biol. 2018;16:263-75.10.1016/j.redox.2018.03.002585493029549824]Search in Google Scholar
[7. Hatefi Y. The mitochondrial electron transport and oxidative phosphorylation system. Annu. Rev. Biochem. 1985;54:1015-69.10.1146/annurev.bi.54.070185.0050552862839]Search in Google Scholar
[8. Liu F, Lu J, Manaenko A, Tang J, Hu Q. Mitochondria in Ischemic Stroke: New Insight and Implications. Aging Dis. 2018;9(5):924-37.10.14336/AD.2017.1126614758830271667]Search in Google Scholar
[9. Honda HM, Korge P, Weiss JN. Mitochondria and ischemia/reperfusion injury. Ann NY Acad Sci. 2005;1047:248-58.10.1196/annals.1341.02216093501]Search in Google Scholar
[10. Nguyen H, Zarriello S, Rajani M, Tuazon J, Napoli E, Borlongan CV. Understanding the Role of Dysfunctional and Healthy Mitochondria in Stroke Pathology and Its Treatment. Int J Mol Sci. 2018;19(7):2127.10.3390/ijms19072127607342130037107]Search in Google Scholar
[11. Bernardi P, Rasola A, Forte M, Lippe G. The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology. Physiol Rev. 2015;95(4):1111-55.10.1152/physrev.00001.2015460094926269524]Search in Google Scholar
[12. Hawkins BJ, Levin MD, Doonan PJ, Petrnko NB, Davis CW, Patel VV, et al. Mitochondrial complex II prevents hypoxic but not calcium- and proapoptotic Bcl-2 protein-induced mitochondrial membrane potential loss. J Biol Chem. 2010;285(34):26494-505.10.1074/jbc.M110.143164292408520566649]Search in Google Scholar
[13. Xiao Y, Zhang Z, Wang Y, Gao B, Chang J, Zhu D. Two-Stage Crystallization Combining Direct Succinimide Synthesis for the Recovery of Succinic Acid From Fermentation Broth. Front Bioeng Biotechnol. 2020;7:471.10.3389/fbioe.2019.00471697444932010679]Search in Google Scholar
[14. Volchegorskii IA, Miroshnichenko IY, Rassokhina LM, Faizullin RM, Malkin MР, Pryakhina KE, et.al. Comparative analysis of the anxiolytic effects of 3-hydroxypyridine and succinic acid derivatives. Bull Exp Biol Med. 2015;158(6): 756-61.10.1007/s10517-015-2855-325894772]Search in Google Scholar
[15. Ferro A, Carbone E, Zhang J, Marzouk E, Villegas M, Siegel A, et al. Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model. PLoS One. 2017;12(12):e0188425.10.1371/journal.pone.0188425571851529211771]Search in Google Scholar
[16. Weinberg JM, Venkatachalam MA, Roeser NF, Nissim I. Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates. Proc Natl Acad Sci USA. 2000;97(6):2826-31.10.1073/pnas.97.6.28261601410717001]Search in Google Scholar
[17. Nowak G, Clifton GL, Bakajsova D. Succinate ameliorates energy deficits and prevents dysfunction of complex I in injured renal proximal tubular cells. J Pharmacol Exp Ther. 2008;324(3):1155-62.10.1124/jpet.107.130872255327418055880]Search in Google Scholar
[18. Pozdnyakov DI, Nygaryan SA, Voronkov AV. Ethylmethylhydroxypyridine succinate, acetylcysteine and choline alphoscerate improve mitochondrial function under condition of cerebral ischemia in rat. Bangladesh Pharmacol. 2019;14(3):152-8.10.3329/bjp.v14i3.40977]Search in Google Scholar
[19. Tamura A, Graham DI, McCulloch J, Teasdale GM. Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab. 1981;1(1):53-60.10.1038/jcbfm.1981.67328138]Search in Google Scholar
[20. Patel SP, Sullivan PG, Pandya JD, et al. N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma. Exp Neurol. 2014;257:95-105.10.1016/j.expneurol.2014.04.026411414824805071]Search in Google Scholar
[21. Pozdnyakov DI, Voronkov AV, Miroshnichenko KA, Adzhiahmetova SL, Chervonnaya NM, Rukovitcina VM. Pyrimidine-4H-1OH derivatives restore mitochondrial function in experimental chronic traumatic encephalopathy. Pharmacologyonline.2019;3:36-45]Search in Google Scholar
[22. He F. Bradford Protein Assay. Bio-101:2015.e45.]Search in Google Scholar
[23. Zhyliuk V, Mamchur V, Pavlov S. Role of functional state of neuronal mitochondria of cerebral cortex in mechanisms of nootropic activity of neuroprotectors in rats with alloxan hyperglycemia. Eksperimental’naia i klinicheskaia farmakologiia. 2015;78: 10-4.]Search in Google Scholar
[24. Klacanova K, Kovalska M, Chomova M, et al. Global brain ischemia in rats is associated with mitochondrial release and downregulation of Mfn2 in the cerebral cortex, but not the hippocampus. Int J Mol Med. 2019;43(6):2420-8.10.3892/ijmm.2019.4168648817131017259]Search in Google Scholar
[25. Kumar R, Bukowski MJ, Wider JM, Reynalds CA, Calo L, Bradley L, et al. Mitochondrial dynamics following global cerebral ischemia. Mol Cell Neurosci. 2016;76:68-75.10.1016/j.mcn.2016.08.010505682927567688]Search in Google Scholar
[26. Rouslin W, Long I, Richard B, Broge CW. Why are ATP depletion rates in situ in ischemic myocardium so much lower than one might predict from the activity of the mitochondrial ATPase in sonicated heart mitochondria? J Mol Cell Cardiol. 1997;29:1505-10.]Search in Google Scholar
[27. Kuznetsov AV, Javadov S, Margreiter R, Grimm M, Hagenbuchner J, Ausserlechner MJ. The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury. Antiox. 2019;8(10):454.10.3390/antiox8100454682666331590423]Search in Google Scholar
[28. Deroche-Gamonet V, Revest JM, Fiancette JF, Balado E, Koehl M, Grosjean N, et.al. Depleting adult dentate gyrus neurogenesis increases cocaine-seeking behavior. Mol Psych. 2019;24(2): 312-20.10.1038/s41380-018-0038-029507372]Search in Google Scholar
[29. Оyedotun KS, Lemire BD. The quaternary structure of the Saccharomyces cerevisiae succinate dehydrogenase. Homology modeling, cofactor docking, and molecular dynamics simulation studies. J Biol Chem. 2004;279(10):9424-1.]Search in Google Scholar
[30. Sotler R, Poljšak B, Dahmane R, Jukić T, Pavan Jukić D, Rotim C, Trebše P, Starc A. Prooxidant activities of antioxidants and their impact on health. Acta Clin Croat. 2019; 58(4):726-36.10.20471/acc.2019.58.04.20731429832595258]Search in Google Scholar
[31. Palagina IA. Pro-/antioxidant reactions and nitrogen oxide metabolism under sub-chronic effect of succinic acid derivatives. The Ukrainian Biochemical Journal. 2017;89(4):22-33.10.15407/ubj89.04.022]Search in Google Scholar
[32. Hurst S, Hoek J, Sheu SS. Mitochondrial Ca2+ and regulation of the permeability transition pore. J Bioenerg Biomembr. 2017;49(1):27-47.10.1007/s10863-016-9672-x539327327497945]Search in Google Scholar
[33. Panneer Selvam S, Roth BM, Nganga R, Kim J, Cooley MA, Helke K, et al. Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. J Biol Chem. 2018;293(25):9784-800.10.1074/jbc.RA118.003506601645329748384]Search in Google Scholar
[34. Milasta S, Dillon CP, Sturm OE, Verbist KC, Brewer TL, Quarato G, et al. Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function. Immun. 2016;44(1):88-102.10.1016/j.immuni.2015.12.002493648726795252]Search in Google Scholar
[35. Radak D, Katsiki N, Resanovic I, Jovanovic A, Sudar-Milovanovic E, Zafirovic S, et al. Apoptosis and Acute Brain Ischemia in Ischemic Stroke. Curr Vasc Pharmacol. 2017;15(2):115-22.10.2174/157016111566616110409552227823556]Search in Google Scholar