MRI reduces variation of contouring for boost clinical target volume in breast cancer patients without surgical clips in the tumour bed
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17 mars 2017
À propos de cet article
Catégorie d'article: Research Articles
Publié en ligne: 17 mars 2017
Pages: 160 - 168
Reçu: 05 déc. 2016
Accepté: 19 févr. 2017
DOI: https://doi.org/10.1515/raon-2017-0014
Mots clés
© 2017 Noora Al-Hammadi, Palmira Caparrotti, Saju Divakar, Mohamed Riyas, Suparna Halsnad Chandramouli, Rabih Hammoud, Jillian Hayes, Maeve Mc Garry, Satheesh Prasad Paloor, Primoz Petric
This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Accuracy index (AI) and inter-delineation distances (IDD), based on the expert consensus (EC) delineation as the reference_ The differences in AI and IDD between CT and MRI were statistically significant (p < 0_05)
| CT | MRI | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | ||||||||||||
| IDD [mm] | AI | IDD [mm] | AI | |||||||||
| 2.1 | 0.8 | 38 | 0.88 | 0.02 | 3 | 1.8 | 0.58 | 32 | 0.88 | 0.01 | 2 | |
| 3.6 | 1.9 | 53 | 0.78 | 0.1 | 12 | 3.2 | 1.9 | 59 | 0.83 | 0.02 | 3 | |
| 3.9 | 2.6 | 67 | 0.67 | 0.07 | 10 | 3.2 | 1.8 | 56 | 0.78 | 0.02 | 2 | |
| 2.3 | 1 | 43 | 0.75 | 0.06 | 8 | 2.3 | 0.9 | 39 | 0.77 | 0.05 | 6 | |
| 6 | 4 | 67 | 0.61 | 0.15 | 24 | 4.5 | 2.1 | 47 | 0.73 | 0.14 | 20 | |
| 2.6 | 1.1 | 42 | 0.82 | 0.02 | 2 | 2.6 | 1 | 38 | 0.83 | 0.02 | 2 | |
| 6 | 4.1 | 68 | 0.64 | 0.09 | 14 | 3.6 | 1.8 | 50 | 0.76 | 0.05 | 7 | |
| 2.4 | 1.2 | 50 | 0.85 | 0.02 | 2 | 2.2 | 1 | 45 | 0.86 | 0.04 | 4 | |
| 3 | 2.9 | 97 | 0.81 | 0.04 | 5 | 2.9 | 1.8 | 62 | 0.80 | 0.05 | 6 | |
| 4.5 | 3.5 | 78 | 0.77 | 0.07 | 9 | 3.3 | 2 | 61 | 0.84 | 0.02 | 2 | |
| 3.3 | 2 | 61 | 0.74 | 0.09 | 12 | 2.5 | 1.3 | 52 | 0.83 | 0.02 | 3 | |
| 3.4 | 2.3 | 68 | 0.77 | 0.06 | 8 | 3.6 | 1.7 | 47 | 0.80 | 0.02 | 2 | |
| 3.6 | 2.3 | 61 | 0.76 | 0.07 | 9 | 3 | 1.5 | 49 | 0.81 | 0.04 | 5 | |
Results for inter-observer variation in contouring_ The difference in mean generalized conformity index (CIgen) between the CT and MRI based contouring was statistically significant (p = 0_007)
| Case | CT | MRI | ||||
|---|---|---|---|---|---|---|
| 198 (10) | 5 | 0.85 | 106 (4) | 4 | 0.87 | |
| 241 (37.5) | 16 | 0.69 | 256 (28) | 11 | 0.77 | |
| 108 (20.7) | 19 | 0.56 | 125 (10) | 8 | 0.75 | |
| 75 (18.1) | 24 | 0.64 | 92 (12) | 13 | 0.69 | |
| 175 (47.9) | 27 | 0.46 | 217 (68) | 31 | 0.63 | |
| 140 (10.1) | 7 | 0.76 | 125 (14) | 11 | 0.76 | |
| 103(39.7) | 39 | 0.48 | 64 (2) | 4 | 0.66 | |
| 180 (22.5) | 12 | 0.79 | 158 (14) | 9 | 0.8 | |
| 135 (19.8) | 15 | 0.77 | 126 (20) | 16 | 0.71 | |
| 204 (44.3) | 22 | 0.68 | 215 (19) | 9 | 0.76 | |
| 99 (14.4) | 15 | 0.66 | 135 (11) | 8 | 0.79 | |
| 195 (27.3) | 14 | 0.69 | 210 (29) | 14 | 0.74 | |
| 154 (26) | 18 | 0.67 (0.12) | 152 (19) | 12 | 0.74 (0.07) | |