A Continuous–Time Markov Chain Modeling Cancer–Immune System Interactions
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19 dic 2018
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Publicado en línea: 19 dic 2018
Páginas: 106 - 118
Recibido: 01 dic 2017
Aceptado: 05 feb 2018
DOI: https://doi.org/10.2478/caim-2018-0018
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© 2018 Diletta Burini, et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
In the present paper we propose two mathematical models describing, respectively at the microscopic level and at the mesoscopic level, a system of interacting tumor cells and cells of the immune system. The microscopic model is in terms of a Markov chain defined by the generator, the mesoscopic model is developed in the framework of the kinetic theory of active particles. The main result is to prove the transition from the microscopic to mesoscopic level of description.