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A Continuous–Time Markov Chain Modeling Cancer–Immune System Interactions

Communications in Applied and Industrial Mathematics's Cover Image
Communications in Applied and Industrial Mathematics
Special Issue on Mathematical modelling for complex systems: multi-agents methods. Guest Editor: Elena De Angelis


In the present paper we propose two mathematical models describing, respectively at the microscopic level and at the mesoscopic level, a system of interacting tumor cells and cells of the immune system. The microscopic model is in terms of a Markov chain defined by the generator, the mesoscopic model is developed in the framework of the kinetic theory of active particles. The main result is to prove the transition from the microscopic to mesoscopic level of description.

Publication timeframe:
Volume Open
Journal Subjects:
Mathematics, Numerical and Computational Mathematics, Applied Mathematics