Iniciar sesión
Registrarse
Restablecer contraseña
Publicar y Distribuir
Soluciones de Publicación
Soluciones de Distribución
Temas
Publicaciones
Revistas
Libros
Actas
Editoriales
Blog
Contacto
Buscar
Carrito
EUR
USD
GBP
Español
English
Deutsch
Polski
Español
Français
Italiano
Home
Revistas
European Pharmaceutical Journal
Volumen 68 (2021): Edición 1 (January 2021)
Acceso abierto
Phospholipid bilayers in model membranes and drug delivery systems: from physics to pharmacy
D. Uhríková
D. Uhríková
| 30 jul 2021
European Pharmaceutical Journal
Volumen 68 (2021): Edición 1 (January 2021)
Acerca de este artículo
Artículo anterior
Artículo siguiente
Resumen
Artículo
Figuras y tablas
Referencias
Autores
Artículos en este número
Vista previa
PDF
Cite
Compartir
Article Category:
Special Issue Article
Publicado en línea:
30 jul 2021
Páginas:
66 - 71
Recibido:
16 jun 2021
Aceptado:
17 jun 2021
DOI:
https://doi.org/10.2478/afpuc-2021-0008
Palabras clave
lipid bilayer
,
non-lamellar phases
,
antimicrobial peptides
,
lipoplexes
,
pulmonary surfactant
© 2021 D. Uhríková, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Figure 1
Lyotropic liquid crystalline mesophases: (A) multilamellar vesicles; (B) inverted hexagonal phase; (C) cubic phase of Pn3m space group.
Figure 2
(A) SANS curves of POPE/POPG vesicles; (B) CAM–POPE/POPG at P:L = 1:10 mol/mol (POPE/POPG = 3:1 mol/mol). Full lines represent fitting curves.
Figure 3
Multilamellar CAM–POPE/POPG structure identified at liquid crystalline state of the lipids (36 °C). d – repeat distance.
Figure 4
SAXS pattern of a mixture of LFchimera and DMPC/DMPG at P:L = 1:21 mol/mol (t = 24 °C). Peaks of detected cubic phases Pn3m (black) and Im3m (blue) are assigned to spacing √(h2 + k2 + l2), where h, k and l are Miller indices. Models of cubic phases of Pn3m and Im3m space group.
Figure 5
SAXS patterns of DNA–CnNO/DOPE complexes (n = 8, 10, 16 and 18) prepared at CnNO/DOPE = 0.4 mol/mol in aqueous solutions at acidic and neutral/slightly alkaline conditions, respectively. Transfection efficiency of CnNO/DOPE (n = 8–18) complexes tested on U2OS cells.
Figure 6
(A) Schematic representation of pulmonary surfactant; (B) SAXS pattern of modified porcine surfactant, surfactant incubated with 10% of LPS for 2 hours and surfactant/LPS 10% with addition of 2% of PxB (at 37 °C).