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More than 85% yield of (<italic>E</italic>)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na2HPO4) catalyzed ultrasound assisted aldol condensation of 1,2-diphenylethanone and various substituted benzaldehydes. Synthesized (<italic>E</italic>)-1,2,3-triphenylprop-2-en-1-ones were examined by their spectroscopic data, yield, micro analysis and physical constants. The effect of solvent on the yield was investigated. The pharmacological effects such as antibacterial and antifungal activities of synthesized enones were evaluated with Bauer-Kirby disc diffusion method.
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More than 85% yield of (E)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na2HPO4) catalyzed ultrasound assisted aldol condensation of 1,2-diphenylethanone and various substituted benzaldehydes. Synthesized (E)-1,2,3-triphenylprop-2-en-1-ones were examined by their spectroscopic data, yield, micro analysis and physical constants. The effect of solvent on the yield was investigated. The pharmacological effects such as antibacterial and antifungal activities of synthesized enones were evaluated with Bauer-Kirby disc diffusion method.

Ultrasound assisted synthesis and pharmacological evaluation of some (<italic>E</italic>)-1,2,3-triphenylprop-2-en-1-ones

Postgraduate and Research Department of Chemistry

Ovidius University Annals of Chemistry

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Ultrasound assisted synthesis and pharmacological evaluation of some ()-1,2,3-triphenylprop-2-en-1-ones

More than 85% yield of (E)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na2HPO4) catalyzed ultrasound assisted aldol...

Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones

Online veröffentlicht: 21. Dez. 2020

Seitenbereich: 152 - 157

Eingereicht: 08. Juli 2020

Akzeptiert: 21. Nov. 2020

DOI: https://doi.org/10.2478/auoc-2020-0024

Schlüsselwörter
triphenyl enones, ultrasonication, disodium hydrogen phosphate, aldol condensation, solvent effect, antimicrobial activity

© 2020 Veerendiran Mala et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones

Online veröffentlicht: 21. Dez. 2020

Seitenbereich: 152 - 157

Eingereicht: 08. Juli 2020

Akzeptiert: 21. Nov. 2020

DOI: https://doi.org/10.2478/auoc-2020-0024

Schlüsselwörtertriphenyl enones, ultrasonication, disodium hydrogen phosphate, aldol condensation, solvent effect, antimicrobial activity

© 2020 Veerendiran Mala et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
triphenyl enones, ultrasonication, disodium hydrogen phosphate, aldol condensation, solvent effect, antimicrobial activity