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More than 85% yield of (<italic>E</italic>)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na2HPO4) catalyzed ultrasound assisted aldol condensation of 1,2-diphenylethanone and various substituted benzaldehydes. Synthesized (<italic>E</italic>)-1,2,3-triphenylprop-2-en-1-ones were examined by their spectroscopic data, yield, micro analysis and physical constants. The effect of solvent on the yield was investigated. The pharmacological effects such as antibacterial and antifungal activities of synthesized enones were evaluated with Bauer-Kirby disc diffusion method.
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More than 85% yield of (E)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na2HPO4) catalyzed ultrasound assisted aldol condensation of 1,2-diphenylethanone and various substituted benzaldehydes. Synthesized (E)-1,2,3-triphenylprop-2-en-1-ones were examined by their spectroscopic data, yield, micro analysis and physical constants. The effect of solvent on the yield was investigated. The pharmacological effects such as antibacterial and antifungal activities of synthesized enones were evaluated with Bauer-Kirby disc diffusion method.

Ultrasound assisted synthesis and pharmacological evaluation of some (<italic>E</italic>)-1,2,3-triphenylprop-2-en-1-ones

Postgraduate and Research Department of Chemistry

Ovidius University Annals of Chemistry

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Ultrasound assisted synthesis and pharmacological evaluation of some ()-1,2,3-triphenylprop-2-en-1-ones

More than 85% yield of (E)-1,2,3-triphenylprop-2-en-1-ones were synthesized using disodium hydrogen phosphate (Na2HPO4) catalyzed ultrasound assisted aldol...

Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones

Publié en ligne: 21 déc. 2020

Pages: 152 - 157

Reçu: 08 juil. 2020

Accepté: 21 nov. 2020

DOI: https://doi.org/10.2478/auoc-2020-0024

Mots clés
triphenyl enones, ultrasonication, disodium hydrogen phosphate, aldol condensation, solvent effect, antimicrobial activity

© 2020 Veerendiran Mala et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Ultrasound assisted synthesis and pharmacological evaluation of some (E)-1,2,3-triphenylprop-2-en-1-ones

Publié en ligne: 21 déc. 2020

Pages: 152 - 157

Reçu: 08 juil. 2020

Accepté: 21 nov. 2020

DOI: https://doi.org/10.2478/auoc-2020-0024

Mots cléstriphenyl enones, ultrasonication, disodium hydrogen phosphate, aldol condensation, solvent effect, antimicrobial activity

© 2020 Veerendiran Mala et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
triphenyl enones, ultrasonication, disodium hydrogen phosphate, aldol condensation, solvent effect, antimicrobial activity