This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Belouzard S., Chu V.C., Whittaker G.R.: Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites. Proc. Natl. Acad. Sci. USA, 106, 5871–5876 (2009)BelouzardS.ChuV.C.WhittakerG.R.Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites10658715876200910.1073/pnas.0809524106Search in Google Scholar
Beniac D.R., Andonov A., Grudeski E., Booth T.F.: Architecture of the SARS coronavirus prefusion spike. Nat. Struct. Mol. Biol. 13, 751‐752 (2006)BeniacD.R.AndonovA.GrudeskiE.BoothT.F.Architecture of the SARS coronavirus prefusion spike13751‐752200610.1038/nsmb1123Search in Google Scholar
Bernstein K.E., Khan Z., Giani J.F., Cao D.Y., Bernstein E.A., Shen X.Z.: Angiotensin-converting enzyme in innate and adaptive immunity. Nat. Rev. Nephrol. 14, 325–336 (2018)BernsteinK.E.KhanZ.GianiJ.F.CaoD.Y.BernsteinE.A.ShenX.Z.Angiotensin-converting enzyme in innate and adaptive immunity14325336201810.1038/nrneph.2018.15Search in Google Scholar
Boonacker E., Van Noorden C.J.: The multifunctional or moonlighting protein CD26/DPPIV. Eur. J. Cell Biol. 82, 53–73 (2003)BoonackerE.Van NoordenC.J.The multifunctional or moonlighting protein CD26/DPPIV825373200310.1078/0171-9335-00302Search in Google Scholar
Burkard C., Verheije M.H., Wicht O., van Kasteren S.I., van Kuppeveld F.J., Haagmans B.L., Pelkmans L., Rottier P.J., Bosch B.J., de Haan C.A.: Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. PLoS Pathog. 10, e1004502(2014)BurkardC.VerheijeM.H.WichtO.van KasterenS.I.van KuppeveldF.J.HaagmansB.L.PelkmansL.RottierP.J.BoschB.J.de HaanC.A.Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner10e1004502201410.1371/journal.ppat.1004502Search in Google Scholar
Cai G., Bossé Y., Xiao F., Kheradmand F., Amos CI.: Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2. Am. J. Respir. Crit. Care. Med. 201, 1557–1559 (2020)CaiG.BosséY.XiaoF.KheradmandF.AmosCI.Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-220115571559202010.1164/rccm.202003-0693LESearch in Google Scholar
Cai G.: Bulk and single-cell transcriptomics identify tobacco-use disparity in lung gene expression of ACE2, the receptor of 2019-nCov. medRxiv, DOI: 10.1101/2020.02.05.20020107 (2020)CaiG.Bulk and single-cell transcriptomics identify tobacco-use disparity in lung gene expression of ACE2, the receptor of 2019-nCov, DOI: 10.1101/2020.02.05.200201072020Open DOISearch in Google Scholar
Cao X.: COVID-19: immunopathology and its implications for therapy. Nat. Rev. Immunol. 20, 269–270 (2020)CaoX.COVID-19: immunopathology and its implications for therapy20269270202010.1038/s41577-020-0308-3Search in Google Scholar
Channappanavar R., Fehr A.R., Zheng J., Wohlford-Lenane C., Abrahante J.E., Mack M., Sompallae R., McCray P.B. Jr, Meyerholz D.K., Perlman S.: IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. J. Clin. Invest. 129, 3625–3639 (2019)ChannappanavarR.FehrA.R.ZhengJ.Wohlford-LenaneC.AbrahanteJ.E.MackM.SompallaeR.McCrayP.B.JrMeyerholzD.K.PerlmanS.IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes12936253639201910.1172/JCI126363Search in Google Scholar
Chen N., Zhang L. i wsp.: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet, 395, 507–513 (2020)ChenN.ZhangL.Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study395507513202010.1016/S0140-6736(20)30211-7Search in Google Scholar
Chen Y., Liu Q., Guo D.: Emerging coronaviruses: Genome structure, replication, and pathogenesis. J. Med. Virol. 92, 418–423 (2020)ChenY.LiuQ.GuoD.Emerging coronaviruses: Genome structure, replication, and pathogenesis92418423202010.1002/jmv.25681Search in Google Scholar
Cheng J., Zhao Y., Xu G., Zhang K., Jia W., Sun Y., Zhao J., Xue J., Hu Y., Zhang G.: The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism. Viruses, 11, 972 (2019)ChengJ.ZhaoY.XuG.ZhangK.JiaW.SunY.ZhaoJ.XueJ.HuY.ZhangG.The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism11972201910.3390/v11100972Search in Google Scholar
Cheng Z., Yuen K.Y. i wsp.: Identification of TMPRSS2 as a susceptibility gene for severe 2009 pandemic A(H1N1) influenza and A(H7N9) influenza. J. Infect. Dis. 212, 1214–1221 (2015)ChengZ.YuenK.Y.Identification of TMPRSS2 as a susceptibility gene for severe 2009 pandemic A(H1N1) influenza and A(H7N9) influenza21212141221201510.1093/infdis/jiv246Search in Google Scholar
Chiu R.W., Lo Y.M. i wsp.: ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndrome. Clin. Chem. 50, 1683–1686 (2004)ChiuR.W.LoY.M.ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndrome5016831686200410.1373/clinchem.2004.035436Search in Google Scholar
Chu H., Yuen K.Y. i wsp.: Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19. Clin. Infect. Dis. 71, 1400–1409 (2020)ChuH.YuenK.Y.Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-197114001409202010.1093/cid/ciaa410Search in Google Scholar
Coutard B., Valle C., de Lamballerie X., Canard B., Seidah N.G., Decroly E.: The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antiviral Res. 176, 104742 (2020)CoutardB.ValleC.de LamballerieX.CanardB.SeidahN.G.DecrolyE.The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade176104742202010.1016/j.antiviral.2020.104742Search in Google Scholar
Davanzo G.G., Farias A.S. i wsp.: SARS-CoV-2 Uses CD4 to Infect T Helper Lymphocytes. medRxiv, DOI: 10.1101/2020.09.25.20200329 (2020)DavanzoG.G.FariasA.S.SARS-CoV-2 Uses CD4 to Infect T Helper Lymphocytes, DOI: 10.1101/2020.09.25.202003292020Open DOISearch in Google Scholar
de Candia P., Prattichizzo F., Garavelli S., Matarese G.: T Cells: Warriors of SARS-CoV-2 Infection. Trends Immunol. 42, 18–30 (2021)de CandiaP.PrattichizzoF.GaravelliS.MatareseG.T Cells: Warriors of SARS-CoV-2 Infection421830202110.1016/j.it.2020.11.002Search in Google Scholar
de Haan C.A., Rottier P.J.: Molecular interactions in the assembly of coronaviruses. Adv. Virus Res. 64, 165–230 (2005)de HaanC.A.RottierP.J.Molecular interactions in the assembly of coronaviruses64165230200510.1016/S0065-3527(05)64006-7Search in Google Scholar
de Wilde A.H., Snijder E.J., Kikkert M., van Hemert M.J.: Host Factors in Coronavirus Replication. Curr. Top. Microbiol. Immunol. 419, 1–42 (2018)de WildeA.H.SnijderE.J.KikkertM.van HemertM.J.Host Factors in Coronavirus Replication419142201810.1007/82_2017_25711998028643204Search in Google Scholar
Diao B., Chen Y. i wsp.: Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19). Front. Immunol. 11, 827 (2020)DiaoB.ChenY.Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)11827202010.3389/fimmu.2020.00827720590332425950Search in Google Scholar
Du L., Zhou Y. i wsp.: A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein. J. Virol. 88, 704570–704553 (2014)DuL.ZhouY.A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein88704570704553201410.1128/JVI.00433-14405435524719424Search in Google Scholar
Duan K., Yang X. i wsp.: Effectiveness of convalescent plasma therapy in severe COVID-19 patients. Proc. Natl. Acad. Sci. USA, 117, 9490–9496 (2020)DuanK.YangX.Effectiveness of convalescent plasma therapy in severe COVID-19 patients11794909496202010.1073/pnas.2004168117719683732253318Search in Google Scholar
Fehr A.R., Perlman S.: Coronaviruses: an overview of their replication and pathogenesis. Methods Mol. Biol. 1282, 1–23 (2015)FehrA.R.PerlmanS.Coronaviruses: an overview of their replication and pathogenesis1282123201510.1007/978-1-4939-2438-7_1436938525720466Search in Google Scholar
Feng Z., Chen Y. i wsp.: The Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Directly Decimates Human Spleens and Lymph Nodes. medRxiv, DOI: 10.1101/2020.03.27.20045427 (2020)FengZ.ChenY.The Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Directly Decimates Human Spleens and Lymph Nodes, DOI: 10.1101/2020.03.27.200454272020Open DOISearch in Google Scholar
Forni D., Cagliani R., Clerici M.: Molecular Evolution of Human Coronavirus Genomes. Trends Microbiol. 25, 35–48 (2017)ForniD.CaglianiR.ClericiM.Molecular Evolution of Human Coronavirus Genomes253548201710.1016/j.tim.2016.09.001711121827743750Search in Google Scholar
Fu J., Zhou B., Zhang L., Balaji K.S., Wei C., Liu X., Chen H., Peng J., Fu J.: Expressions and significances of the angiotensin--converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19. Mol. Biol. Rep. 47, 4383–4392 (2020)FuJ.ZhouB.ZhangL.BalajiK.S.WeiC.LiuX.ChenH.PengJ.FuJ.Expressions and significances of the angiotensin--converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-194743834392202010.1007/s11033-020-05478-4722435132410141Search in Google Scholar
Galloway S.E., Dugan V.G. i wsp.: Emergence of SARS-CoV-2 B.1.1.7 Lineage – United States, December 29, 2020-January 12, 2021. MMWR Morb. Mortal. Wkly. Rep. 70, 95–99 (2021)GallowayS.E.DuganV.G.Emergence of SARS-CoV-2 B.1.1.7 Lineage – United States, December 29, 2020-January 12, 2021709599202110.15585/mmwr.mm7003e2782177233476315Search in Google Scholar
Gao Q., Qin C. i wsp.: Development of an inactivated vaccine candidate for SARS-CoV-2. Science, 369, 77–81 (2020)GaoQ.QinC.Development of an inactivated vaccine candidate for SARS-CoV-23697781202010.1126/science.abc1932720268632376603Search in Google Scholar
Giamarellos-Bourboulis E.J., Koutsoukou A. i wsp.: Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure. Cell Host Microbe, 27, 992–1000 (2020)Giamarellos-BourboulisE.J.KoutsoukouA.Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure279921000202010.1016/j.chom.2020.04.009717284132320677Search in Google Scholar
Glowacka I., Pöhlmann S. i wsp.: Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63. J. Virol. 84, 1198–1205 (2010)GlowackaI.PöhlmannS.Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL638411981205201010.1128/JVI.01248-09Search in Google Scholar
Glowacka I., Pöhlmann S. i wsp.: Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response. J. Virol. 85, 4122–4134 (2011)GlowackaI.PöhlmannS.Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response8541224134201110.1128/JVI.02232-10Search in Google Scholar
Gorbalenya A.E., Enjuanes L., Ziebuhr J., Snijder EJ.: Nidovirales: evolving the largest RNA virus genome. Virus Res. 117, 17–37 (2006)GorbalenyaA.E.EnjuanesL.ZiebuhrJ.SnijderEJ.Nidovirales: evolving the largest RNA virus genome1171737200610.1016/j.virusres.2006.01.017Search in Google Scholar
Gralinski L.E., Menachery V.D.: Return of the Coronavirus: 2019-nCoV. Viruses, 12, 135 (2020)GralinskiL.E.MenacheryV.D.Return of the Coronavirus: 2019-nCoV12135202010.3390/v12020135Search in Google Scholar
Guan W.J., Zhong N.S. i wsp.: China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N. Engl. J. Med. 382, 1708–1720 (2020)GuanW.J.ZhongN.S.China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China38217081720202010.1056/NEJMoa2002032Search in Google Scholar
Heald-Sargent T., Gallagher T.: Ready, set, fuse! The coronavirus spike protein and acquisition of fusion competence. Viruses, 4, 557–580 (2012)Heald-SargentT.GallagherT.Ready, set, fuse! The coronavirus spike protein and acquisition of fusion competence4557580201210.3390/v4040557Search in Google Scholar
Hindson J.: COVID-19: faecal-oral transmission? Nat. Rev. Gastroenterol. Hepatol. 17, 259 (2020)HindsonJ.COVID-19: faecal-oral transmission?17259202010.1038/s41575-020-0295-7Search in Google Scholar
Hoffmann M., Hofmann-Winkler H., Pöhlmann S.: Priming Time: How Cellular Proteases Arm Coronavirus Spike Proteins (w) Activation of Viruses by Host Proteases, red. Böttcher-Friebertshäuser E., Garten W., Klenk H.D, Springer International Publishing AG, part of Springer Nature, 2018, s. 71–98HoffmannM.Hofmann-WinklerH.PöhlmannS.Böttcher-FriebertshäuserE.GartenW.KlenkH.DSpringer International Publishing AG, part of Springer Nature2018, s. 719810.1007/978-3-319-75474-1_4Search in Google Scholar
Hoffmann M., Pöhlmann S. i wsp.: SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell, 181, 271–280 (2020)HoffmannM.PöhlmannS.SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor181271280202010.1016/j.cell.2020.02.052Search in Google Scholar
Huang C., Cao B. i wsp.: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet, 395, 497–506 (2020)HuangC.CaoB.Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China395497506202010.1016/S0140-6736(20)30183-5Search in Google Scholar
Huang I.C., Farzan M. i wsp.: Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 7, e1001258 (2011)HuangI.C.FarzanM.Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus7e1001258201110.1371/journal.ppat.1001258301712121253575Search in Google Scholar
Hulswit R.J.G., de Haan C.A.M., Bosch B.-J.: Coronavirus Spike Protein and Tropism Changes. Adv. Virus Res. 96, 29–57 (2016)HulswitR.J.G.de HaanC.A.M.BoschB.-J.Coronavirus Spike Protein and Tropism Changes962957201610.1016/bs.aivir.2016.08.004711227727712627Search in Google Scholar
Hussain M., Jabeen N., Raza F., Shabbir S., Baig A.A., Amanullah A., Aziz B.: Structural variations in human ACE2 may influence its binding with SARS-CoV-2 spike protein. J. Med. Virol. 92, 1580–1586 (2020)HussainM.JabeenN.RazaF.ShabbirS.BaigA.A.AmanullahA.AzizB.Structural variations in human ACE2 may influence its binding with SARS-CoV-2 spike protein9215801586202010.1002/jmv.25832722837232249956Search in Google Scholar
Imai Y., Kuba K., Ohto-Nakanishi T., Penninger JM.: Angiotensin-converting enzyme 2 (ACE2) in disease pathogenesis. Circ. J. 74, 405–410 (2010)ImaiY.KubaK.Ohto-NakanishiT.PenningerJM.Angiotensin-converting enzyme 2 (ACE2) in disease pathogenesis74405410201010.1253/circj.CJ-10-004520134095Search in Google Scholar
Imai Y., Penninger J.M. i wsp.: Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature, 436, 112–116 (2005)ImaiY.PenningerJ.M.Angiotensin-converting enzyme 2 protects from severe acute lung failure436112116200510.1038/nature03712709499816001071Search in Google Scholar
International Committee on Taxonomy of Viruses. https://talk.ictvonline.orgxs (17.02.2021)https://talk.ictvonline.orgxs (17.02.2021)Search in Google Scholar
Israelow B., Iwasaki A. i wsp.: Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling. J. Exp. Med. 217, e20201241 (2020)IsraelowB.IwasakiA.Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling217e20201241202010.1084/jem.20201241740102532750141Search in Google Scholar
Itoyama S., Sasazuki T. i wsp.: Identification of an alternative 5’-untranslated exon and new polymorphisms of angiotensin--converting enzyme 2 gene: lack of association with SARS in the Vietnamese population. Am. J. Med. Genet. A, 136, 52–57 (2005)ItoyamaS.SasazukiT.Identification of an alternative 5’-untranslated exon and new polymorphisms of angiotensin--converting enzyme 2 gene: lack of association with SARS in the Vietnamese population1365257200510.1002/ajmg.a.30779713809715937940Search in Google Scholar
Karczewski K.J., MacArthur D.G. i wsp.: The mutational constraint spectrum quantified from variation in 141,456 humans. Nature, 581, 434–443 (2020)KarczewskiK.J.MacArthurD.G.The mutational constraint spectrum quantified from variation in 141,456 humans581434443202010.1038/s41586-020-2308-7733419732461654Search in Google Scholar
Kaur S.P., Gupta V.: COVID-19 Vaccine: A comprehensive status report. Virus Res. 288, 198114 (2020)KaurS.P.GuptaV.COVID-19 Vaccine: A comprehensive status report288198114202010.1016/j.virusres.2020.198114742351032800805Search in Google Scholar
Khalaf K., Papp N., Chou J.T., Hana D., Mackiewicz A., Kaczmarek M.: SARS-CoV-2: Pathogenesis, and Advancements in Diagnostics and Treatment. Front. Immunol. 11, 570927 (2020)KhalafK.PappN.ChouJ.T.HanaD.MackiewiczA.KaczmarekM.SARS-CoV-2: Pathogenesis, and Advancements in Diagnostics and Treatment11570927202010.3389/fimmu.2020.570927757310133123144Search in Google Scholar
Kleine-Weber H., Schroeder S., Krüger N., Prokscha A., Naim H.Y., Müller M.A., Drosten C., Pöhlmann S., Hoffmann M.: Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus. Emerg. Microbes Infect. 9, 155–168 (2020)Kleine-WeberH.SchroederS.KrügerN.ProkschaA.NaimH.Y.MüllerM.A.DrostenC.PöhlmannS.HoffmannM.Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus9155168202010.1080/22221751.2020.1713705700667531964246Search in Google Scholar
Korber B., Montefiori D.C. i wsp.: Tracking Changes in SARS--CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus. Cell, 182, 812–827 (2020)KorberB.MontefioriD.C.Tracking Changes in SARS--CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus182812827202010.1016/j.cell.2020.06.043733243932697968Search in Google Scholar
Krammer F.: SARS-CoV-2 vaccines in development. Nature, 586, 516–527 (2020)KrammerF.SARS-CoV-2 vaccines in development586516527202010.1038/s41586-020-2798-332967006Search in Google Scholar
Kuba K., Imai Y., Ohto-Nakanishi T., Penninger J.M.: Trilogy of ACE2: a peptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters. Pharmacol. Ther. 128, 119–128 (2010)KubaK.ImaiY.Ohto-NakanishiT.PenningerJ.M.Trilogy of ACE2: a peptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters128119128201010.1016/j.pharmthera.2010.06.003711267820599443Search in Google Scholar
Kuba K., Penninger J.M. i wsp.: A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat. Med. 11, 875–879 (2005)KubaK.PenningerJ.M.A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury11875879200510.1038/nm1267709578316007097Search in Google Scholar
Lauer S.A., Grantz K.H., Bi Q., Jones F.K., Zheng Q., Meredith H.R., Azman A.S., Reich N.G., Lessler J.: The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application. Ann. Intern. Med. 172, 577–582 (2020)LauerS.A.GrantzK.H.BiQ.JonesF.K.ZhengQ.MeredithH.R.AzmanA.S.ReichN.G.LesslerJ.The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application172577582202010.7326/M20-0504708117232150748Search in Google Scholar
Leung K., Shum M.H., Leung G.M., Lam T.T., Wu J.T.: Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020. Euro. Surveill. 26, 2002106 (2021)LeungK.ShumM.H.LeungG.M.LamT.T.WuJ.T.Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020262002106202110.2807/1560-7917.ES.2020.26.1.2002106779160233413740Search in Google Scholar
Li D., Chen Y., Liu H., Jia Y., Li F., Wang W., Wu J., Wan Z., Cao Y., Zeng R.: Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS--COVID-19 study. Signal Transduct. Target Ther. 5, 62 (2020)LiD.ChenY.LiuH.JiaY.LiF.WangW.WuJ.WanZ.CaoY.ZengR.Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS--COVID-19 study562202010.1038/s41392-020-0163-5719884432371949Search in Google Scholar
Li F.: Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections. J. Virol. 82, 6984–6991 (2008)LiF.Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections8269846991200810.1128/JVI.00442-08244698618448527Search in Google Scholar
Li G., Fan Y., Lai Y., Han T., Li Z., Zhou P., Pan P., Wang W., Hu D., Liu X., Zhang Q., Wu J.: Coronavirus infections and immune responses. J. Med. Virol. 92, 424–432 (2020)LiG.FanY.LaiY.HanT.LiZ.ZhouP.PanP.WangW.HuD.LiuX.ZhangQ.WuJ.Coronavirus infections and immune responses92424432202010.1002/jmv.25685716654731981224Search in Google Scholar
Li J., Liang Q. i wsp.: Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS--CoV-2 Pathogenesis. Med. 2, 99–112 (2021)LiJ.LiangQ.Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS--CoV-2 Pathogenesis299112202110.1016/j.medj.2020.07.002737304832838362Search in Google Scholar
Li X., Zhang W. i wsp.: Immune characteristics distinguish patients with severe disease associated with SARS-CoV-2. Immunol Res. 68, 398–404 (2020)LiX.ZhangW.Immune characteristics distinguish patients with severe disease associated with SARS-CoV-268398404202010.1007/s12026-020-09156-2752186432989677Search in Google Scholar
Lim Y.X., Ng Y.L., Tam J.P., Liu D.X.: Human Coronaviruses: A Review of Virus-Host Interactions. Diseases, 4, 26 (2016)LimY.X.NgY.L.TamJ.P.LiuD.X.Human Coronaviruses: A Review of Virus-Host Interactions426201610.3390/diseases4030026545628528933406Search in Google Scholar
Liu L., Chen Z. i wsp.: Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS--CoV infection. JCI Insight, 4, e123158 (2019)LiuL.ChenZ.Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS--CoV infection4e123158201910.1172/jci.insight.123158647843630830861Search in Google Scholar
Long Q.X., Huang A.L. i wsp.: Antibody responses to SARS--CoV-2 in patients with COVID-19. Nat. Med. 26, 845–848 (2020)LongQ.X.HuangA.L.Antibody responses to SARS--CoV-2 in patients with COVID-1926845848202010.1038/s41591-020-0897-132350462Search in Google Scholar
Lu G., Gao G.F. i wsp.: Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature, 500, 227–231 (2013)LuG.GaoG.F.Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26500227231201310.1038/nature12328709534123831647Search in Google Scholar
Nal B.: Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E. J. Gen. Virol. 86, 1423‐1434 (2005)NalB.Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E861423‐1434200510.1099/vir.0.80671-015831954Search in Google Scholar
Narayanan K., Ramirez S.I., Lokugamage K.G., Makino S.: Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression. Virus Res. 202, 89–100 (2015)NarayananK.RamirezS.I.LokugamageK.G.MakinoS.Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression20289100201510.1016/j.virusres.2014.11.019444439925432065Search in Google Scholar
Neuman B.W., Buchmeier M.J. i wsp.: A structural analysis of M protein in coronavirus assembly and morphology. J. Struct. Biol. 174, 11‐22 (2011)NeumanB.W.BuchmeierM.J.A structural analysis of M protein in coronavirus assembly and morphology17411‐22201110.1016/j.jsb.2010.11.021448606121130884Search in Google Scholar
Neuman B.W., Buchmeier M.J.: Supramolecular Architecture of the Coronavirus Particle. Adv. Virus Res. 96, 1–27 (2016)NeumanB.W.BuchmeierM.J.Supramolecular Architecture of the Coronavirus Particle96127201610.1016/bs.aivir.2016.08.005711236527712621Search in Google Scholar
Park J.E., Li K., Barlan A., Fehr A.R., Perlman S., McCray P.B. Jr, Gallagher T.: Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism. Proc. Natl. Acad. Sci. USA, 113, 12262–12267 (2016)ParkJ.E.LiK.BarlanA.FehrA.R.PerlmanS.McCrayP.B.JrGallagherT.Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism1131226212267201610.1073/pnas.1608147113508699027791014Search in Google Scholar
Perlman S., Dandekar A.A.: Immunopathogenesis of coronavirus infections: implications for SARS. Nat. Rev. Immunol. 5, 917–927 (2005)PerlmanS.DandekarA.A.Immunopathogenesis of coronavirus infections: implications for SARS5917927200510.1038/nri1732709732616322745Search in Google Scholar
Qin C., Tian D.S. i wsp.: Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China. Clin. Infect. Dis. 71, 62–768 (2020)QinC.TianD.S.Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China7162768202010.1093/cid/ciaa248710812532161940Search in Google Scholar
Raj V.S., Haagmans B.L. i wsp.: Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature, 495, 251–254 (2013)RajV.S.HaagmansB.L.Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC495251254201310.1038/nature12005709532623486063Search in Google Scholar
Samad A., Ahammad F., Nain Z., Alam R., Imon R.R., Hasan M., Rahman M.S.: Designing a multi-epitope vaccine against SARS--CoV-2: an immunoinformatics approach. J. Biomol. Struct. Dyn. 1–17 (2020)SamadA.AhammadF.NainZ.AlamR.ImonR.R.HasanM.RahmanM.S.Designing a multi-epitope vaccine against SARS--CoV-2: an immunoinformatics approach117202010.1080/07391102.2020.1792347744180532677533Search in Google Scholar
Sawicki S.G., Sawicki D.L., Siddell S.G.: A contemporary view of coronavirus transcription. J. Virol. 81, 20–29 (2007)SawickiS.G.SawickiD.L.SiddellS.G.A contemporary view of coronavirus transcription812029200710.1128/JVI.01358-06179724316928755Search in Google Scholar
Seys L.J.M., Widagdo W., Verhamme F.M., Kleinjan A., Janssens W., Joos G.F., Bracke K.R., Haagmans B.L., Brusselle G.G.: DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients. Clin. Infect. Dis. 66, 45–53 (2018)SeysL.J.M.WidagdoW.VerhammeF.M.KleinjanA.JanssensW.JoosG.F.BrackeK.R.HaagmansB.L.BrusselleG.G.DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease Patients664553201810.1093/cid/cix741710810029020176Search in Google Scholar
Smith J.C., Sausville E.L., Girish V., Yuan M.L., Vasudevan A., John K.M., Sheltzer J.M.: Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract. Dev. Cell, 53, 514–529 (2020)SmithJ.C.SausvilleE.L.GirishV.YuanM.L.VasudevanA.JohnK.M.SheltzerJ.M.Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract53514529202010.1016/j.devcel.2020.05.012722991532425701Search in Google Scholar
Snijder E.J., Decroly E., Ziebuhr J.: The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing. Adv. Virus Res. 96, 59–126 (2016)SnijderE.J.DecrolyE.ZiebuhrJ.The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing9659126201610.1016/bs.aivir.2016.08.008711228627712628Search in Google Scholar
Stopsack K.H., Mucci L.A., Antonarakis E.S., Nelson P.S., Kantoff P.W.: TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention? Cancer Discov. 10, 779–782 (2020)StopsackK.H.MucciL.A.AntonarakisE.S.NelsonP.S.KantoffP.W.TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention?10779782202010.1158/2159-8290.CD-20-0451743747232276929Search in Google Scholar
Su S., Wong G., Shi W.: Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses. Trends Microbiol. 24, 490–502 (2016)SuS.WongG.ShiW.Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses24490502201610.1016/j.tim.2016.03.003712551127012512Search in Google Scholar
Tan L., Wang Q., Zhang D., Ding J., Huang Q., Tang Y.Q., Wang Q., Miao H.: Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study. Signal Transduct. Target Ther. 5, 33 (2020)TanL.WangQ.ZhangD.DingJ.HuangQ.TangY.Q.WangQ.MiaoH.Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study533202010.1038/s41392-020-0148-4710041932296069Search in Google Scholar
Terada Y., Matsui N., Noguchi K., Kuwata R., Shimoda H., Soma T., Mochizuki M., Maeda K.: Emergence of pathogenic coronaviruses in cats by homologous recombination between feline and canine coronaviruses. PLoS One, 9, e106534 (2014)TeradaY.MatsuiN.NoguchiK.KuwataR.ShimodaH.SomaT.MochizukiM.MaedaK.Emergence of pathogenic coronaviruses in cats by homologous recombination between feline and canine coronaviruses9e106534201410.1371/journal.pone.0106534415229225180686Search in Google Scholar
Tseng C.T., Sbrana E., Iwata-Yoshikawa N., Newman P.C., Garron T., Atmar R.L., Peters C.J., Couch R.B.: Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus. PLoS One, 7, e35421 (2012)TsengC.T.SbranaE.Iwata-YoshikawaN.NewmanP.C.GarronT.AtmarR.L.PetersC.J.CouchR.B.Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus7e35421201210.1371/journal.pone.0035421333506022536382Search in Google Scholar
Volz E., Ferguson N.M. i wsp.: Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: Insights from linking epidemiological and genetic data. medRxiv, 2020.12.30, 20249034VolzE.FergusonN.M.Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: Insights from linking epidemiological and genetic data202012302024903410.1101/2020.12.30.20249034Search in Google Scholar
Walls A.C., Park Y.J., Tortorici M.A., Wall A., McGuire A.T., Veesler D.: Structure, Function, and Antigenicity of the SARS--CoV-2 Spike Glycoprotein. Cell, 181, 281–292 (2020)WallsA.C.ParkY.J.TortoriciM.A.WallA.McGuireA.T.VeeslerD.Structure, Function, and Antigenicity of the SARS--CoV-2 Spike Glycoprotein181281292202010.1016/j.cell.2020.02.058710259932155444Search in Google Scholar
Wambier C.G., Goren A., Vaño-Galván S., Ramos P.M., Ossimetha A., Nau G., Herrera S., McCoy J.: Androgen sensitivity gateway to COVID-19 disease severity. Drug Dev. Res. 81, 771–776 (2020)WambierC.G.GorenA.Vaño-GalvánS.RamosP.M.OssimethaA.NauG.HerreraS.McCoyJ.Androgen sensitivity gateway to COVID-19 disease severity81771776202010.1002/ddr.21688727309532412125Search in Google Scholar
Wan Y., Li F. i wsp.: Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry. J. Virol. 94, e02015–19 (2020)WanY.LiF.Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry94e0201519202010.1128/JVI.02015-19702235131826992Search in Google Scholar
Wang N., Wang X. i wsp.: Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4. Cell Res. 23, 986–993 (2013)WangN.WangX.Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP423986993201310.1038/cr.2013.92373156923835475Search in Google Scholar
Wang Q., Liu G. i wsp.: Immunodominant SARS Coronavirus Epitopes in Humans Elicited both Enhancing and Neutralizing Effects on Infection in Non-human Primates. ACS Infect. Dis. 2, 361–376 (2016)WangQ.LiuG.Immunodominant SARS Coronavirus Epitopes in Humans Elicited both Enhancing and Neutralizing Effects on Infection in Non-human Primates2361376201610.1021/acsinfecdis.6b00006707552227627203Search in Google Scholar
WHO. Middle East respiratory syndrome coronavirus (MERS--CoV). November, 2019, http://www.who.int/emergencies/mers-cov/en/ (17.02.2021)WHONovember2019http://www.who.int/emergencies/mers-cov/en/ (17.02.2021)Search in Google Scholar
WHO. Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003. Dec 31, 2003, https://www.who.int/csr/sars/country/table2004_04_21/en/ (17.02.2021)WHODec312003https://www.who.int/csr/sars/country/table2004_04_21/en/ (17.02.2021)Search in Google Scholar
Widagdo W., Haagmans B. i wsp.: Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels. J. Virol. 90, 4838–4842 (2016)WidagdoW.HaagmansB.Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels9048384842201610.1128/JVI.02994-15Search in Google Scholar
Widagdo W., Sooksawasdi Na Ayudhya S., Hundie G.B., Haagmans B.L.: Host Determinants of MERS-CoV Transmission and Pathogenesis. Viruses, 11, 280 (2019)WidagdoW.Sooksawasdi Na AyudhyaS.HundieG.B.HaagmansB.L.Host Determinants of MERS-CoV Transmission and Pathogenesis11280201910.3390/v11030280Search in Google Scholar
Wilk A.J., Blish C.A. i wsp.: A single-cell atlas of the peripheral immune response in patients with severe COVID-19. Nat. Med. 26, 1070–1076 (2020)WilkA.J.BlishC.A.A single-cell atlas of the peripheral immune response in patients with severe COVID-192610701076202010.1038/s41591-020-0944-ySearch in Google Scholar
World Health Organization. Coronavirus disease (COVID19) Weekly Epidemiological Update. https://covid19.who.int/ (17.02.2021)World Health Organizationhttps://covid19.who.int/ (17.02.2021)Search in Google Scholar
Wrapp D., Wang N., Corbett K.S., Goldsmith J.A., Hsieh C.L., Abiona O., Graham B.S., McLellan J.S.: Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation. Science, 367, 1260–1263 (2020)WrappD.WangN.CorbettK.S.GoldsmithJ.A.HsiehC.L.AbionaO.GrahamB.S.McLellanJ.S.Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation36712601263202010.1126/science.abb2507Search in Google Scholar
Xie X., Chen J., Wang X., Zhang F., Liu Y.: Age- and gender--related difference of ACE2 expression in rat lung. Life Sci. 78, 2166–2171 (2006)XieX.ChenJ.WangX.ZhangF.LiuY.Age- and gender--related difference of ACE2 expression in rat lung7821662171200610.1016/j.lfs.2006.09.028Search in Google Scholar
Xu Z., Wang F.S. i wsp.: Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir. Med. 8, 420–422 (2020)XuZ.WangF.S.Pathological findings of COVID-19 associated with acute respiratory distress syndrome8420422202010.1016/S2213-2600(20)30076-XSearch in Google Scholar
Yang Y., Liu C., Du L., Jiang S., Shi Z., Baric R.S., Li F.: Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus. J. Virol. 89, 9119–9123 (2015)YangY.LiuC.DuL.JiangS.ShiZ.BaricR.S.LiF.Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus8991199123201510.1128/JVI.01279-15452405426063432Search in Google Scholar
Yoshimoto F.K.: The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19. Protein J. 39, 198–216 (2020)YoshimotoF.K.The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-1939198216202010.1007/s10930-020-09901-4724519132447571Search in Google Scholar
Zhang B., Zhou X., Qiu Y., Song Y., Feng F., Feng J., Song Q., Jia Q., Wang J.: Clinical characteristics of 82 cases of death from COVID-19. PLoS One, 15, e0235458 (2020)ZhangB.ZhouX.QiuY.SongY.FengF.FengJ.SongQ.JiaQ.WangJ.Clinical characteristics of 82 cases of death from COVID-1915e0235458202010.1371/journal.pone.0235458734713032645044Search in Google Scholar
Zhang L., Choe H. i wsp.: SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity. Nat. Commun. 11, 6013 (2020)ZhangL.ChoeH.SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity116013202010.1038/s41467-020-19808-4769330233243994Search in Google Scholar
Zhang L., Jackson C.B., Mou H., Ojha A., Rangarajan E.S., Izard T., Farzan M., Choe H. The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity. bioRxiv [Preprint], 2020.06.12, 148726ZhangL.JacksonC.B.MouH.OjhaA.RangarajanE.S.IzardT.FarzanM.ChoeH.The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity [Preprint], 2020.06.1214872610.1101/2020.06.12.148726Search in Google Scholar
Zhao J., Zhang Z. i wsp.: Antibody Responses to SARS-CoV-2 in Patients With Novel Coronavirus Disease 2019. Clin. Infect. Dis. 71, 2027–2034 (2020)ZhaoJ.ZhangZ.Antibody Responses to SARS-CoV-2 in Patients With Novel Coronavirus Disease 20197120272034202010.1093/cid/ciaa344Search in Google Scholar
Zhao Y., Zhao Z., Wang Y., Zhou Y., Ma Y., Zuo W.: Single-Cell RNA Expression Profiling of ACE2, the Receptor of SARS--CoV-2. Am. J. Respir. Crit. Care. Med. 202, 756–759 (2020)ZhaoY.ZhaoZ.WangY.ZhouY.MaY.ZuoW.Single-Cell RNA Expression Profiling of ACE2, the Receptor of SARS--CoV-2202756759202010.1164/rccm.202001-0179LESearch in Google Scholar
Ziegler C.G.K., Ordovas-Montanes J. i wsp.: SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell, 181, 1016–1035 (2020)ZieglerC.G.K.Ordovas-MontanesJ.SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues18110161035202010.1016/j.cell.2020.04.035Search in Google Scholar
Zumla A., Hui D.S., Perlman S.: Middle East respiratory syndrome. Lancet, 3, 60454–60458 (2015)ZumlaA.HuiD.S.PerlmanS.Middle East respiratory syndrome36045460458201510.1016/S0140-6736(15)60454-8Search in Google Scholar
Zuo Y., Knight J.S. i wsp.: Neutrophil extracellular traps in COVID-19. JCI Insight. 5, e138999 (2020)ZuoY.KnightJ.S.Neutrophil extracellular traps in COVID-195e138999202010.1172/jci.insight.138999730805732329756Search in Google Scholar