Open Access

Can Lactobacillus spp. Be a Factor Reducing the Risk of Miscarriage?

ANETA KIECKA

ANETA KIECKA

Jagiellonian University Medical College, Faculty of Health Sciences, Institute of Physiotherapy, Chair of Biomedical SciencesCracow, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
KIECKA, ANETA
, 
BARBARA MACURA

BARBARA MACURA

Jagiellonian University Medical College, Faculty of Health Sciences, Institute of Physiotherapy, Chair of Biomedical SciencesCracow, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
MACURA, BARBARA
 and 
MARIAN SZCZEPANIK

MARIAN SZCZEPANIK

Jagiellonian University Medical College, Faculty of Health Sciences, Institute of Physiotherapy, Chair of Biomedical SciencesCracow, Poland
Orcid profile
Search for this author on
Sciendo|Google Scholar
SZCZEPANIK, MARIAN
  
Dec 06, 2021
Can Lactobacillus spp. Be a Factor Reducing the Risk of Miscarriage?'s Cover Image
About this article
Previous Article
Next Article
Cite
Download Cover
Article Category: mini-review
Published Online: Dec 06, 2021
Page range: 431 - 446
Received: Sep 17, 2021
Accepted: Oct 30, 2021
DOI: https://doi.org/10.33073/pjm-2021-043
Keywords
© 2021 Monika Stasiak et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
undefined

Fig. 1.

Factors affecting the risk of miscarriage.
Factors affecting the risk of miscarriage.

Fig. 2.

Normal vaginal microbiota and vaginal dysbiosis.
Normal vaginal microbiota and vaginal dysbiosis.

Effect of vaginal microbiota on miscarriage and recurrent miscarriage_

ReferencesConclusions
MISCARRIAGENelson et al. (2007)Lack of Lactobacillus spp. in the vagina during the first trimester of pregnancy may be associated with a risk of miscarriage in the second trimester
Bretelle et al. (2015)The presence of pathogenic bacteria such as Chlamydia trachomatis, Atopobium vaginae, and Gardnella vaginalis in the vagina is associated with high-risk pregnancies and may contribute to miscarriage
Nelson et al. (2015)BV correlates with miscarriageAl-Memar et al. (2020) Decreased vaginal Lactobacillus spp. during the first or second trimester of pregnancy correlates with risk of miscarriage
Chang et al. (2020)The presence of Lactobacillus iners in the vagina increases the risk of miscarriage
Xu et al. (2020)The presence of Gardnerella, Prevotella as well as Megastrobila, and Cyclospora and the lack of Lactobacillus spp. in the vagina may contribute to pregnancy loss
RECURRENT MISCARRIAGE (RM)Llahi-Camp et al. (1996)The BV is significantly more common among women who have had a second-trimester miscarriage than among women with RM
Işik et al. (2016)The BV is associated with the occurrence of one miscarriage in the past six months. The BV does not affect the occurrence of recurrent miscarriage
Kuon et al. (2017)Lactobacillus spp. is not present in the vagina of women with RM
Zhang et al. (2019)Pathogenic bacteria in the vagina include Prevotella, Atopobium, and Streptococcus and reduced Lactobacillus spp. correlate with RM

Effect of uterine microbiota on fertility and pregnancy maintenance_

ReferencesConclusions
Kyono et al. (2018)Endometrium dominated by Lactobacillus spp. favors embryo implantation
Moreno and Simon (2018)Dysbiotic endometrium characterized by Atopobium, Bifidobacterium, Chryseobacterium, Gardnella, Haemophilus, Klebsiella, Neisseria, Staphylococcus, and Streptococcus correlates with abnormal pregnancy
Leoni et al. (2019)The presence of mixed bacterial microbiota, not always Lactobacillus spp., is associated with a normal pregnancy
Moreno et al. (2020)The endometrium before miscarriage is characterized by a greater diversity of bacteria and fewer Lactobacillus spp.
Moreno et al. (2021)Types of bacteria such as Enterococcus, Enterobacteriaceae, Streptococcus, Staphylococcus, Gardnerella, Mycoplasma, Ureaplasma, Chlamydia, and Neisseria are responsible for chronic endometritis and suspected to have adverse effects on implantation as well as may contribute to miscarriage
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Life Sciences, Microbiology and Virology
Journal RSS Feed