About this article
Article Category: Clinical Cases
Published Online: Oct 11, 2019
Page range: 75 - 81
DOI: https://doi.org/10.2478/pneum-2019-0005
Keywords
© 2019 Salmen and Strâmbu, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Figure 1
Figure 2–6
Interstitial lung diseases in children older than 2 years and teenagers
| Disorders with known causes | |
|---|---|
| Infection (8–10%) | Viral infection (eg. cytomegalovirus infection, infection with Epstein–Barr virus) |
| Bacterial infection (eg. | |
| Fungal infection (eg. infection due to | |
| Parasitic infection (eg. visceral larva migrans) | |
| Environmental conditions (13%) | Exposure to organic dusts (hypersensitivity pneumonitis [7–12%]) |
| Exposure to inorganic particulates (eg. silica, asbestos, talc, zinc) | |
| Exposure to chemical fumes, gases | |
| Drugs | Antineoplastic agents |
| Other drugs or elements (eg. penicillamine, nitrofurantoin, gold) | |
| Previous lung injuries | |
| Chronic aspiration pneumonitis (4%–5%) | |
| Resolving acute respiratory distress syndrome | |
| Bronchopulmonary dysplasia | |
| Lymphoproliferative disorders (10%) | |
| Metabolic disorders | |
| Lysosomal storage disorders (eg. Gaucher disease, Niemann–Pick disease) | |
| Degenerative disorders (eg. pulmonary microlithiasis [1%]) | |
| Immunodeficiency-associated ILD | |
| Undetermined (19–27%) | |
| Pulmonary haemorrhage syndromes | |
| Desquamative interstitial pneumonia (4–8%) | |
| Lymphocytic interstitial pneumonitis (6%) | |
| Lymphangiomatosis (4%) | |
| Nonadenoviral bronchiolitis obliterans (4%) | |
| Sarcoidosis (2%) | |
| Pulmonary alveolar proteinosis (2%) | |
| Eosinophilic syndromes (2%) | |
| Idiopathic bronchiolitis obliterans organizing pneumonia (BOOP) | |
| Bronchocentric granulomatosis (1%) | |
| Nonspecific interstitial pneumonia (correlates with ABCA3 deficiency) | |
| Acute interstitial pneumonitis | |
| Connective tissue diseases (2–4%) (juvenile rheumatoid arthritis, dermatomyositis/polymyositis, systemic sclerosis, systemic lupus erythematosus, ankylosing spondylitis, Sjögren syndrome, Behçet syndrome, mixed connective tissue disease) | |
| Autoimmune diseases (anti-glomerular basement membrane antibody disease) | |
| Pulmonary vasculitis | |
| Liver disease (chronic active hepatitis, primary biliary cirrhosis) | |
| Bowel disease (2%) (eg. ulcerative colitis, Crohn’s disease) | |
| Amyloidosis | |
| Neurocutaneous disorders (tuberous sclerosis, neurofibromatosis, ataxia–telangiectasia) | |
| Bronchiolitis obliterans | |