[1. Eriksson T, Bjorkman S, Hoglund P. Clinical pharmacology of thalidomide. Eur J Clin Pharmacol. 2001; 57(5):365-376.10.1007/s002280100320]Search in Google Scholar
[2. Melchert M, List A. The thalidomide saga. Int J Biochem Cell Biol. 2007; 39(7-8):1489-1499.1736907610.1016/j.biocel.2007.01.022]Search in Google Scholar
[3. Ridings JE. The thalidomide disaster, lessons from the past. Methods Mol Biol. 2013; 947:575-586.10.1007/978-1-62703-131-8_36]Search in Google Scholar
[4. Eriksson T, Bjorkman S, Roth B, Hoglund P. Intravenous formulations of the enantiomers of thalidomide: pharmacokinetic and initial pharmacodynamic characterization in man. J Pharm Pharmacol. 2000; 52(7):807-817.10.1211/002235700177466010933131]Open DOISearch in Google Scholar
[5. Höglund P, Eriksson T, Björkman S. A double-blind study of the sedative effects of the thalidomide enantiomers in humans. J Pharmacokinet and Biopharm. 1998; 26(4):363-383.1021455810.1023/A:1021008016719]Search in Google Scholar
[6. Nishimura K, Hashimoto Y, Iwasaki S. (S)-form of alpha-methyl-N(α)-phthalimidoglutarimide, but not its (R)-form, enhanced phorbol ester-induced tumor necrosis factor-alpha production by human leukemia cell HL-60: implication of optical resolution of thalidomidal effects. Chem Pharm Bull. 1994; 42(5):1157-1159.10.1248/cpb.42.11578069968]Open DOISearch in Google Scholar
[7. Wnendt S, Finkam M, Winter W, Ossig J, Raabe G, Zwingenberger K. Enantioselective inhibition of TNF-α release by thalidomide and thalidomide-analogues. Chirality. 1996; 8(5):390-396.10.1002/(SICI)1520-636X(1996)8:5<390::AID-CHIR6>3.0.CO;2-I]Open DOISearch in Google Scholar
[8. Tian C, Xiu P, Meng Y, Zhao W, Wang Z, Zhou R. Enantiomerization mechanism of thalidomide and the role of water and hydroxide ions. Chemistry. 2012 5; 18(45):14305-14313.10.1002/chem.201202651]Search in Google Scholar
[9. Wolf C. Dynamic stereochemistry of chiral compounds: principles and applications: RSC Publishing; 2008. p. 29-135.]Search in Google Scholar
[10. Sheskin J. Thalidomide in the Treatment of Lepra Reactions. Clin Pharmacol Ther. 1965; 6:303-306.1429602710.1002/cpt196563303]Search in Google Scholar
[11. Licht JD, Shortt J, Johnstone R. From anecdote to targeted therapy: the curious case of thalidomide in multiple myeloma. Cancer Cell. 2014; 25(1):9-11.10.1016/j.ccr.2013.12.019]Open DOISearch in Google Scholar
[12. Knight R. IMiDs: a novel class of immunomodulators. Semin Oncol. 2005; 32(4 Suppl 5): S24-30.10.1053/j.seminoncol.2005.06.01816085014]Open DOISearch in Google Scholar
[13. Łączkowski KZ, Baranowska-Łączkowska A. Recent studies on the thalidomide and its derivatives. Future Med Chem. 2018; 10(18) 2133-2136.10.4155/fmc-2018-021730088422]Search in Google Scholar
[14. Jacques V, Czarnik AW, Judge TM, Van der Ploeg LH, DeWitt SH. Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs. Proc Natl Acad Sci USA. 2015; 112(12):E1471-1479.10.1073/pnas.1417832112437838825775521]Search in Google Scholar
[15. Uttamsingh V, Gallegos R, Cheng C, Aslanian A, Liu JF, Tung R, Wu L. CTP-221, a deuterated S-enantiomer of lenalidomide, is greatly stabilized to epimerization and results in a more desirable pharmacokinetic profile than racemic lenalidomide. In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 3357. doi:10.1158/1538-7445.AM2013-3357 AACR; 2013.10.1158/1538-7445.AM2013-3357]Search in Google Scholar
[16. Wu L, Aslanian AM, Liu JF, Hogan K, Tung R. CTP-221, a Deuterated S-Enantiomer of Lenalidomide, Possesses Significantly Enhanced Immunomodulatory and Anti-Proliferative Properties Relative to the R-Enantiomer and to Racemic Lenalidomide. Blood 2012, 120:2463.10.1182/blood.V120.21.2463.2463]Search in Google Scholar
[17. Chung F, Palmer BD, Muller GW, Man HW, Kestell P, Baguley BC, et al. Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Oncol Res. 2003; 14(2):75-82.10.3727/00000000310874862114649541]Open DOISearch in Google Scholar
[18. Knabe J, Omlor G. [Synthesis of racemates and enantiomers of 3-alkylthalidomide analogs and determination of their absolute configuration]. Arch Pharm (Weinheim). 1989; 322(8):499-505.10.1002/ardp.198932208092604538]Search in Google Scholar
[19. Szabo ZI, Foroughbakhshfasaei M, Gal R, Horvath P, Komjati B, Noszal B, Tóth G. Chiral separation of lenalidomide by liquid chromatography on polysaccharide-type stationary phases and by capillary electrophoresis using cyclodextrin selectors. J Sep Sci. 2018; 41(6):1414-1423.10.1002/jssc.20170121129211341]Open DOISearch in Google Scholar
[20. Szabo ZI, Szocs L, Horvath P, Komjati B, Nagy J, Janoska A, Noszal B., Toth G. Liquid chromatography with mass spectrometry enantioseparation of pomalidomide on cyclodextrin-bonded chiral stationary phases and the elucidation of the chiral recognition mechanisms by NMR spectroscopy and molecular modeling. J Sep Sci. 2016; 39(15):2941-2949.10.1002/jssc.20160035427279456]Search in Google Scholar
[21. Szabó ZI, Mohammadhassan F, Szőcs L, Nagy J, Komjáti B, Noszál B, Toth G. Stereoselective interactions and liquid chromatographic enantioseparation of thalidomide on cyclodextrin-bonded stationary phases. J Incl Phenom Macrocycl Chem. 2016; 85(3-4):227-236.10.1007/s10847-016-0622-3]Search in Google Scholar
[22. Del Valle EM. Cyclodextrins and their uses: a review. Process Biochem. 2004; 39(9):1033-1046.10.1016/S0032-9592(03)00258-9]Open DOISearch in Google Scholar
[23. Szabo ZI, Toth G, Volgyi G, Komjati B, Hancu G, Szente L, Beni S, Muntean DL, Noszal B. Chiral separation of asenapine enantiomers by capillary electrophoresis and characterization of cyclodextrin complexes by NMR spectroscopy, mass spectrometry and molecular modeling. J Pharm Biomed Anal. 2016; 5(117):398-404.10.1016/j.jpba.2015.09.022]Search in Google Scholar
[24. Szejtli J. Cyclodextrin inclusion complexes. Cyclodextrin technology: Springer; 1988. p. 79-185.10.1007/978-94-015-7797-7_2]Search in Google Scholar
[25. Tóth G, Mohácsi R, Rácz Á, Rusu A, Horváth P, Szente L, Béni Sz, Noszál B. Equilibrium and structural characterization of ofloxacin–cyclodextrin complexation. J Incl Phenom Macrocycl Chem. 2013; 77(1-4):291-300.10.1007/s10847-012-0245-2]Search in Google Scholar
[26. Armstrong DW, DeMond W. Cyclodextrin bonded phases for the liquid chromatographic separation of optical, geometrical, and structural isomers. J Chrom Sci. 1984; 22(9):411-415.10.1093/chromsci/22.9.411]Search in Google Scholar
[27. Kawaguchi Y, Tanaka M, Nakae M, Funazo K, Shono T. Chemically bonded cyclodextrin stationary phases for liquid chromatographic separation of aromatic compounds. Anal Chem. 1983; 55(12):1852-1857.10.1021/ac00262a005]Search in Google Scholar
[28. Hinze WL, Riehl TE, Armstrong DW, DeMond W, Alak A, Ward T. Liquid chromatographic separation of enantiomers using a chiral β-cyclodextrin-bonded stationary phase and conventional aqueous-organic mobile phases. Anal Chem. 1985;57(1):237-242.10.1021/ac00279a055]Search in Google Scholar
[29. GuangáLan W, KayáChee K, KeongáWong M, KeeáLee H, MináSin Y. Orthogonal array design as a chemometric method for the optimization of analytical procedures. Part 4. Mixed-level design and its application to the high-performance liquid chromatographic determination of polycyclic aromatic hydrocarbons. Analyst. 1995; 120(2):281-287.10.1039/an9952000281]Search in Google Scholar
[30. Neumajer G, Sohajda T, Darcsi A, Toth G, Szente L, Noszal B, Béni Sz Chiral recognition of dapoxetine enantiomers with methylated-gamma-cyclodextrin: a validated capillary electrophoresis method. J Pharm Biomed Anal.. 2012; 62:42-47.]Search in Google Scholar
[31. Wan HB, Lan WG, Wong MK, Mok CY. Orthogonal array designs for the optimization of liquid chromatographic analysis of pesticides. Anal Chim Acta. 1994; 289(3):371-380.10.1016/0003-2670(94)90014-2]Search in Google Scholar