Acute and sub-chronic toxicity study of recombinant bovine interferon alpha in rodents

1Ameni A.Z., Latorre O.A., Torres L.M., Górniak S.L.: Toxicity study about a medicinal plant Casearia sylvestris: A contribution to the Brazilian Unified Health System (SUS). J Ethnopharmacol 2015, 175, 9–13, doi: 10.1016/j.jep.2015.08.027. Ameni A.Z. Latorre O.A. Torres L.M. Górniak S.L. Toxicity study about a medicinal plant Casearia sylvestris: A contribution to the Brazilian Unified Health System (SUS) J Ethnopharmacol 2015 175 9 13 doi 10.1016/j.jep.2015.08.027Open DOISearch in Google Scholar

2Chinsangaram J., Piccone M.E., Grubman M.J.: Ability of foot-and-mouth disease virus to form plaques in cell culture is associated with suppression of alpha/beta interferon. J Virol 1999, 73, 9891–9898, doi: 10.1128/JVI.73.12.9891-9898.1999. Chinsangaram J. Piccone M.E. Grubman M.J. Ability of foot-and-mouth disease virus to form plaques in cell culture is associated with suppression of alpha/beta interferon J Virol 1999 73 9891 9898 doi 10.1128/JVI.73.12.9891-9898.1999Open DOISearch in Google Scholar

3Dunn G.P., Koebel C.M., Schreiber R.D.: Interferons, immunity and cancer immunoediting. Nat Rev Immunol 2006, 6, 836–848, doi:10.1038/nri1961. Dunn G.P. Koebel C.M. Schreiber R.D. Interferons, immunity and cancer immunoediting Nat Rev Immunol 2006 6 836 848 doi10.1038/nri1961Open DOISearch in Google Scholar

4Edmonson J.H., Kovach J.S., Buckner J.C., Kvols L.K., Hahn R.G.: Phase I study of difluoromethylornithine in combination with recombinant alpha 2a-interferon. Cancer Res 1988, 48, 6584–6586. Edmonson J.H. Kovach J.S. Buckner J.C. Kvols L.K. Hahn R.G. Phase I study of difluoromethylornithine in combination with recombinant alpha 2a-interferon Cancer Res 1988 48 6584 6586Search in Google Scholar

5Einhorn S., Strander H.: Is interferon tissue specific? Effect of human leukocyte and fibroblast interferons on the growth of lymphoblastoid and osteosarcoma cell lines. J Gen Virol 1977, 35, 573–577, doi: 10.1099/0022-1317-35-3-573. Einhorn S. Strander H. Is interferon tissue specific? Effect of human leukocyte and fibroblast interferons on the growth of lymphoblastoid and osteosarcoma cell lines J Gen Virol 1977 35 573 577 doi 10.1099/0022-1317-35-3-573Open DOISearch in Google Scholar

6Goodkin D.E.: Interferon beta therapy for multiple sclerosis. Lancet 1998, 352, 1486–1487, doi: 10.1016/S0140-6736(98)00057-9. Goodkin D.E. Interferon beta therapy for multiple sclerosis Lancet 1998 352 1486 1487 doi 10.1016/S0140-6736(98)00057-9Open DOISearch in Google Scholar

7Isaacs A., Lindenmann J.: Virus interference. I. The interferon. Proc R Soc Lond B Biol Sci 1957, 147, 258–267, doi: 10.1098/rspb.1957.0048. Isaacs A. Lindenmann J. Virus interference. I. The interferon Proc R Soc Lond B Biol Sci 1957 147 258 267 doi 10.1098/rspb.1957.004813465720Open DOISearch in Google Scholar

8Kim H.-C., Kang B.-H., Ha C.-S., Han S.-S., Roh J.-K.: An acute toxicity study of recombinant human interferon alpha A (LBD-007) in Sprague-Dawley rats. J Toxicol Sci 1993, 18 Suppl 2, 37–42, doi: 10.2131/jts.18.supplementii_37. Kim H.-C. Kang B.-H. Ha C.-S. Han S.-S. Roh J.-K. An acute toxicity study of recombinant human interferon alpha A (LBD-007) in Sprague-Dawley rats J Toxicol Sci 1993 18 Suppl 2 37 42 doi 10.2131/jts.18.supplementii_378355289Open DOISearch in Google Scholar

9Koyama R., Arase Y., Ikeda K., Suzuki F., Suzuki Y., Saitoh S., Kobayashi M., Akuta N., Someya T., Hosaka T., Sezaki H., Kobayashi M., Kumada H.: Efficacy of interferon therapy in elderly patients with chronic hepatitis C. Intervirology 2006, 49, 121–126, doi: 10.1159/000089372. Koyama R. Arase Y. Ikeda K. Suzuki F. Suzuki Y. Saitoh S. Kobayashi M. Akuta N. Someya T. Hosaka T. Sezaki H. Kobayashi M. Kumada H. Efficacy of interferon therapy in elderly patients with chronic hepatitis C Intervirology 2006 49 121 126 doi 10.1159/00008937216428887Open DOISearch in Google Scholar

10Li Y., Zhang X., Liang C., Hu J., Yu Z.: Safety evaluation of mulberry leaf extract: Acute, subacute toxicity and genotoxicity studies. Regul Toxicol Pharmacol 2018, 95, 220–226, doi: 10.1016/j.yrtph.2018.03.007. Li Y. Zhang X. Liang C. Hu J. Yu Z. Safety evaluation of mulberry leaf extract: Acute, subacute toxicity and genotoxicity studies Regul Toxicol Pharmacol 2018 95 220 226 doi 10.1016/j.yrtph.2018.03.00729530616Open DOISearch in Google Scholar

11Marcus P.I., van der Heide L., Sekellick M.J.: Interferon action on avian viruses. I. Oral administration of chicken interferon-alpha ameliorates Newcastle disease. J Interferon Cytokine Res 1999, 19, 881–885, doi: 10.1089/107999099313406. Marcus P.I. van der Heide L. Sekellick M.J. Interferon action on avian viruses. I. Oral administration of chicken interferon-alpha ameliorates Newcastle disease J Interferon Cytokine Res 1999 19 881 885 doi 10.1089/10799909931340610476933Open DOISearch in Google Scholar

12Ohmann H.B., Gilchrist J.E., Babiuk L.A.: Effect of recombinant DNA-produced bovine interferon alpha (BoIFN-alpha 1) on the interaction between bovine alveolar macrophages and bovine herpesvirus type 1. J Gen Virol 1984, 65, 1487–1495, doi: 10.1099/0022-1317-65-9-1487. Ohmann H.B. Gilchrist J.E. Babiuk L.A. Effect of recombinant DNA-produced bovine interferon alpha (BoIFN-alpha 1) on the interaction between bovine alveolar macrophages and bovine herpesvirus type 1 J Gen Virol 1984 65 1487 1495 doi 10.1099/0022-1317-65-9-14876470681Open DOISearch in Google Scholar

13Organisation for Economic Co-operation and Development: Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents, OECD Guidelines for the Testing of Chemicals, Section 4. OECD Publishing, Paris, 2008, doi: 10.1787/9789264070684-en. Organisation for Economic Co-operation and Development: Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents, OECD Guidelines for the Testing of Chemicals, Section 4 OECD Publishing Paris 2008 doi 10.1787/9789264070684-enOpen DOISearch in Google Scholar

14Shin J.-H., Moon H.-J., Kim T.-S., Kang I.H., Ki H.Y., Choi K.-S., Han S.-Y.: Repeated 28-day oral toxicity study of vinclozolin in rats based on the draft protocol for the “Enhanced OECD Test Guideline No. 407” to detect endocrine effects. Arch Toxicol 2006, 80, 547–554, doi: 10.1007/s00204-006-0080-6. Shin J.-H. Moon H.-J. Kim T.-S. Kang I.H. Ki H.Y. Choi K.-S. Han S.-Y. Repeated 28-day oral toxicity study of vinclozolin in rats based on the draft protocol for the “Enhanced OECD Test Guideline No. 407” to detect endocrine effects Arch Toxicol 2006 80 547 554 doi 10.1007/s00204-006-0080-616489464Open DOISearch in Google Scholar

15Tabarraei H., Hassan J., Parvizi M.R., Golshahi H., Keshavarz-Tarikhi H.: Evaluation of the acute and sub-acute toxicity of the black caraway seed essential oil in Wistar rats. Toxicol Rep 2019, 6, 869–874, doi: 10.1016/j.toxrep.2019.08.010. Tabarraei H. Hassan J. Parvizi M.R. Golshahi H. Keshavarz-Tarikhi H. Evaluation of the acute and sub-acute toxicity of the black caraway seed essential oil in Wistar rats Toxicol Rep 2019 6 869 874 doi 10.1016/j.toxrep.2019.08.010671928431497509Open DOISearch in Google Scholar

16Thivolet J., Nicolas J.F., Kanitakis J., Lyonnet S., Chouvet B.: Recombinant interferon alpha 2a is effective in the treatment of discoid and subacute cutaneous lupus erythematosus. Br J Dermatol 1990, 122, 405–409, doi: 10.1111/j.1365-2133.1990.tb08290.x. Thivolet J. Nicolas J.F. Kanitakis J. Lyonnet S. Chouvet B. Recombinant interferon alpha 2a is effective in the treatment of discoid and subacute cutaneous lupus erythematosus Br J Dermatol 1990 122 405 409 doi 10.1111/j.1365-2133.1990.tb08290.x2182099Open DOISearch in Google Scholar

17Tu Y.B., Wang G., Wang Y.-Q., Chen W.-Y., Zhang L., Liu Y.-G., Jiang C.-G., Wang S.-J., Bu Z.-G., Cai X.-H.: Extracellular expression and antiviral activity of a bovine interferon-alpha through codon optimization in Pichia pastoris. Microbiol Res 2016, 191, 12–18, doi: 10.1016/j.micres.2016.05.009. Tu Y.B. Wang G. Wang Y.-Q. Chen W.-Y. Zhang L. Liu Y.-G. Jiang C.-G. Wang S.-J. Bu Z.-G. Cai X.-H. Extracellular expression and antiviral activity of a bovine interferon-alpha through codon optimization in Pichia pastoris Microbiol Res 2016 191 12 18 doi 10.1016/j.micres.2016.05.00927524649Open DOISearch in Google Scholar

18Van Wyk B., Snider M., Scruten E., Littel-van den Hurk S.V., Napper S.: Induction of functional interferon alpha and gamma responses during acute infection of cattle with non-cytopathic bovine viral diarrhea virus. Vet Microbiol 2016, 195, 104–114, doi: 10.1016/j.vetmic.2016.09.015. Van Wyk B. Snider M. Scruten E. Littel-van den Hurk S.V. Napper S. Induction of functional interferon alpha and gamma responses during acute infection of cattle with non-cytopathic bovine viral diarrhea virus Vet Microbiol 2016 195 104 114 doi 10.1016/j.vetmic.2016.09.01527771055Open DOISearch in Google Scholar

19Vilar Gomez E., Grá Oramas B., Arús Soler E., Ruenes Domech C., Davila Gonzalez Y.: Sequential combination therapy with prednisone, lamivudine and interferon alfa-2b for HBeAg-positive chronic hepatitis B. Gastroenterol Hepatol 2006, 29, 534–541. Vilar Gomez E. Grá Oramas B. Arús Soler E. Ruenes Domech C. Davila Gonzalez Y. Sequential combination therapy with prednisone, lamivudine and interferon alfa-2b for HBeAg-positive chronic hepatitis B Gastroenterol Hepatol 2006 29 534 54110.1157/1309434817129547Search in Google Scholar

20Wahid B., Shami K., Joiya S.A., Ozuyar S.E.G., Idrees M.: Comparing the risk of hypothyroidism in HCV patients treated with different DAA drugs combinations (sofosbuvir + interferon + ribavirin and sofosbuvir + daclatasvir + ribavirin). J Med Virol 2020, 92, 3868–3870, doi: 10.1002/jmv.25931. Wahid B. Shami K. Joiya S.A. Ozuyar S.E.G. Idrees M. Comparing the risk of hypothyroidism in HCV patients treated with different DAA drugs combinations (sofosbuvir + interferon + ribavirin and sofosbuvir + daclatasvir + ribavirin) J Med Virol 2020 92 3868 3870 doi 10.1002/jmv.2593132419178Open DOISearch in Google Scholar

21Walder C.E., Thiemermann C., Vane J.R.: Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa. Proc Biol Sci 1990, 241, 195–200, doi: 10.1098/rspb.1990.0085. Walder C.E. Thiemermann C. Vane J.R. Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa Proc Biol Sci 1990 241 195 200 doi 10.1098/rspb.1990.00851979444Open DOISearch in Google Scholar

22Yu H.-Y., Liu J., He Z.-Y., Zhou W., Xia B.-B., Wang M., Chen J., Wang M.-L., Jiang G.-T., Zhao J.: Soluble Expression, Rapid Purification and Antiviral Activity of Recimbinant Bovine Interferon-α in Escherichia coli. Appl Biochem Microbiol 2020, 56, 154–163, doi: 10.1134/S0003683820020143. Yu H.-Y. Liu J. He Z.-Y. Zhou W. Xia B.-B. Wang M. Chen J. Wang M.-L. Jiang G.-T. Zhao J. Soluble Expression, Rapid Purification and Antiviral Activity of Recimbinant Bovine Interferon-α in Escherichia coli Appl Biochem Microbiol 2020 56 154 163 doi 10.1134/S0003683820020143Open DOISearch in Google Scholar

23Zhao J., Yu H.Y., Zhang J.L., Wang X.M., Li J.P., Hu T., Hu Y., Wang M.L., Shen Y.Z., Xu J.D., Han G.X., Chen J.: Pharmacokinetic studies of the recombinant chicken interferon-alpha in broiler chickens. J Vet Med Sci 2017, 79, 314–319, doi: 10.1292/jvms.15-0681. Zhao J. Yu H.Y. Zhang J.L. Wang X.M. Li J.P. Hu T. Hu Y. Wang M.L. Shen Y.Z. Xu J.D. Han G.X. Chen J. Pharmacokinetic studies of the recombinant chicken interferon-alpha in broiler chickens J Vet Med Sci 2017 79 314 319 doi 10.1292/jvms.15-0681532693627890904Open DOISearch in Google Scholar