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Effects of vitamin C supplementation on the blood oxidative stress and antibody titre against Histophilus somni vaccination in calves

Konosuke Otomaru
Konosuke Otomaru
, 
Shoko Oishi
Shoko Oishi
, 
Yu Fujimura
Yu Fujimura
, 
Yuki Iwamoto
Yuki Iwamoto
, 
Katsuhisa Nagai
Katsuhisa Nagai
 and 
Moe Ijiri
Moe Ijiri
   | Dec 29, 2020
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Published Online: Dec 29, 2020
Page range: 73 - 78
Received: Jul 06, 2020
Accepted: Dec 07, 2020
DOI: https://doi.org/10.2478/jvetres-2021-0002
Keywords
© 2021 K. Otomaru et al. published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1

Changes in serum derivatives of reactive oxygen metabolites (d-ROMs) in the VC group (solid squares) and the control group (hollow squares) The amount of d-ROMs corresponds to the amount of hydrogen peroxide The asterisk indicates a significant difference between groups at the same age (P < 0.05) Data are shown as mean ± SE
Changes in serum derivatives of reactive oxygen metabolites (d-ROMs) in the VC group (solid squares) and the control group (hollow squares) The amount of d-ROMs corresponds to the amount of hydrogen peroxide The asterisk indicates a significant difference between groups at the same age (P < 0.05) Data are shown as mean ± SE

Fig. 2

Changes in serum biological antioxidant potential (BAP) in the VC group (solid squares) and the control group (hollow squares) Data are shown as mean ± SE
Changes in serum biological antioxidant potential (BAP) in the VC group (solid squares) and the control group (hollow squares) Data are shown as mean ± SE

Fig. 3

Changes in oxidative stress index (OSI) in the VC group (solid squares) and the control group (hollow squares) The asterisk indicates a significant difference between groups at the same age (P < 0.05) Data are shown as mean ± SE
Changes in oxidative stress index (OSI) in the VC group (solid squares) and the control group (hollow squares) The asterisk indicates a significant difference between groups at the same age (P < 0.05) Data are shown as mean ± SE

Fig. 4

Changes in antibody titres against Histophilus somni in the VC group (solid squares) and the control group (hollow squares) The asterisk indicates a significant difference between groups at the same age (P < 0.05) Data are shown as mean ± SE
Changes in antibody titres against Histophilus somni in the VC group (solid squares) and the control group (hollow squares) The asterisk indicates a significant difference between groups at the same age (P < 0.05) Data are shown as mean ± SE

Amount and nutrient composition of feed without supplement (per head per day)

Weeks of age
2 4 8 12
Amount (dry matter; kg)
Milk replacer 0.90 1.08 1.08 0.00
Concentrate 0.04 0.09 0.45 1.08
Oats 0.01 0.01 0.08 0.16
Composition (dry basis; %)
Total digestible nutrients 103.4 102.4 95.8 77.5
Crude protein 27.4 27.1 24.9 18.8
Crude fat 15.5 15.1 11.8 2.2
Calcium 1.34 1.31 1.13 0.61
Phosphorous 0.72 0.71 0.66 0.52
Magnesium 0.11 0.11 0.14 0.21

Haematological parameters

Parameter Weeks of age
2 4 8 12
White blood cells (102 cell/μL) VC group Control group 86.0 ± 5.4 79.6 ± 5.3 80.4 ± 3.6 88.4 ± 4.1 81.6 ± 5.4 88.2 ± 5.5 82.4 ± 5.9 83.8 ± 3.2
Red blood cells (104 cell/μL) VC group Control group 846 ± 23 893 ± 29 948 ± 30 1007 ± 26 1022 ± 22 1102 ± 24 1057 ± 20 1099 ± 36
Haemoglobin (g/dL) VC group Control group 9.8 ± 0.2 9.9 ± 0.3 10.5 ± 0.4 10.6 ± 0.3 10.9 ± 0.2 11.4 ± 0.2 11.2 ± 0.2 11.7 ± 0.2
Haematocrit (%) VC group Control group 31.9 ± 0.8 32.1 ± 1.0 33.6 ± 1.1 33.6 ± 0.9 34.4 ± 0.7 35.6 ± 0.7 35.3 ± 0.7 35.3 ± 0.8
eISSN:
2450-8608
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Life Sciences, Molecular Biology, Microbiology and Virology, other, Medicine, Veterinary Medicine
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