Occult hepatitis B virus infection in people with haemophilia in South Africa
O Kgotleng
Department of Haematology, National Health Laboratory Service, University of PretoriaSouth Africa
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, N Msomi
Discipline of Virology, National Health Laboratory Service, University of KwaZulu NatalSouth Africa
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, LD Mthethwa
Discipline of Virology, National Health Laboratory Service, University of KwaZulu NatalSouth Africa
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, J Potgieter
Department of Haematology, National Health Laboratory Service, University of PretoriaSouth Africa
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, JN Mahlangu
Department of Molecular Medicine and Haematology, Faculty of Health Science, National Health Laboratory, University of WitwatersrandSouth Africa
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, M Karodia
Division of Clinical Haematology, Gauteng Department of Health, University of Sefako MakgathoSouth Africa
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and NL Ntabeni
Department of Haematology, National Health Laboratory Service, University of PretoriaSouth Africa
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Jun 10, 2025
About this article
Article Category: Clinical Research
Published Online: Jun 10, 2025
Page range: 65 - 70
DOI: https://doi.org/10.2478/jhp-2025-0009
Keywords
© 2025 O Kgotleng et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Figure 1.
Demographic and clinical characteristics of study participants
| Median age (years) | 29 |
| Born before 1991 (N) | 18 |
| Haemophilia A | 59 (89.4%) |
| Haemophilia B | 7 (10.6%) |
| Mild | 2 (3.03%) |
| Severe | 64 (96.9%) |
| Positive | 10 (15.1%) |
| Negative | 56 (84.8%) |
| SBAH | 23 (34.9%) |
| DGMAH | 7 (10.6%) |
| 36 (54.6%) | |
Serology results of study participants
| HIV | Positive | 5 (7.6%) |
| Negative | 61 (95.3%) | |
| Anti-HCV IgG | Positive | 0 |
| Negative | 66 (100%) | |
| Anti-HBc total | Positive | 5 (7.6%) |
| Negative | 61 (95.3%) | |
| Anti-HBs | Positive | 56 (84.8%) |
| Negative | 10 (15.1%) | |