<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Sheehan’s syndrome is a life-threatening endocrine emergency seen in postpartum females secondary to ischemic pituitary necrosis. It is a frequent cause of hypopituitarism in developing countries that occurs secondary to postpartum haemorrhage (PPH). Patients with Sheehan’s syndrome often present with organ dysfunctions in critical care settings, secondary to stressors precipitating the underlying hormonal deficiencies. The initial clinical picture of Sheehan’s syndrome may mimic some other disease, leading to misdiagnosis and diagnostic delay. Strict vigilance, timely diagnosis, and appropriate management are essential to avoid diagnostic delay and to improve the patient outcome. In this case series, we describe 5 cases of previously undiagnosed Sheehan’s syndrome (including young, middle aged and postmenopausal females) that presented to critical care and emergency settings with organ failures.</p></abstract>

Sheehan’s syndrome is a life-threatening endocrine emergency seen in postpartum females secondary to ischemic pituitary necrosis. It is a frequent cause of hypopituitarism in developing countries that occurs secondary to postpartum haemorrhage (PPH). Patients with Sheehan’s syndrome often present with organ dysfunctions in critical care settings, secondary to stressors precipitating the underlying hormonal deficiencies. The initial clinical picture of Sheehan’s syndrome may mimic some other disease, leading to misdiagnosis and diagnostic delay. Strict vigilance, timely diagnosis, and appropriate management are essential to avoid diagnostic delay and to improve the patient outcome. In this case series, we describe 5 cases of previously undiagnosed Sheehan’s syndrome (including young, middle aged and postmenopausal females) that presented to critical care and emergency settings with organ failures.

A Challenging Diagnosis of Sheehan’s Syndrome in Non-obstetric Critical Care and Emergency Settings: A Case Series of Five Patients with Varied Presentations

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

Sheehan’s syndrome is a life-threatening endocrine emergency seen in postpartum females secondary to ischemic pituitary necrosis. It is a frequent cause of...

A Challenging Diagnosis of Sheehan’s Syndrome in Non-obstetric Critical Care and Emergency Settings: A Case Series of Five Patients with Varied Presentations

Article Category: Research Article

Published Online: Aug 12, 2022

Page range: 214 - 222

Received: Jan 21, 2022

Accepted: Jun 14, 2022

DOI: https://doi.org/10.2478/jccm-2022-0018

Keywords
Sheehan’s syndrome, hypopituitarism, pituitary necrosis, postpartum haemorrhage

© 2022 Suhail Sarwar Siddiqui, Nibu Dominic, Sukriti Kumar, Kauser Usman, Sai Saran, Avinash Agrawal, Mohan Gurjar, Syed Nabeel Muzaffar, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

A Challenging Diagnosis of Sheehan’s Syndrome in Non-obstetric Critical Care and Emergency Settings: A Case Series of Five Patients with Varied Presentations

Article Category: Research Article

Published Online: Aug 12, 2022

Page range: 214 - 222

Received: Jan 21, 2022

Accepted: Jun 14, 2022

DOI: https://doi.org/10.2478/jccm-2022-0018

KeywordsSheehan’s syndrome, hypopituitarism, pituitary necrosis, postpartum haemorrhage

© 2022 Suhail Sarwar Siddiqui, Nibu Dominic, Sukriti Kumar, Kauser Usman, Sai Saran, Avinash Agrawal, Mohan Gurjar, Syed Nabeel Muzaffar, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
Sheehan’s syndrome, hypopituitarism, pituitary necrosis, postpartum haemorrhage