<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_jccm-2022-0008_s_006">
<h3>Introduction</h3>
<p>Hyperbaricoxygen therapy (HBOT) is breathing100% oxygen in pressurised chamber. This therapy ensures quick oxygen delivery to the bloodstream. In patients with severe COVID-19 pneumonia, progressive hypoxemia occurs. Oxygen therapy hasa significant role in its management.</p>
</sec>
<sec id="j_jccm-2022-0008_s_007">
<h3>Aim of the study</h3>
<p>The objective was to study the efficacy of hyperbaric oxygen therapy (HBOT) as adjuvant therapy for reducing the requirement of additional oxygen supplementationin patients with moderate to severe ARDS diagnosed with COVID-19.</p>
</sec>
<sec id="j_jccm-2022-0008_s_008">
<h3>Methods</h3>
<p>A single-centre prospective pilot cohort study was conducted ata tertiary care hospital from December 2020 to February 2021 over two months. Fifty patients with COVID-19 needingoxygen, satisfying the selection criteria, were included. Hyperbaricoxygen therapy wasgiven to all patients. The patient received30-45 minutes of hyperbaric oxygen with 15 minutes of pressurizing and depressurizing at 2.0 atmosphere absolute (ATA) with or without airbrakesas per the critical care team. Oxygen requirement, PaO2, andcondition at discharge were considered as primary outcome variables.</p>
</sec>
<sec id="j_jccm-2022-0008_s_009">
<h3>Results</h3>
<p>Among the 50 participants studied, the mean age was 53.64±13.26 years. Out of 50 participants, 49(98.00%) had PaO2≤80 mmHg, and one (2.00%) had >80 PaO2. All the participants 50(100%) had PaO2 as 90 mmHg after three sittings.</p>
</sec>
<sec id="j_jccm-2022-0008_s_010">
<h3>Conclusion</h3>
<p>This studyshows promising results in using HBOT to overcome respiratory failure in COVID-19. HBOT reduced the need for oxygen by improving the oxygen saturation levels.</p>
</sec>
</abstract>

Introduction
Hyperbaricoxygen therapy (HBOT) is breathing100% oxygen in pressurised chamber. This therapy ensures quick oxygen delivery to the bloodstream. In patients with severe COVID-19 pneumonia, progressive hypoxemia occurs. Oxygen therapy hasa significant role in its management.


Aim of the study
The objective was to study the efficacy of hyperbaric oxygen therapy (HBOT) as adjuvant therapy for reducing the requirement of additional oxygen supplementationin patients with moderate to severe ARDS diagnosed with COVID-19.


Methods
A single-centre prospective pilot cohort study was conducted ata tertiary care hospital from December 2020 to February 2021 over two months. Fifty patients with COVID-19 needingoxygen, satisfying the selection criteria, were included. Hyperbaricoxygen therapy wasgiven to all patients. The patient received30-45 minutes of hyperbaric oxygen with 15 minutes of pressurizing and depressurizing at 2.0 atmosphere absolute (ATA) with or without airbrakesas per the critical care team. Oxygen requirement, PaO2, andcondition at discharge were considered as primary outcome variables.


Results
Among the 50 participants studied, the mean age was 53.64±13.26 years. Out of 50 participants, 49(98.00%) had PaO2≤80 mmHg, and one (2.00%) had >80 PaO2. All the participants 50(100%) had PaO2 as 90 mmHg after three sittings.


Conclusion
This studyshows promising results in using HBOT to overcome respiratory failure in COVID-19. HBOT reduced the need for oxygen by improving the oxygen saturation levels.

Effective Outcome of HBOT as an Adjuvant Therapy in Patients Diagnosed with COVID-19 in a Tertiary Care Hospital – A Preliminary Study

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

Introduction
Hyperbaricoxygen therapy (HBOT) is breathing100% oxygen in pressurised chamber. This therapy ensures quick oxygen delivery to the bloodstream. In...

Effective Outcome of HBOT as an Adjuvant Therapy in Patients Diagnosed with COVID-19 in a Tertiary Care Hospital – A Preliminary Study

Article Category: Research Article

Published Online: Aug 12, 2022

Page range: 176 - 181

Received: Aug 23, 2021

Accepted: Apr 23, 2022

DOI: https://doi.org/10.2478/jccm-2022-0008

Keywords
COVID-19, hyperbaric oxygen therapy, infectious diseases, partial pressure, oxygen

© 2022 Thiruppathy Palaniappan, Asif Shaikh, Navamani Kirthika, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Effective Outcome of HBOT as an Adjuvant Therapy in Patients Diagnosed with COVID-19 in a Tertiary Care Hospital – A Preliminary Study

Article Category: Research Article

Published Online: Aug 12, 2022

Page range: 176 - 181

Received: Aug 23, 2021

Accepted: Apr 23, 2022

DOI: https://doi.org/10.2478/jccm-2022-0008

KeywordsCOVID-19, hyperbaric oxygen therapy, infectious diseases, partial pressure, oxygen

© 2022 Thiruppathy Palaniappan, Asif Shaikh, Navamani Kirthika, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
COVID-19, hyperbaric oxygen therapy, infectious diseases, partial pressure, oxygen